Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation (Q38295214)

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scientific article published on 17 December 2007

Language	Label	Description	Also known as
English	Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation	scientific article published on 17 December 2007

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scholarly article

1 reference

Europe PubMed Central

1 September 2017

Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation (English)

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Europe PubMed Central

1 September 2017

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Bysani Chandrasekar

1

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Europe PubMed Central

1 September 2017

Devang N Patel

2

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Europe PubMed Central

1 September 2017

Srinivas Mummidi

3

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Europe PubMed Central

1 September 2017

Jae-woo Kim

4

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Europe PubMed Central

1 September 2017

Robert A Clark

5

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Europe PubMed Central

1 September 2017

Anthony J Valente

6

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Europe PubMed Central

1 September 2017

language of work or name

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publication date

17 December 2007

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Europe PubMed Central

1 September 2017

number of pages

10

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Journal of Biological Chemistry

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Europe PubMed Central

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283

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Europe PubMed Central

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4200-4209

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Europe PubMed Central

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7

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Europe PubMed Central

1 September 2017

cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1).

1 reference

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AdipoQ is a novel adipose-specific gene dysregulated in obesity

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Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

1 reference

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Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

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Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

1 reference

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Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin

1 reference

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Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages

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Effect of massive weight loss induced by bariatric surgery on serum levels of interleukin-18 and monocyte-chemoattractant-protein-1 in morbid obesity.

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Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans

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Elevated interleukin-18 levels are associated with the metabolic syndrome independent of obesity and insulin resistance.

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Associations of serum IL-18 levels with carotid intima-media thickness

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Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis

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A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways

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Recruitment of the extracellular signal-regulated kinase/ribosomal S6 kinase signaling pathway to the NFATc4 transcription activation complex

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Chemokine-cytokine cross-talk. The ELR+ CXC chemokine LIX (CXCL5) amplifies a proinflammatory cytokine response via a phosphatidylinositol 3-kinase-NF-kappa B pathway

1 reference

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CCAAT/enhancer binding protein and nuclear factor-Y regulate adiponectin gene expression in adipose tissue

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Interleukin-17 stimulates C-reactive protein expression in hepatocytes and smooth muscle cells via p38 MAPK and ERK1/2-dependent NF-kappaB and C/EBPbeta activation

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Activation of intrinsic and extrinsic proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death

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Esculetin induces apoptosis and inhibits adipogenesis in 3T3-L1 cells

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Adiponectin mediates the suppressive effect of rosiglitazone on plasminogen activator inhibitor-1 production

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Transcriptional regulation by calcium, calcineurin, and NFAT

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NFAT signaling and the invention of vertebrates

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Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth

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A novel serum protein similar to C1q, produced exclusively in adipocytes

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21 January 2018

Recent advances in the measurement of adiponectin isoform distribution

1 reference

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21 January 2018

Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: evidence for regulation of multimerization by alterations in posttranslational modifications.

1 reference

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Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

1 reference

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21 January 2018

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity

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21 January 2018

Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

1 reference

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Interleukin-18 enhances atherosclerosis in apolipoprotein E(-/-) mice through release of interferon-gamma

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Effect of weight loss induced by gastric bypass on proinflammatory interleukin-18, soluble tumour necrosis factor-alpha receptors, C-reactive protein and adiponectin in morbidly obese patients.

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Signal transduction pathways involved in rheumatoid arthritis synovial fibroblast interleukin-18-induced vascular cell adhesion molecule-1 expression

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The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Ak

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Identifiers

10.1074/JBC.M708142200

1 reference

Europe PubMed Central

1 September 2017

1 reference

Europe PubMed Central

1 September 2017

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