An extracellular domain of the beta subunit is essential for processing, transport and kinase activity of insulin receptor (Q38299770)

1 September 2017

An extracellular domain of the beta subunit is essential for processing, transport and kinase activity of insulin receptor (English)

1 reference

1 September 2017

Haruta T

1

1 reference

1 September 2017

Sawa T

2

1 reference

1 September 2017

Takata Y

3

1 reference

1 September 2017

Imamura T

4

1 reference

1 September 2017

Takada Y

5

1 reference

1 September 2017

Morioka H

6

1 reference

1 September 2017

Yang GH

7

1 reference

1 September 2017

Kobayashi M

8

1 reference

1 September 2017

language of work or name

English

0 references

publication date

1 January 1995

1 reference

1 September 2017

6

1 reference

inferred from page(s)

published in

Biochemical Journal

1 reference

1 September 2017

305 ( Pt 2)

1 reference

1 September 2017

599-604

1 reference

Specific glycosylation site mutations of the insulin receptor alpha subunit impair intracellular transport

1 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Mutational analysis of the NH2-terminal glycosylation sites of the insulin receptor alpha-subunit

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Post-translational acquisition of insulin binding activity by the insulin proreceptor. Correlation to recognition by autoimmune antibody

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Post-translational changes in tertiary and quaternary structure of the insulin proreceptor. Correlation with acquisition of function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Characterization of an insulin receptor mutant lacking the subunit processing site

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Substitution of lysine for asparagine at position 15 in the alpha-subunit of the human insulin receptor. A mutation that impairs transport of receptors to the cell surface and decreases the affinity of insulin binding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

The insulin receptor and the molecular mechanism of insulin action

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Immunoglobulin heavy chain-binding protein binds to misfolded mutant insulin receptors with mutations in the extracellular domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Kinetics of insulin receptor internalization and recycling in adipocytes. Shunting of receptors to a degradative pathway by inhibitors of recycling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Insulin resistance by unprocessed insulin proreceptors point mutation at the cleavage site.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Insulin-resistant diabetes due to a point mutation that prevents insulin proreceptor processing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

A primary defect in insulin receptor in a young male patient with insulin resistance

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Binding specificity and intramolecular signal transmission of uncleaved insulin proreceptor in transformed lymphocytes from a patient with extreme insulin resistance.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Transfection of cDNA with G----T point mutation at the cleavage site of insulin receptors to COS 7 cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

A leucine to proline mutation at position 233 in the insulin receptor inhibits cleavage of the proreceptor and transport to the cell surface

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

An Arg for Gly substitution at position 31 in the insulin receptor, linked to insulin resistance, inhibits receptor processing and transport

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Substitution of arginine for histidine at position 209 in the alpha-subunit of the human insulin receptor. A mutation that impairs receptor dimerization and transport of receptors to the cell surface

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

N-linked oligosaccharide chains of the insulin receptor beta subunit are essential for transmembrane signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Ala1048-->Asp mutation in the kinase domain of insulin receptor causes defective kinase activity and insulin resistance

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Insulin Resistance by Uncleaved Insulin Proreceptor: Emergence of Binding Site by Trypsin

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136404

Binding of insulin receptors to lectins: evidence for common carbohydrate determinants on several membrane receptors

31 August 2018

1 reference

12 December 2020

Effects of inhibitors of N-linked oligosaccharide processing on the biosynthesis and function of insulin and insulin-like growth factor-I receptors

1 reference

12 December 2020

Evidence for exogenous substrate phosphorylation and dimer formation by the activated 190 kDa insulin proreceptor in vitro

1 reference

12 December 2020

An extracellular domain of the insulin receptor beta-subunit with regulatory function on protein-tyrosine kinase

1 reference

12 December 2020

Unprocessed insulin proreceptor in cultured fibroblasts from a patient with extreme insulin resistance

1 reference

12 December 2020

Insulin-stimulated phosphorylation of the insulin receptor precursor

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ3050599

1 reference

release_e3zx3ebpzfaobislccnbbq2tde

1 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/e3zx3ebpzfaobislccnbbq2tde

24 November 2022

mapped directly with Wikidata item

1 reference

1 September 2017

1 reference