Involvement of multidrug resistance proteins (MDR) in the modulation of glucocorticoid response (Q38357628)

2 September 2017

title

Involvement of multidrug resistance proteins (MDR) in the modulation of glucocorticoid response (English)

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2 September 2017

main subject

multiple drug resistance

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Jeanette I Webster

1

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2 September 2017

Jan Carlstedt-Duke

series ordinal

2

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2 September 2017

publication date

1 November 2002

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The Journal of Steroid Biochemistry and Molecular Biology

2 September 2017

published in

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2 September 2017

volume

82

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2 September 2017

issue

4-5

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2 September 2017

page(s)

277-288

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Molecular mechanisms of glucocorticoid resistance

2 September 2017

cites work

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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

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Do cMOAT (MRP2), other MRP homologues, and LRP play a role in MDR?

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Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

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Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

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Cloning and characterization of a second member of the mouse mdr gene family

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7 January 2021

The active transport of cortisol by mouse fibroblasts growing in vitro

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7 January 2021

Steroid treatment, accumulation, and antagonism of P-glycoprotein in multidrug-resistant cells.

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7 January 2021

Cortisol is transported by the multidrug resistance gene product P-glycoprotein

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7 January 2021

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

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Profound differences in the transport of steroids by two mouse P-glycoproteins

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Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil

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7 January 2021

Reversal of multidrug resistance by an immunosuppressive agent FK-506

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7 January 2021

ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): no inhibition by intracellular glutathione depletion.

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7 January 2021

Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells

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7 January 2021

Characterization and inhibition by a wide range of xenobiotics of organic anion excretion by primary human hepatocytes

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7 January 2021

Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p

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7 January 2021

An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones

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Active efflux by multidrug transporters as one of the strategies to evade chemotherapy and novel practical implications of yeast pleiotropic drug resistance

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7 January 2021

Dexamethasone and triamcinolone acetonide accumulation in mouse fibroblasts is differently modulated by the immunosuppressants cyclosporin A, FK506, rapamycin and their analogues, as well as by other P-glycoprotein ligands

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7 January 2021

Agonist-specific modulation of glucocorticoid receptor-mediated transcription by immunosuppressants.

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7 January 2021

Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/Stat 5.

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Comparative evaluation by semiquantitative reverse transcriptase polymerase chain reaction of MDR1, MRP and GSTp gene expression in breast carcinomas

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7 January 2021

Flow cytometric analysis of P-glycoprotein function using rhodamine 123

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7 January 2021

Functional characterization of the rat mdr1b encoded P-glycoprotein: not all inducing agents are substrates

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7 January 2021

Calcein accumulation as a fluorometric functional assay of the multidrug transporter

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7 January 2021

Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein

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7 January 2021

Using the national cancer institute anticancer drug screen to assess the effect of MRP expression on drug sensitivity profiles

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7 January 2021

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

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P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors

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7 January 2021

Interaction of the progesterone receptor with binding proteins for FK506 and cyclosporin A.

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7 January 2021

Effects of immunosuppressants FK506 and rapamycin on the heterooligomeric form of the progesterone receptor

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7 January 2021

Cyclosporin A, FK506 and rapamycin: more than just immunosuppression

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7 January 2021

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

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7 January 2021

P-glycoprotein transports corticosterone and is photoaffinity-labeled by the steroid

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7 January 2021

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7 January 2021

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7 January 2021

Interaction of glucocorticoid receptor isoforms with transcription factors AP-1 and NF-kappaB: lack of effect of glucocorticoid receptor beta.

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7 January 2021

Glucocorticoid Receptor beta: View II

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7 January 2021

Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor

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7 January 2021

Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta

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7 January 2021

Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma.

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7 January 2021

Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor beta-isoform

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7 January 2021

Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis

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7 January 2021

Role of multidrug resistance P-glycoprotein in the secretion of aldosterone by human adrenal NCI-H295 cells

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7 January 2021

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Identifiers

DOI

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2 September 2017

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