The balance between protective and pathogenic immune responses in the TB-infected lung (Q38293027)

1 September 2017

1 reference

title

The balance between protective and pathogenic immune responses in the TB-infected lung (English)

1 reference

1 September 2017

Richard T Robinson

2

0 references

Andrea M. Cooper

object named as

Andrea M Cooper

series ordinal

3

0 references

Ian Orme

series ordinal

1

object named as

Ian M Orme

1 reference

PubMed ID

25521685

1 September 2017

language of work or name

English

0 references

publication date

1 January 2015

1 reference

1 September 2017

1 reference

1 September 2017

16

1 reference

1 September 2017

57-63

1 reference

1 September 2017

1

1 reference

Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness

1 September 2017

1 reference

Cell-mediated immune responses in tuberculosis

21 January 2018

1 reference

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

21 January 2018

1 reference

Host-pathogen coevolution in human tuberculosis

21 January 2018

1 reference

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

21 January 2018

1 reference

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset

21 January 2018

1 reference

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

21 January 2018

1 reference

Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation

21 January 2018

1 reference

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

21 January 2018

1 reference

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation

21 January 2018

1 reference

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate

21 January 2018

1 reference

C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor

21 January 2018

1 reference

Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule

21 January 2018

1 reference

Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis -induced inflammation and virulence

21 January 2018

1 reference

Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production

21 January 2018

1 reference

Human mucosal associated invariant T cells detect bacterially infected cells

21 January 2018

1 reference

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.

21 January 2018

1 reference

Multifunctional immune responses of HMBPP-specific Vγ2Vδ2 T cells in M. tuberculosis and other infections

21 January 2018

1 reference

Innate immune gene polymorphisms in tuberculosis

21 January 2018

1 reference

Inborn errors of IL-12/23- and IFN-gamma-mediated immunity: molecular, cellular, and clinical features

21 January 2018

1 reference

X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production

21 January 2018

1 reference

Human lung hydrolases delineate Mycobacterium tuberculosis-macrophage interactions and the capacity to control infection

21 January 2018

1 reference

Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice

21 January 2018

1 reference

Macrophages play a dual role during pulmonary tuberculosis in mice

21 January 2018

1 reference

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

21 January 2018

1 reference

Neutrophil-mediated innate immune resistance to mycobacteria

21 January 2018

1 reference

The genetic theory of infectious diseases: a brief history and selected illustrations

21 January 2018

1 reference

Immune vulnerability of infants to tuberculosis

21 January 2018

1 reference

T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection

21 January 2018

1 reference

Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity.

21 January 2018

1 reference

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes

21 January 2018

1 reference

Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs

21 January 2018

1 reference

A new unifying theory of the pathogenesis of tuberculosis

21 January 2018

1 reference

Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice

21 January 2018

1 reference

The role of the granuloma in expansion and dissemination of early tuberculous infection

21 January 2018

1 reference

Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas

21 January 2018

1 reference

Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas.

21 January 2018

1 reference

Cutting edge: a new approach to modeling early lung immunity in murine tuberculosis.

21 January 2018

1 reference

Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection

21 January 2018

1 reference

Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration

21 January 2018

1 reference

Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis

21 January 2018

1 reference

Essential yet limited role for CCR2⁺ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming

21 January 2018

1 reference

Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M. tuberculosis infection

21 January 2018

1 reference

Characterization of murine lung dendritic cells infected with Mycobacterium tuberculosis

21 January 2018

1 reference

Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo.

21 January 2018

1 reference

Tuberculosis triggers a tissue-dependent program of differentiation and acquisition of effector functions by circulating monocytes.

21 January 2018

1 reference

Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

21 January 2018

1 reference

Interferon-gamma-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosis

21 January 2018

1 reference

Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

21 January 2018

1 reference

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

21 January 2018

1 reference

Cutting edge: Direct recognition of infected cells by CD4 T cells is required for control of intracellular Mycobacterium tuberculosis in vivo

21 January 2018

1 reference

In a murine tuberculosis model, the absence of homeostatic chemokines delays granuloma formation and protective immunity

21 January 2018

1 reference

Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host defence in the lung.

21 January 2018

1 reference

Mycobacterium tuberculosis triggers formation of lymphoid structure in murine lungs.

21 January 2018

1 reference

IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung

21 January 2018

1 reference

Cutting edge: control of Mycobacterium tuberculosis infection by a subset of lung parenchyma-homing CD4 T cells

21 January 2018

1 reference

Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features

21 January 2018

1 reference

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

21 January 2018

1 reference

Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis

21 January 2018

1 reference

Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis

21 January 2018

1 reference

Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12.

21 January 2018

1 reference

Mycobacterium bovis BCG-mediated protection against W-Beijing strains of Mycobacterium tuberculosis is diminished concomitant with the emergence of regulatory T cells

21 January 2018

1 reference

Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

21 January 2018

1 reference

Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection

21 January 2018

1 reference

Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages

21 January 2018

1 reference

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

21 January 2018

1 reference

Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death

21 January 2018

1 reference

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

21 January 2018

1 reference

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

21 January 2018

1 reference

The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans

21 January 2018

1 reference

Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections

21 January 2018

1 reference

Nitric oxide inhibits the accumulation of CD4+CD44hiTbet+CD69lo T cells in mycobacterial infection

21 January 2018

1 reference

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β.

21 January 2018

1 reference

Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature

21 January 2018

1 reference

IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

21 January 2018

1 reference

IFN-γ and NO in mycobacterial disease: new jobs for old hands

21 January 2018

1 reference

CXCR5⁺ T helper cells mediate protective immunity against tuberculosis

21 January 2018

1 reference

12 December 2020

Improved clearance of Mycobacterium avium upon disruption of the inducible nitric oxide synthase gene.

1 reference

12 December 2020

Tuberculosis in patients with human immunodeficiency virus infection

1 reference

12 December 2020

The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation

1 reference

12 December 2020

Revisiting the role of the granuloma in tuberculosis

1 reference

12 December 2020

Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.3048

1 reference

1 September 2017

1 reference

PubMed ID

25521685