Cytoskeleton and paclitaxel sensitivity in breast cancer: the role of beta-tubulins (Q38305006)

2 September 2017

Cytoskeleton and paclitaxel sensitivity in breast cancer: the role of beta-tubulins (English)

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2 September 2017

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Anita Mangia

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Maria Kavallaris

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Maria Kavallaris

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Rosanna Lacalamita

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Antonia Bellizzi

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Vita Fedele

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Annalisa Chiriatti

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Christopher Thomssen

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Nancy Kendzierski

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Agnese Latorre

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Vito Lorusso

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Francesco Schittulli

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Francesco Zito

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Angelo Paradiso

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language of work or name

English

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publication date

1 May 2007

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International Journal of Cancer

2 September 2017

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120

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10

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2 September 2017

2078-2085

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A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets

2 September 2017

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Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

21 January 2018

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Structure of the alpha beta tubulin dimer by electron crystallography

21 January 2018

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Microtubule alterations and mutations induced by desoxyepothilone B: implications for drug-target interactions

21 January 2018

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Altered beta-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells

21 January 2018

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Mutational analysis of the class I beta-tubulin gene in human breast cancer

21 January 2018

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Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer.

21 January 2018

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Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry.

21 January 2018

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Comparison of beta-tubulin mRNA and protein levels in 12 human cancer cell lines

21 January 2018

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Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression.

21 January 2018

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Differentiation of human colon cancer cells changes the expression of beta-tubulin isotypes and MAPs

21 January 2018

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Antisense oligonucleotides to class III beta-tubulin sensitize drug-resistant cells to Taxol

21 January 2018

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Biomarkers predictive for clinical efficacy of taxol-based chemotherapy in advanced breast cancer

21 January 2018

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Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells

21 January 2018

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Characterization of nuclear betaII-tubulin in tumor cells: a possible novel target for taxol

21 January 2018

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Mutations at leucine 215 of beta-tubulin affect paclitaxel sensitivity by two distinct mechanisms

21 January 2018

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Molecular and functional characteristics of erbB2 in normal and cancer breast cells

21 January 2018

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Mutational analysis of the beta-tubulin gene in lung cancer

21 January 2018

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Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics

21 January 2018

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Altered expression of M beta 2, the class II beta-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance

21 January 2018

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Microtubule-associated parameters as predictive markers of docetaxel activity in advanced breast cancer patients: results of a pilot study

21 January 2018

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Class III beta-tubulin overexpression is a marker of poor clinical outcome in advanced ovarian cancer patients.

21 January 2018

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Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer

21 January 2018

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A study of the value of p53, HER2, and Bcl-2 in the prediction of response to doxorubicin and paclitaxel as single agents in metastatic breast cancer: a companion study to EORTC 10923.

21 January 2018

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Assessment of molecular markers of clinical sensitivity to single-agent taxane therapy for metastatic breast cancer

21 January 2018

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p53-independent apoptosis induced by paclitaxel through an indirect mechanism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.22557

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2 September 2017

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