Identification of SOCS-3 as a potential mediator of central leptin resistance (Q38335615)

2 September 2017

Identification of SOCS-3 as a potential mediator of central leptin resistance (English)

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2 September 2017

5

J S Flier

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2 September 2017

C Bjørbaek

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2 September 2017

J K Elmquist

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2

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2 September 2017

J D Frantz

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3

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2 September 2017

S E Shoelson

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4

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2 September 2017

1 March 1998

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2 September 2017

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2 September 2017

1

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2 September 2017

619-625

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2 September 2017

4

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Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

2 September 2017

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Role of leptin in the neuroendocrine response to fasting

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Divergent signaling capacities of the long and short isoforms of the leptin receptor

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Independent and additive effects of central POMC and leptin pathways on murine obesity.

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Systemic interleukin-1 induces early and late patterns of c-fos mRNA expression in brain.

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Molecular characterization of the mouse agouti locus.

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Mutations at the agouti locus in the mouse

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei.

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Leptin activates neurons in ventrobasal hypothalamus and brainstem

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Defective STAT signaling by the leptin receptor in diabetic mice

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Weight-reducing effects of the plasma protein encoded by the obese gene

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Abnormal splicing of the leptin receptor in diabetic mice

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Cloning and characterization of novel CIS family genes

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Effects of the obese gene product on body weight regulation in ob/ob mice

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Melanocortin receptors in leptin effects.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

A family of cytokine-inducible inhibitors of signalling

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

The role of neuropeptide Y in the antiobesity action of the obese gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Identification and expression cloning of a leptin receptor, OB-R

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Crystal structure of the obese protein leptin-E100

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980062-3

7 January 2021

10.1016/S1097-2765(00)80062-3

Identifiers

DOI

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2 September 2017

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