Beta-aminoisobutyric acid prevents diet-induced obesity in mice with partial leptin deficiency (Q38356934)

2 September 2017

Beta-aminoisobutyric acid prevents diet-induced obesity in mice with partial leptin deficiency (English)

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2 September 2017

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3-aminoisobutyric acid

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ChEBI release 2020-05-28

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2 September 2017

Karima Begriche

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2 September 2017

Adjé Abbey-Toby

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2 September 2017

Anissa Igoudjil

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2 September 2017

Philippe Lettéron

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2 September 2017

Bernard Fromenty

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2 September 2017

1 September 2008

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2 September 2017

2053-2067

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Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it.

2 September 2017

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Drug treatments for obesity: orlistat, sibutramine, and rimonabant.

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Fatty acid metabolism as a target for obesity treatment

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Mitochondrial and metabolic effects of nucleoside reverse transcriptase inhibitors (NRTIs) in mice receiving one of five single- and three dual-NRTI treatments

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Leptin and the regulation of body weight in mammals

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Alcohol increases tumor necrosis factor alpha and decreases nuclear factor-kappab to activate hepatic apoptosis in genetically obese mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Leptin is essential for the hepatic fibrogenic response to chronic liver injury

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

The stomach is a source of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Interrelation between long-chain fatty acid oxidation rate and carnitine palmitoyltransferase 1 activity with different isoforms in rat tissues

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Gastric leptin: a new manager of gastrointestinal function.

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Liver triglyceride secretion and lipid oxidative metabolism are rapidly altered by leptin in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in diet-induced obesity

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Regulation of leptin secretion from white adipocytes by insulin, glycolytic substrates, and amino acids.

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

The role of leptin resistance in the lipid abnormalities of aging.

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Short term effects of leptin on hepatic gluconeogenesis and in vivo insulin action.

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Leptin improves insulin resistance and hyperglycemia in a mouse model of type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Metabolic, hormonal, oxidative, and inflammatory factors in pediatric obesity-related liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Relatively low plasma leptin concentrations precede weight gain in Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Partial leptin deficiency and human adiposity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Beta-amino acids: mammalian metabolism and utility as alpha-amino acid analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

A polymorphism in the leptin promoter region (-2548 G/A) influences gene expression and adipose tissue secretion of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Obesity as a medical problem

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Serum lipoprotein and apolipoprotein profiles of the genetically obese ob/ob mouse

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Cytochrome P4502B follows a vesicular route to the plasma membrane in cultured rat hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Cell-generated nitric oxide inactivates rat hepatocyte mitochondria in vitro but reacts with hemoglobin in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Response to intra- and extracellular lipolytic agents and hormone-sensitive lipase translocation are impaired in adipocytes from rats adapted to a high-protein, carbohydrate-free diet

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Differential regulation of leptin expression and function in A/J vs. C57BL/6J mice during diet-induced obesity

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent.

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

A new role for leptin as a direct satiety signal from the stomach

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Transcytosis of gastric leptin through the rat duodenal mucosa

31 March 2020

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https://api.crossref.org/works/10.1038%2FOBY.2008.337

Acute effects of leptin on glucose metabolism of in situ rat perfused livers and isolated hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Effects of volatile fatty acids and ketone bodies on lipolysis in isolated adipocytes from Norwegian reindeer (Rangifer tarandus)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

A pivotal role for beta-aminoisobutyric acid and oxidative stress in dihydropyrimidine dehydrogenase deficiency?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Obese (ob) gene defects are rare in human obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Novel polymorphisms in the 5' region of the LEP gene: association with leptin levels and response to low-calorie diet in human obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

Physiological role of cholecystokinin B/gastrin receptor in leptin secretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2008.337

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7 January 2021

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Identifiers

DOI

10.1038/OBY.2008.337

1 reference

2 September 2017

1 reference