Identification of genes that confer tumor cell resistance to the aurora B kinase inhibitor, AZD1152. (Q38356907)

2 September 2017

Identification of genes that confer tumor cell resistance to the aurora B kinase inhibitor, AZD1152. (English)

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2 September 2017

J Guo

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M G Anderson

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P Tapang

3

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J P Palma

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L E Rodriguez

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A Niquette

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J Li

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J J Bouska

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G Wang

9

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D Semizarov

10

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D H Albert

11

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C K Donawho

12

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K B Glaser

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O J Shah

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3 February 2009

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The Pharmacogenomics Journal

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9

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2

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90-102

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https://scigraph.springernature.com/pub.10.1038/tpj.2008.20

2 September 2017

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Mitotic mechanics: the auroras come into view

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

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VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

21 January 2018

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

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Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

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Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase

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AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis

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Strategies for overcoming p-glycoprotein-mediated drug resistance in acute myeloblastic leukaemia

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The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis

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Molecular basis of drug resistance in aurora kinases

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MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping

21 January 2018

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Cross-talk between signalling pathways and the multidrug resistant protein MDR-1

21 January 2018

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The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function

21 January 2018

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Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines

21 January 2018

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Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance

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A multidrug resistance transporter from human MCF-7 breast cancer cells

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Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor

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Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells

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ABCG2 expression, function, and promoter methylation in human multiple myeloma

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Integrative genomic analysis of small-cell lung carcinoma reveals correlates of sensitivity to bcl-2 antagonists and uncovers novel chromosomal gains

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/TPJ.2008.20

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Dimensions Publication ID

2 September 2017

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