The MHC class II transactivator (CIITA) requires conserved leucine charged domains for interactions with the conserved W box promoter element. (Q38333945)

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English	The MHC class II transactivator (CIITA) requires conserved leucine charged domains for interactions with the conserved W box promoter element.	scientific article

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3 December 2019

The MHC class II transactivator (CIITA) requires conserved leucine charged domains for interactions with the conserved W box promoter element (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9722631%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Edward M. Rogers

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3 December 2019

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J A Brown

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3 December 2019

J M Boss

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3 December 2019

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1 September 1998

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3 December 2019

Nucleic Acids Research

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3 December 2019

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3 December 2019

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3 December 2019

4128-4136

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3 December 2019

Efficient repression of endogenous major histocompatibility complex class II expression through dominant negative CIITA mutants isolated by a functional selection strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

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6 September 2017

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1 reference

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6 September 2017

Regulatory factor X, a bare lymphocyte syndrome transcription factor, is a multimeric phosphoprotein complex

1 reference

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6 September 2017

Specific complex formation between the type II bare lymphocyte syndrome-associated transactivators CIITA and RFX5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Transactivation by CIITA, the type II bare lymphocyte syndrome-associated factor, requires participation of multiple regions of the TATA box binding protein

1 reference

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6 September 2017

The class II trans-activator CIITA interacts with the TBP-associated factor TAFII32

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants

1 reference

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6 September 2017

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency

1 reference

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6 September 2017

Constitutive c-ets2 expression in M1D+ myeloblast leukemic cells induces their differentiation to macrophages

1 reference

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6 September 2017

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1 reference

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6 September 2017

Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y

1 reference

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6 September 2017

Helix capping propensities in peptides parallel those in proteins

1 reference

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6 September 2017

Ectopic expression of wild-type or a dominant-negative mutant of transcription factor NTF-1 disrupts normal Drosophila development

1 reference

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6 September 2017

MHC class II-deficient combined immunodeficiency: a disease of gene regulation

1 reference

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6 September 2017

Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold

1 reference

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6 September 2017

Morphological and virological investigations on cultured Burkitt tumor lymphoblasts (strain Raji).

1 reference

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6 September 2017

B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

GTP-binding domain: three consensus sequence elements with distinct spacing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Conserved upstream sequences of human class II major histocompatibility genes enhance expression of class II genes in wild-type but not mutant B-cell lines

1 reference

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6 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Combined immunodeficiency with defective expression in MHC class II genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Regulation of major histocompatibility complex class-II genes: X, Y and other letters of the alphabet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Two B cell factors bind the HLA-DRA X box region and recognize different subsets of HLA class II promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits

1 reference

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6 September 2017

Sequences and factors: a guide to MHC class-II transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

6 September 2017

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

1 reference

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6 September 2017

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

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6 September 2017

Complex architecture of major histocompatibility complex class II promoters: reiterated motifs and conserved protein-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

14 September 2017

Suppression of MHC class II expression by human class II trans-activator constructs lacking the N-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

27 September 2017

Activation and transdominant suppression of MHC class II and HLA-DMB promoters by a series of C-terminal class II transactivator deletion mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

27 September 2017

CIITA-dependent and -independent class II MHC expression revealed by a dominant negative mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

27 September 2017

Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

27 September 2017

The GTP binding motif: variations on a theme

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27 September 2017

Regulation of transcription of MHC class II genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

27 September 2017

Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

27 September 2017

Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

27 September 2017

Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction

1 reference

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27 September 2017

Protease treatment of nuclear extracts distinguishes between class II MHC X1 box DNA-binding proteins in wild-type and class II-deficient B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

Class II MHC transcriptional mutants are defective in higher order complex formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

Human B cell variants immunoselected against a single Ia antigen subset have lost expression of several Ia antigen subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

Antigen-binding function of class II MHC molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

The W element is a positive regulator of HLA-DRA transcription in various DR+ cell types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

Genetic complexity of regulatory mutants defective for HLA class II gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

Reactivation of a major histocompatibility complex class II gene in mouse plasmacytoma cells and mouse T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

23 June 2018

Phosphorylation of the tumor suppressor adenomatous polyposis coli (APC) by the cyclin-dependent kinase p34.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

31 August 2018

Mouse class II transactivator: cDNA sequence and amino acid comparison with the human class II transactivator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

31 August 2018

Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

31 August 2018

Developmental and cytokine-mediated regulation of MHC class II gene promoter occupancy in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

31 August 2018

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147839

31 August 2018

In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis.

1 reference

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31 August 2018

A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes

1 reference

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31 August 2018

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1 reference

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31 August 2018

Defective HLA DRA X box binding in the class II transactive transcription factor mutant 6.1.6 and in cell lines from class II immunodeficient patients

1 reference

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31 August 2018

Formation of a regulatory factor X/X2 box-binding protein/nuclear factor-Y multiprotein complex on the conserved regulatory regions of HLA class II genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9722631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/9722631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single base pair substitutions within the HLA-DRA gene promoter separate the functions of the X1 and X2 boxes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9722631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9722631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA-DMA and HLA-DMB gene expression functions through the conserved S-X-Y region

1 reference

https://pubmed.ncbi.nlm.nih.gov/9722631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/9722631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1093/NAR/26.18.4128

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3 December 2019

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3 December 2019

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3 December 2019

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