Src-mediated activation of alpha-diacylglycerol kinase is required for hepatocyte growth factor-induced cell motility. (Q38308665)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10970854%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Src-mediated activation of alpha-diacylglycerol kinase is required for hepatocyte growth factor-induced cell motility (English)

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9 November 2019

2

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9 November 2019

Enrico Giraudo

6

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9 November 2019

author name string

Cutrupi S

1

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9 November 2019

Gramaglia D

3

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9 November 2019

Maffè A

4

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9 November 2019

Schaap D

5

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9 November 2019

van Blitterswijk W

7

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9 November 2019

Bussolino F

8

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9 November 2019

Comoglio PM

9

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9 November 2019

Graziani A

10

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9 November 2019

language of work or name

English

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publication date

1 September 2000

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9 November 2019

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9 November 2019

volume

19

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9 November 2019

page(s)

4614-4622

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9 November 2019

issue

17

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Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation

9 November 2019

cites work

1 reference

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Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes

6 September 2017

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Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility

6 September 2017

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Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions

6 September 2017

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Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

6 September 2017

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The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

6 September 2017

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Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

6 September 2017

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Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta

6 September 2017

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Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

6 September 2017

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Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex

6 September 2017

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Src and Ras are involved in separate pathways in epithelial cell scattering

6 September 2017

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

6 September 2017

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The C-terminal part of diacylglycerol kinase alpha lacking zinc fingers serves as a catalytic domain

6 September 2017

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Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility

6 September 2017

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Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation

6 September 2017

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Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

6 September 2017

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Recognition and specificity in protein tyrosine kinase-mediated signalling

6 September 2017

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

6 September 2017

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Stimulation by phospholipids of a protein-tyrosine-phosphatase containing two src homology 2 domains

6 September 2017

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

6 September 2017

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Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol

6 September 2017

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Purification, cDNA-cloning and expression of human diacylglycerol kinase

6 September 2017

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The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase

6 September 2017

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The regulatory role of EF-hand motifs of pig 80K diacylglycerol kinase as assessed using truncation and deletion mutants.

6 September 2017

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Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

6 September 2017

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Phosphorylation and cytoskeletal anchoring of the acetylcholine receptor by Src class protein-tyrosine kinases. Activation by rapsyn

14 September 2017

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Diacylglycerol kinase inhibition prevents IL-2-induced G1 to S transition through a phosphatidylinositol-3 kinase-independent mechanism

27 September 2017

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c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells

27 September 2017

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Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

27 September 2017

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High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein

27 September 2017

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Increased concentrations of phosphatidate, diacylglycerol and ceramide in ras- and tyrosine kinase (fps)-transformed fibroblasts

27 September 2017

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Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product

27 September 2017

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Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET

27 September 2017

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HGF-mediated chemotaxis and tubulogenesis require activation of the phosphatidylinositol 3-kinase

27 September 2017

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Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

27 September 2017

1 reference

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Involvement of Ral GTPase in v-Src-induced phospholipase D activation

27 September 2017

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New developments in phospholipase D.

27 September 2017

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A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras.

23 June 2018

1 reference

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Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger.

23 June 2018

1 reference

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Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid.

23 June 2018

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Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

23 June 2018

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Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon

23 June 2018

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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

23 June 2018

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Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

23 June 2018

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Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

23 June 2018

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The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras.

23 June 2018

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Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.

31 August 2018

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Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability

31 August 2018

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Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. Phosphatidylinositol 3'-kinase is a critical mediator of tumor invasion.

31 August 2018

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Signal transduction. Phospholipids in action.

31 August 2018

1 reference

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Roles for the protein tyrosine phosphatase SHP-2 in cytoskeletal organization, cell adhesion and cell migration revealed by overexpression of a dominant negative mutant

31 August 2018

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12 December 2020

Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly

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12 December 2020

The regulation of phospholipase C-gamma 1 by phosphatidic acid. Assessment of kinetic parameters

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12 December 2020

Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics

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Phosphatidylinositol 3-kinase activity is required for hepatocyte growth factor-induced mitogenic signals in epithelial cells

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/19.17.4614

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10970854%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10970854%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference