Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing (Q38346151)

2 September 2017

Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing (English)

1 reference

2 September 2017

Markus Riessland

3

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Thorsten Buch

object named as

Thorsten Buch

8

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André Kleinridders

object named as

André Kleinridders

6

0 references

author name string

Ylva Mende

1

1 reference

2 September 2017

Miriam Jakubik

2

1 reference

2 September 2017

Frank Schoenen

4

1 reference

2 September 2017

Kristina Rossbach

5

1 reference

2 September 2017

Christoph Köhler

7

1 reference

2 September 2017

Brunhilde Wirth

9

1 reference

2 September 2017

language of work or name

1 reference

27 February 2010

1 reference

2 September 2017

Human Molecular Genetics

1 reference

2 September 2017

19

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2 September 2017

11

1 reference

2 September 2017

2154-2167

1 reference

Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing

2 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

A sequence-specific splicing activator, tra2beta, is up-regulated in response to nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Activity-dependent regulation of alternative splicing patterns in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Expression of a novel RNA-splicing factor, RA301/Tra2beta, in vascular lesions and its role in smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Molecular cloning of a mouse homologue for the Drosophila splicing regulator Tra2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Function of alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Tra2betal regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Regulation of the neuron-specific exon of clathrin light chain B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Tra2beta as a novel mediator of vascular smooth muscle diversification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Alternative splicing of fibroblast growth factor receptors in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Structure and organization of the human survival motor neurone (SMN) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

When is a deletion not a deletion? When it is converted

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Mildly affected patients with spinal muscular atrophy are partially protected by an increased SMN2 copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Spinal muscular atrophy: from gene to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Valproic acid increases SMN levels in spinal muscular atrophy patient cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Sex in flies: the splice of life

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Complete nucleotide sequence, genomic organization, and promoter analysis of the murine survival motor neuron gene (Smn).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

A mouse model for spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Animal models of spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

SC35 plays a role in T cell development and alternative splicing of CD45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Regulation of murine survival motor neuron (Smn) protein levels by modifying Smn exon 7 splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Correction of disease-associated exon skipping by synthetic exon-specific activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Simplified mammalian DNA isolation procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

21 January 2018

Identifiers

DOI

10.1093/HMG/DDQ094

1 reference

2 September 2017

1 reference