Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma. (Q38351760)

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4 February 2020

title

Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma (English)

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4 February 2020

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7

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author name string

Fatoumata B Sow

1

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4 February 2020

Gail R Alvarez

2

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4 February 2020

Ryan P Gross

3

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4 February 2020

Abhay R Satoskar

4

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4 February 2020

Larry S Schlesinger

5

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4 February 2020

Bruce S Zwilling

6

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publication date

3 August 2009

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Journal of Leukocyte Biology

4 February 2020

published in

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4 February 2020

volume

86

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issue

5

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4 February 2020

page(s)

1247-1258

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Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

4 February 2020

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STATs: signal transducers and activators of transcription

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Cellular responses to interferon-gamma

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LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

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Effect of hepcidin on intestinal iron absorption in mice.

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Inhibition of iron transport across human intestinal epithelial cells by hepcidin

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Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin

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Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

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Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

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A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

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Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

21 January 2018

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The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

21 January 2018

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IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

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Regulation of hepcidin transcription by interleukin-1 and interleukin-6.

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Interleukin-6 induces hepcidin expression through STAT3

21 January 2018

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C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism

21 January 2018

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TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens

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Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis.

21 January 2018

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Toll-like receptor 2 stimulation decreases IFN-gamma receptor expression in mouse RAW264.7 macrophages.

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Mycobacterium tuberculosis and Mycobacterium avium inhibit IFN- gamma -induced gene expression by TLR2-dependent and independent pathways.

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice

21 January 2018

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Toll-like receptor signalling

21 January 2018

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Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

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The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity Functions

21 January 2018

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Distribution of the iron-regulating protein hepcidin in the murine central nervous system.

21 January 2018

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Hepcidin expression in mouse retina and its regulation via lipopolysaccharide/Toll-like receptor-4 pathway independent of Hfe.

21 January 2018

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Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors.

21 January 2018

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ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma

21 January 2018

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MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma

21 January 2018

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C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages

21 January 2018

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CCAAT/enhancer binding proteins and interferon signaling pathways

21 January 2018

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The promoter of IL-18 binding protein: activation by an IFN-gamma -induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein beta

21 January 2018

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The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor

21 January 2018

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Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6

21 January 2018

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A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

21 January 2018

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Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9.

21 January 2018

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The distal location of the iron responsive region of the hepcidin promoter.

21 January 2018

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Identifiers

DOI

10.1189/JLB.1208719

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19652026%20AND%20SRC:MED&resulttype=core&format=json

release_y3gekm4cjjhqbbmvadrxzjqu4a

4 February 2020

Fatcat ID

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mapped directly with Wikidata item

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