The interleukin-6 (IL-6) partial antagonist (Q159E,T162P)IL-6 interacts with the IL-6 receptor and gp130 but fails to induce a stable hexameric receptor complex (Q38360612)

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English	The interleukin-6 (IL-6) partial antagonist (Q159E,T162P)IL-6 interacts with the IL-6 receptor and gp130 but fails to induce a stable hexameric receptor complex	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

The interleukin-6 (IL-6) partial antagonist (Q159E,T162P)IL-6 interacts with the IL-6 receptor and gp130 but fails to induce a stable hexameric receptor complex (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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author name string

Hammacher A

1

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Europe PubMed Central

PubMed publication ID

2 September 2017

Simpson RJ

2

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PubMed publication ID

2 September 2017

Nice EC

3

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Europe PubMed Central

PubMed publication ID

2 September 2017

language of work or name

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publication date

1 March 1996

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Europe PubMed Central

PubMed publication ID

2 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

2 September 2017

271

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Europe PubMed Central

PubMed publication ID

2 September 2017

10

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Europe PubMed Central

PubMed publication ID

2 September 2017

5464-5473

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Molecular cloning and expression of an IL-6 signal transducer, gp130

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Cytokine signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Structure-function analysis of human IL-6: identification of two distinct regions that are important for receptor binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Analysis of macromolecular interactions using immobilized ligands.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: use of nonlinear least squares analysis methods.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Interpreting complex binding kinetics from optical biosensors: a comparison of analysis by linearization, the integrated rate equation, and numerical integration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Role of the C-terminus in the activity, conformation, and stability of interleukin-6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Purification and characterization of soluble human IL-6 receptor expressed in CHO cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Association of recombinant soluble IL-6-signal transducer, gp130, with a complex of IL 6 and soluble IL-6 receptor, and establishment of an ELISA for soluble gp130

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Use of a biosensor with surface plasmon resonance detection for the determination of binding constants: measurement of interleukin-6 binding to the soluble interleukin-6 receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Determination of relative binding affinity of influenza virus N9 sialidases with the Fab fragment of monoclonal antibody NC41 using biosensor technology

1 reference

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21 January 2018

Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Kinetics of p56lck and p60src Src homology 2 domain binding to tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Purification and characterization of a recombinant murine interleukin-6. Isolation of N- and C-terminally truncated forms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Synergies between micropreparative high-performance liquid chromatography and an instrumental optical biosensor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Surface plasmon resonance based methods for measuring the kinetics and binding affinities of biomolecular interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5464

21 January 2018

Identifiers

10.1074/JBC.271.10.5464

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

ResearchGate publication ID

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