PDX-1 mediates glucose responsiveness of GAD(67), but not GAD(65), gene transcription in islets of Langerhans (Q38363895)

2 September 2017

PDX-1 mediates glucose responsiveness of GAD(67), but not GAD(65), gene transcription in islets of Langerhans (English)

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2 September 2017

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Anette Amstrup Pedersen

1

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2 September 2017

Helle Vestergaard Petersen

2

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2 September 2017

Nicoline Videbaek

3

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2 September 2017

Kresten Skak

4

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2 September 2017

Birgitte Koch Michelsen

5

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2 September 2017

language of work or name

English

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publication date

1 July 2002

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Biochemical and Biophysical Research Communications

2 September 2017

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2 September 2017

295

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2 September 2017

2

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2 September 2017

243-248

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Two forms of rat brain glutamic acid decarboxylase differ in their dependence on free pyridoxal phosphate.

2 September 2017

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Evidence for two distinct forms of native glutamic acid decarboxylase in rat brain soluble extract: an immunoblotting study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Kinetically different, multiple forms of glutamate decarboxylase in rat brain.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Expression of the 64 kDa/glutamic acid decarboxylase rat islet cell autoantigen is influenced by the rate of insulin secretion

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Functional state of the beta cell affects expression of both forms of glutamic acid decarboxylase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Regulation of GAD expression in rat pancreatic islets and brain by gamma-vinyl-GABA and glucose.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals

7 January 2021

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Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy

7 January 2021

1 reference

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Diazoxide treatment at onset preserves residual insulin secretion in adults with autoimmune diabetes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

The TATA-less rat GAD65 promoter can be activated by Sp1 through non-consensus elements

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Characterization of the rat GAD67 gene promoter reveals elements important for basal transcription and glucose responsiveness

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Insulin-promoter-factor 1 is required for pancreas development in mice

7 January 2021

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The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Cloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene

7 January 2021

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Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic alpha cells

7 January 2021

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Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Regulatory properties of brain glutamate decarboxylase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

High Concentration of GABA and High Glutamate Decarboxylase Activity in Rat Pancreatic Islets and Human Insulinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Immunoreactive GABA transaminase within the pancreatic islet is localized in mitochondria of the B-cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization, and evolutionary history

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2900674-5

10.1016/S0006-291X(02)00674-5

7 January 2021

Identifiers

DOI

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2 September 2017

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