Comparative, general pharmacology of SDZ NKT 343, a novel, selective NK1 receptor antagonist. (Q38336515)

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12 November 2019

title

Comparative, general pharmacology of SDZ NKT 343, a novel, selective NK1 receptor antagonist (English)

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5

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author name string

Walpole CS

1

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Brown MC

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James IF

3

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Campbell EA

4

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Docherty R

6

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Ko S

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Hedley L

8

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Ewan S

9

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Buchheit KH

10

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Urban LA

11

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language of work or name

English

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publication date

1 May 1998

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British Journal of Pharmacology

12 November 2019

published in

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volume

124

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issue

1

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page(s)

83-92

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The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist

12 November 2019

cites work

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Higher potency of RP 67580, in the mouse and the rat compared with other nonpeptide and peptide tachykinin NK1 antagonists

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Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345

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Block of voltage-dependent sodium currents by the substance P receptor antagonist (+/-)-CP-96,345 in neurones cultured from rat cortex

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Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia.

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Pharmacological profile of a high affinity dipeptide NK1 receptor antagonist, FK888

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The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040

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The interaction of the NK1 receptor antagonist CP‐96,345 with L‐type calcium channels and its functional consequences

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Non-specific activity of (+/-)-CP-96,345 in models of pain and inflammation

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Non-specific actions of the non-peptide tachykinin receptor antagonists, CP-96,345, RP 67580 and SR 48968, on neurotransmission

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Modulation of neurogenic inflammation: novel approaches to inflammatory disease

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Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergic airway disease

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Cloning, expression of the human substance K receptor, and analysis of its role in mitogenesis

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Biochemical properties of rat protein kinase C-eta expressed in COS cells

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New pharmacological strategies for pain relief

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Experimental headache models in animals and humans

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In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist

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Pharmacological properties of a potent and selective nonpeptide substance P antagonist

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Differential sensitivity of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels to the insecticide allethrin in rat dorsal root ganglion neurons.

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Species differences in affinities of non-peptide antagonists for substance p receptors

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Participation of substance P in spinal physiological responses to peripheral aversive stimulation

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Measurement of intracellular calcium in cell populations loaded with aequorin: neurokinin-1 responses in U373MG cells.

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cDNA sequence and heterologous expression of the human neurokinin-3 receptor

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Pathophysiology of joint pain

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Differential effects of non-peptidic tachykinin receptor antagonists on Ca2+ channels

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LIGAND: A versatile computerized approach for characterization of ligand-binding systems

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A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) Receptor

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Molecular cloning, structural characterization and functional expression of the human substance P receptor

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Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.

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Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- and C-fiber mediated responses in the rat spinal cord in vitro

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Identifiers

DOI

10.1038/SJ.BJP.0701806

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12 November 2019

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12 November 2019

PubMed publication ID

9630347

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