A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay (Q38318734)

2 September 2017

A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay (English)

1 reference

2 September 2017

Stewart L

1

1 reference

2 September 2017

Ireton GC

series ordinal

2

1 reference

2 September 2017

Champoux JJ

series ordinal

3

1 reference

2 September 2017

language of work or name

English

0 references

publication date

1 November 1999

1 reference

Journal of Biological Chemistry

2 September 2017

1 reference

2 September 2017

274

1 reference

2 September 2017

46

1 reference

2 September 2017

32950-32960

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

2 September 2017

1 reference

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Shortening velocity of collagen and muscle fibers(1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Topoisomerase I inhibitors: review and update

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Diversity of DNA topoisomerases I and inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

A model for the mechanism of human topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Biochemical and biophysical analyses of recombinant forms of human topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

The domain organization of human topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Reconstitution of human topoisomerase I by fragment complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

A novel suicide substrate for DNA topoisomerases and site-specific recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Synthesis and selective cleavage of an oligodeoxynucleotide containing a bridged internucleotide 5'-phosphorothioate linkage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

DNA topoisomerase I-mediated formation of structurally modified DNA duplexes. Effects of metal ions and topoisomerase I inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Mapping of sequence-specific chromatin proteins by a novel method: topoisomerase I on Tetrahymena ribosomal chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Vaccinia DNA topoisomerase I: kinetic evidence for general acid-base catalysis and a conformational step

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Domains of human topoisomerase I and associated functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

Sequence-dependent effect of camptothecin on human topoisomerase I DNA cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32950

21 January 2018

Identifiers

DOI

10.1074/JBC.274.46.32950

1 reference

2 September 2017

1 reference