Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis (Q38333136)

2 September 2017

Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis (English)

1 reference

2 September 2017

Sylvie Garneau-Tsodikova

series ordinal

3

1 reference

2 September 2017

Kristin J Labby

1

1 reference

PubMed ID

25622971

2 September 2017

Stoyan G Watsula

series ordinal

2

1 reference

2 September 2017

1 May 2015

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2 September 2017

Natural Product Reports

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2 September 2017

32

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2 September 2017

5

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2 September 2017

641-653

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Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds

2 September 2017

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Cloning and characterization of the biosynthetic gene cluster for kutznerides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

In vitro reconstitution of the Pseudomonas aeruginosa nonribosomal peptide synthesis of pyochelin: characterization of backbone tailoring thiazoline reductase and N-methyltransferase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Biosynthesis of a complex yersiniabactin-like natural product via the mic locus in phytopathogen Ralstonia solanacearum

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Functional characterization of the recombinant N-methyltransferase domain from the multienzyme enniatin synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-polyketide synthetase system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Identification and analysis of the core biosynthetic machinery of tubulysin, a potent cytotoxin with potential anticancer activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Identification and partial characterization of the nonribosomal peptide synthetase gene responsible for cereulide production in emetic Bacillus cereus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

An indigoidine biosynthetic gene cluster from Streptomyces chromofuscus ATCC 49982 contains an unusual IndB homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

KtzJ-dependent serine activation and O-methylation by KtzH for kutznerides biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

The A9 core sequence from NRPS adenylation domain is relevant for thioester formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Nonribosomal peptides: from genes to products

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structure of a Eukaryotic Nonribosomal Peptide Synthetase Adenylation Domain That Activates a Large Hydroxamate Amino Acid in Siderophore Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Crystal structure and enantiomer selection by D-alanyl carrier protein ligase DltA from Bacillus cereus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

MbtH homology codes to identify gifted microbes for genome mining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Activation of the pacidamycin PacL adenylation domain by MbtH-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

The small MbtH-like protein encoded by an internal gene of the balhimycin biosynthetic gene cluster is not required for glycopeptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Effects of deletions of mbtH-like genes on clorobiocin biosynthesis in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Solution structure of Rv2377c-founding member of the MbtH-like protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

MbtH-like proteins as integral components of bacterial nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

N-acylation during glidobactin biosynthesis by the tridomain nonribosomal peptide synthetase module GlbF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Role of MbtH-like proteins in the adenylation of tyrosine during aminocoumarin and vancomycin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Production of mycobacterial cell wall glycopeptidolipids requires a member of the MbtH-like protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

A domain of RubC1 of rubradirin biosynthesis can functionally replace MbtH-like proteins in tyrosine adenylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Non-ribosomal propeptide precursor in nocardicin A biosynthesis predicted from adenylation domain specificity dependent on the MbtH family protein NocI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

In vitro characterization of echinomycin biosynthesis: formation and hydroxylation of L-tryptophanyl-S-enzyme and oxidation of (2S,3S) β-hydroxytryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Recent developments in bisintercalator natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

TioS T-TE--a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Kutznerides 1-4, depsipeptides from the actinomycete Kutzneria sp. 744 inhabiting mycorrhizal roots of Picea abies seedlings

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Biosynthesis of PF1022A and related cyclooctadepsipeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Genes encoding synthetases of cyclic depsipeptides, anabaenopeptilides, in Anabaena strain 90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Thaxtomin biosynthesis: the path to plant pathogenicity in the genus Streptomyces.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Heterologous expression and genetic engineering of the tubulysin biosynthetic gene cluster using Red/ET recombineering and inactivation mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Epothilone biosynthesis: assembly of the methylthiazolylcarboxy starter unit on the EpoB subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Biochemical characterization of MelJ and MelK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Characterization of indigoidine biosynthetic genes in Erwinia chrysanthemi and role of this blue pigment in pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Triggering the production of the cryptic blue pigment indigoidine from Photorhabdus luminescens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Production of the antimicrobial secondary metabolite indigoidine contributes to competitive surface colonization by the marine roseobacter Phaeobacter sp. strain Y4I

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Identification and characterization of an indigoidine-like gene for a blue pigment biosynthesis in Streptomyces aureofaciens CCM 3239.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Flavoenzymes: versatile catalysts in biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Engineering polyketide synthases and nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Structure guided approaches toward exploiting and manipulating nonribosomal peptide and polyketide biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Combinatorial biosynthesis of antibiotics: challenges and opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Combinatorial biosynthesis for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Combinatorial biosynthesis of novel antibiotics related to daptomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Active-site modifications of adenylation domains lead to hydrolysis of upstream nonribosomal peptidyl thioester intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Exploitation of the selectivity-conferring code of nonribosomal peptide synthetases for the rational design of novel peptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Directed evolution of the nonribosomal peptide synthetase AdmK generates new andrimid derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Adenylation and S-Methylation of Cysteine by the Bifunctional Enzyme TioN in Thiocoraline Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4NP00120F

Thiocoraline, a New Depsipeptide with Antitumor Activity Produced by a Marine Micromonospora. I. Taxonomy, Fermentation, Isolation, and Biological Activities.

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.50.734

Identifiers

DOI

10.1039/C4NP00120F

1 reference

2 September 2017

1 reference

PubMed ID

25622971