The natural carotenoid astaxanthin, a PPAR-α agonist and PPAR-γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes (Q38324364)

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English	The natural carotenoid astaxanthin, a PPAR-α agonist and PPAR-γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

The natural carotenoid astaxanthin, a PPAR-α agonist and PPAR-γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

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Yaoyao Jia

1

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2 September 2017

Jin-Young Kim

2

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2 September 2017

Hee-Jin Jun

3

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2 September 2017

Sun-Joong Kim

4

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2 September 2017

Ji-Hae Lee

5

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2 September 2017

Minh Hien Hoang

6

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2 September 2017

Kwang-Yeon Hwang

7

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2 September 2017

Soo-Jong Um

8

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2 September 2017

Hyo Ihl Chang

9

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2 September 2017

Sung-Joon Lee

10

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2 September 2017

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publication date

1 June 2012

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2 September 2017

Molecular Nutrition and Food Research

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2 September 2017

56

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2 September 2017

6

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2 September 2017

878-888

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2 September 2017

Integration of metabolism and inflammation by lipid-activated nuclear receptors

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https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

PPARs as therapeutic targets in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Peroxisome proliferator-activated receptor alpha in metabolic disease, inflammation, atherosclerosis and aging

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Peroxisome proliferators and peroxisome proliferator activated receptors (PPARs) as regulators of lipid metabolism

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

PPAR delta: a dagger in the heart of the metabolic syndrome

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https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

FDA puts rosiglitazone post-marketing trial on hold

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

The role of herbal PPAR modulators in the treatment of cardiometabolic syndrome

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https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy

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https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Astaxanthin, oxidative stress, inflammation and cardiovascular disease

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https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Astaxanthin: a potential therapeutic agent in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Inhibition of low-density lipoprotein oxidation by astaxanthin.

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https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Astaxanthin ameliorates features of metabolic syndrome in SHR/NDmcr-cp.

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Astaxanthin-rich extract from the green alga Haematococcus pluvialis lowers plasma lipid concentrations and enhances antioxidant defense in apolipoprotein E knockout mice.

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Barley intake induces bile acid excretion by reduced expression of intestinal ASBT and NPC1L1 in C57BL/6J mice

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Hypocholesterolemic and hypoglycemic effects of enzymatically modified carbohydrates from rice in high-fat-fed C57BL/6J mice.

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Limonene, a natural cyclic terpene, is an agonistic ligand for adenosine A(2A) receptors.

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Safety issues and prospects for future generations of PPAR modulators

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

PPAR dual agonists: are they opening Pandora's Box?

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

PPARalpha and PPARgamma dual agonists for the treatment of type 2 diabetes and the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators.

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Astaxanthin ameliorates the redox imbalance in lymphocytes of experimental diabetic rats

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Plasma appearance and distribution of astaxanthin E/Z and R/S isomers in plasma lipoproteins of men after single dose administration of astaxanthin.

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Docosahexaenoic acid induces adipose differentiation-related protein through activation of retinoid x receptor in human choriocarcinoma BeWo cells

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

High dose astaxanthin lowers blood pressure and increases insulin sensitivity in rats: are these effects interdependent?

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Reduced hepatic fatty acid oxidation in fasting PPARalpha null mice is due to impaired mitochondrial hydroxymethylglutaryl-CoA synthase gene expression.

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201100798

21 January 2018

Identifiers

10.1002/MNFR.201100798

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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