Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor. (Q38294142)

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scientific article published on December 2001

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English	Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.	scientific article published on December 2001

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4 December 2019

Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor (English)

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4 December 2019

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Jean Marc Pascussi

1

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4 December 2019

Sabine Gerbal-Chaloin

3

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4 December 2019

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L Drocourt

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4 December 2019

J M Fabre

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4 December 2019

P Maurel

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4 December 2019

M J Vilarem

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4 December 2019

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1 December 2001

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4 December 2019

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4 December 2019

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4 December 2019

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4 December 2019

6346-6358

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4 December 2019

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

1 reference

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21 January 2018

P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

1 reference

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SXR, a novel steroid and xenobiotic-sensing nuclear receptor

1 reference

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

1 reference

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21 January 2018

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

1 reference

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21 January 2018

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

1 reference

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21 January 2018

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

1 reference

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21 January 2018

Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes

1 reference

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21 January 2018

A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids

1 reference

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21 January 2018

Sequence of the 5'-flanking region of CYP3A5: comparative analysis with CYP3A4 and CYP3A7

1 reference

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21 January 2018

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

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21 January 2018

Evidence for the presence of a functional pregnane X receptor response element in the CYP3A7 promoter gene

1 reference

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21 January 2018

Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes.

1 reference

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21 January 2018

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1 reference

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21 January 2018

Free cortisol in human plasma

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Abnormal EAAT2 splicing in amyotrophic lateral sclerosis

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21 January 2018

A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro

1 reference

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21 January 2018

Circadian variation of the urinary 6beta-hydroxycortisol to cortisol ratio that would reflect hepatic CYP3A activity

1 reference

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21 January 2018

Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.

1 reference

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21 January 2018

Identifiers

10.1046/J.0014-2956.2001.02540.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11737189%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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4 December 2019

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