Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase (Q38309170)

2 September 2017

title

Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase (English)

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2 September 2017

3

Eric T Kool

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2 September 2017

Lyudmila Yakovleva

1

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2 September 2017

Jacob Lai

series ordinal

2

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2 September 2017

Stewart Shuman

series ordinal

4

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2 September 2017

language of work or name

English

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publication date

27 September 2006

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

281

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2 September 2017

issue

47

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2 September 2017

page(s)

35914-35921

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Catalytic mechanism of DNA topoisomerase IB.

2 September 2017

cites work

1 reference

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Guarding the genome: electrostatic repulsion of water by DNA suppresses a potent nuclease activity of topoisomerase IB.

21 January 2018

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Mechanistic plasticity of DNA topoisomerase IB: phosphate electrostatics dictate the need for a catalytic arginine

21 January 2018

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Proteolytic footprinting of vaccinia topoisomerase bound to DNA.

21 January 2018

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Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases

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Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB.

21 January 2018

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Crystal structure of a bacterial type IB DNA topoisomerase reveals a preassembled active site in the absence of DNA.

21 January 2018

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Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove

21 January 2018

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Site-specific DNA transesterification by vaccinia topoisomerase: effects of benzo[alpha]pyrene-dA, 8-oxoguanine, 8-oxoadenine and 2-aminopurine modifications

21 January 2018

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Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase

21 January 2018

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Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III.

21 January 2018

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Major groove interactions of vaccinia Topo I provide specificity by optimally positioning the covalent phosphotyrosine linkage

21 January 2018

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Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pair

21 January 2018

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Selective pairing of polyfluorinated DNA bases

21 January 2018

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Active site tightness and substrate fit in DNA replication

21 January 2018

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Probing the requirements for recognition and catalysis in Fpg and MutY with nonpolar adenine isosteres

21 January 2018

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Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication

21 January 2018

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Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection

21 January 2018

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Mapping the active-site tyrosine of vaccinia virus DNA topoisomerase I.

21 January 2018

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DNA contacts stimulate catalysis by a poxvirus topoisomerase

21 January 2018

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Protein footprinting by the combined use of reversible and irreversible lysine modifications

21 January 2018

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Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding

21 January 2018

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Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167.

21 January 2018

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Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

21 January 2018

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Structural Basis for Specificity in the Poxvirus Topoisomerase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M608349200

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2 September 2017

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