E2F1 represses beta-catenin/TCF activity by direct up-regulation of Siah1. (Q38346191)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20187294%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

E2F1 represses beta-catenin/TCF activity by direct up-regulation of Siah1 (English)

1 reference

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18 January 2020

2

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18 January 2020

Dr Mian Wu

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20187294%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Wei Xie

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20187294%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Yide Mei

series ordinal

3

1 reference

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18 January 2020

publication date

1 August 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20187294%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular and Molecular Medicine

18 January 2020

published in

1 reference

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18 January 2020

volume

13

1 reference

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18 January 2020

issue

8B

1 reference

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18 January 2020

page(s)

1719-1727

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Regulation of cell proliferation by the E2F transcription factors

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

E2F1 pathways to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Characterization of human homologs of the Drosophila seven in absentia (sina) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

A binding motif for Siah ubiquitin ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Regulation of BOB.1/OBF.1 stability by SIAH

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

SIAH-1 interacts with alpha-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Proteasomal regulation of nuclear receptor corepressor-mediated repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Siah-1 binds and regulates the function of Numb

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

The characterization of the human Siah-1 promoter(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

The E2F transcription factor is a cellular target for the RB protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

E2F Transcription Factor Is a Target for the RB Protein and the Cyclin A Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Linking colorectal cancer to Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Cross-talk between pRb/E2F and Wnt/beta-catenin pathways: E2F1 induces axin2 leading to repression of Wnt signalling and to increased cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

HIF-1 and tumor progression: pathophysiology and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Siah-1 facilitates ubiquitination and degradation of factor inhibiting HIF-1alpha (FIH).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2008.00423.X

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

21 January 2018

1 reference

12 December 2020

Wnt signaling and cancer

1 reference

12 December 2020

HIF-1 and human disease: one highly involved factor

1 reference

12 December 2020

Alteration of the stability of Bag-1 protein in the control of olfactory neuronal apoptosis

1 reference

12 December 2020

Flavopiridol-induced apoptosis is mediated through up-regulation of E2F1 and repression of Mcl-1.

1 reference

12 December 2020

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

12 December 2020

Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina).

1 reference

12 December 2020

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

12 December 2020

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

12 December 2020

10.1111/J.1582-4934.2008.00423.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20187294%20AND%20SRC:MED&resulttype=core&format=json

release_ysy2rix4tnev3djoivlnle23ui

18 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ysy2rix4tnev3djoivlnle23ui

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20187294%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference