EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif. (Q38318791)

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English	EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif.	scientific article

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30 October 2019

EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif (English)

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30 October 2019

Epstein–Barr virus

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author name string

P D Ling

1

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30 October 2019

J J Ryon

2

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S D Hayward

3

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1 June 1993

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number of pages

14

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Journal of Virology

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30 October 2019

67

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6

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30 October 2019

2990-3003

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30 October 2019

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

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Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4.

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6 September 2017

Colinearity between the DNAs of Epstein-Barr virus and herpesvirus papio.

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U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2

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6 September 2017

DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

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6 September 2017

Nucleotide sequences of mRNAs encoding Epstein-Barr virus nuclear proteins: a probable transcriptional initiation site

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Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.

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Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: a potentially polycistronic message generated by long-range splicing of several exons

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Epstein-Barr virus (EBV) induces expression of B-cell activation markers on in vitro infection of EBV-negative B-lymphoma cells

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Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells

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A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus.

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Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation

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Responsiveness of the Epstein-Barr virus NotI repeat promoter to the Z transactivator is mediated in a cell-type-specific manner by two independent signal regions

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Influence of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virus

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6 September 2017

Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1.

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Detection of EBV gene expression in Reed-Sternberg cells of Hodgkin's disease

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Epstein-Barr virus-encoded nuclear antigen 2 activates the viral latent membrane protein promoter by modulating the activity of a negative regulatory element

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6 September 2017

Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes

1 reference

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6 September 2017

The level of c-fgr RNA is increased by EBNA-2, an Epstein-Barr virus gene required for B-cell immortalization

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237635

6 September 2017

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237635

6 September 2017

Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes

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6 September 2017

Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein.

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Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23.

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Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection

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Epstein-Barr virus nuclear protein 2 mutations define essential domains for transformation and transactivation

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6 September 2017

EBNA-2 transactivates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237635

6 September 2017

Functional domains of Epstein-Barr virus nuclear antigen EBNA-1.

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6 September 2017

Delineation of the cis-acting element mediating EBNA-2 transactivation of latent infection membrane protein expression

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6 September 2017

An Epstein-Barr virus nuclear protein 2 domain essential for transformation is a direct transcriptional activator

1 reference

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6 September 2017

Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA element

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The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signal

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The Epstein-Barr virus R transactivator (Rta) contains a complex, potent activation domain with properties different from those of VP16

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6 September 2017

Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter

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Biologic and antigenic characteristics of epstein-barr virus-related herpesviruses of chimpanzees and baboons

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6 September 2017

DNA sequencing with chain-terminating inhibitors

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6 September 2017

Influence of the Epstein-Barr virus nuclear antigen EBNA 2 on the growth phenotype of virus-transformed B cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237635

14 September 2017

Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=237635

14 September 2017

Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene

1 reference

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14 September 2017

Host cell and EBNA-2 regulation of Epstein-Barr virus latent-cycle promoter activity in B lymphocytes.

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14 September 2017

Properties of a baboon lymphotropic herpesvirus related to Epstein-Barr virus

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A putative transforming gene of Jijoye virus differs from that of Epstein-Barr virus prototypes

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Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes

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Epstein-Barr virus latent gene expression during the initiation of B cell immortalization

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Coinfection with A- and B-type Epstein-Barr virus in human immunodeficiency virus-positive subjects

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Epstein-Barr virus in AIDS-related primary central nervous system lymphoma

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Expression of Epstein-Barr virus nuclear antigen 2 in insect cells from a baculovirus vector

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Early events in Epstein-Barr virus infection of human B lymphocytes

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Critical structural elements of the VP16 transcriptional activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8388484

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear protein localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/8388484

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.67.6.2990-3003.1993

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30 October 2019

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30 October 2019

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