Phosphorothioate oligonucleotides block the VDAC channel (Q38302060)

1 September 2017

Phosphorothioate oligonucleotides block the VDAC channel (English)

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1 September 2017

Wenzhi Tan

1

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1 September 2017

Yue-Hin Loke

2

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1 September 2017

C A Stein

3

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1 September 2017

Paul Miller

4

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1 September 2017

Marco Colombini

5

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1 September 2017

language of work or name

English

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publication date

4 May 2007

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1 September 2017

8

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inferred from page(s)

published in

Biophysical Journal

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1 September 2017

93

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1 September 2017

4

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1 September 2017

1184-1191

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Phosphorothioate oligonucleotides reduce mitochondrial outer membrane permeability to ADP.

1 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

New insights into the mechanism of permeation through large channels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Dynamics of nucleotides in VDAC channels: structure-specific noise generation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Iontophoretic transport of oligonucleotides across human epidermal membrane: a study of the Nernst-Planck model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

The sensor regions of VDAC are translocated from within the membrane to the surface during the gating processes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Characterization of individual polynucleotide molecules using a membrane channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Formation of bimolecular membranes from lipid monolayers and a study of their electrical properties

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Structure of the mitochondrial outer membrane channel derived from electron microscopy of 2D crystals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Ultrasteep voltage dependence in a membrane channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Toward the molecular structure of the mitochondrial channel, VDAC

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Large scale rearrangement of protein domains is associated with voltage gating of the VDAC channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Regulation of the mitochondrial outer membrane channel, VDAC.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Phosphorothioate oligodeoxynucleotides and G3139 induce apoptosis in 518A2 melanoma cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Antisense RNA down-regulation of bcl-2 expression in DU145 prostate cancer cells does not diminish the cytostatic effects of G3139 (Oblimersen).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

The mitochondrial outer membrane channel, VDAC, is regulated by a synthetic polyanion.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Selectivity Changes in Site-Directed Mutants of the VDAC Ion Channel: Structural Implications

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

A candidate for the permeability pathway of the outer mitochondrial membrane

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

VDAC: the channel at the interface between mitochondria and the cytosol.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Actin modulates the gating of Neurospora crassa VDAC.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

Regulation of metabolite flux through voltage-gating of VDAC channels.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1929033

[27] Isolation and properties of the porin of the outer mitochondrial membrane from Neurospora crassa

31 August 2018

1 reference

12 December 2020

Characterization of channels isolated from plant mitochondria

1 reference

12 December 2020

Channel active mammalian porin, purified from crude membrane fractions of human B lymphocytes and bovine skeletal muscle, reversibly binds adenosine triphosphate (ATP)

1 reference

12 December 2020

Oriented channel insertion reveals the motion of a transmembrane beta strand during voltage gating of VDAC

1 reference

12 December 2020

The role of yeast VDAC genes on the permeability of the mitochondrial outer membrane

1 reference

12 December 2020

The topology of VDAC as probed by biotin modification

1 reference

12 December 2020

Mouse VDAC isoforms expressed in yeast: channel properties and their roles in mitochondrial outer membrane permeability

1 reference

12 December 2020

Driven DNA transport into an asymmetric nanometer-scale pore

1 reference

12 December 2020

Voltage gating of VDAC is regulated by nonlamellar lipids of mitochondrial membranes

1 reference

12 December 2020

Modification of lysine residues ofStaphylococcus aureus α-toxin: Effects on its channel-forming properties

1 reference

12 December 2020

Synergistic chemosensitization and inhibition of progression to androgen independence by antisense Bcl-2 oligodeoxynucleotide and paclitaxel in the LNCaP prostate tumor model

1 reference

12 December 2020

10.1529/BIOPHYSJ.107.105379

Identifiers

DOI

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1 September 2017

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1 September 2017

PubMed publication ID

17483171

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