Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues. (Q38342150)

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English	Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues.	scientific article

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27 December 2019

Degradation, receptor binding, insulin secreting and antihyperglycaemic actions of palmitate-derivatised native and Ala8-substituted GLP-1 analogues (English)

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27 December 2019

Clifford J Bailey

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27 December 2019

Victor A. Gault

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27 December 2019

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27 December 2019

Finbarr O'Harte

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27 December 2019

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27 December 2019

Patrick Harriott

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Patrick Harriott

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27 December 2019

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Mark H Mooney

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27 December 2019

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Brian D Green

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27 December 2019

Brett Greer

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27 December 2019

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1 February 2004

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27 December 2019

Biological Chemistry

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27 December 2019

385

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27 December 2019

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27 December 2019

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27 December 2019

The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in noninsulin-dependent diabetes mellitus.

1 reference

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21 January 2018

Long-lasting antidiabetic effect of a dipeptidyl peptidase IV-resistant analog of glucagon-like peptide-1.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: retention of NN304 by albumin

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Synthesis of palmitoyl derivatives of insulin and their biological activities

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

In vivo dynamic distribution of 131I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Glucagon-like peptide-1 7-36: a physiological incretin in man.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats.

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitate

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

NN2211: a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

1 reference

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21 January 2018

A role for glucagon-like peptide-1 in the central regulation of feeding

1 reference

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21 January 2018

Glucagon-like peptide 1: a potent glycogenic hormone

1 reference

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21 January 2018

Subcutaneous Injection of the Incretin Hormone Glucagon-Like Peptide 1 Abolishes Postprandial Glycemia in NIDDM

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

The Inhibitory Effect of Glucagon-Like Peptide-1 (7-36)amide on Antral Motility is Antagonized by Its N-Terminally Truncated Primary Metabolite GLP-1 (9-36)amide

1 reference

https://api.crossref.org/works/10.1515%2FBC.2004.035

21 January 2018

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10.1515/BC.2004.035

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15101559%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

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Europe PubMed Central

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27 December 2019

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