Remyelination in multiple sclerosis: what do we know and where are we going? (Q38364826)

2 September 2017

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title

Remyelination in multiple sclerosis: what do we know and where are we going? (English)

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2 September 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25711454%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Anna Williams

series ordinal

1

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2 September 2017

1 January 2015

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Neurodegenerative disease management

2 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25711454%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25711454%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

49-59

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25711454%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25711454%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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Pathology of multiple sclerosis and related inflammatory demyelinating diseases

21 January 2018

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Evidence of early cortical atrophy in MS: relevance to white matter changes and disability.

21 January 2018

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Evidence for saltatory conduction in peripheral myelinated nerve fibres

21 January 2018

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Oligodendroglia metabolically support axons and contribute to neurodegeneration.

21 January 2018

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Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions

21 January 2018

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Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis

21 January 2018

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Mitochondrial changes within axons in multiple sclerosis

21 January 2018

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Mitochondrial defects in acute multiple sclerosis lesions

21 January 2018

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Multiple sclerosis: an immune or neurodegenerative disorder?

21 January 2018

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Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis.

21 January 2018

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Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis

21 January 2018

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Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.

21 January 2018

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A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis.

21 January 2018

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Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords.

21 January 2018

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Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: an in vivo [(11)C](R)-PK11195-PET pilot study.

21 January 2018

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In Vivo Detection of Diffuse Inflammation in Secondary Progressive Multiple Sclerosis Using PET Imaging and the Radioligand ¹¹C-PK11195.

21 January 2018

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Pathological abnormalities in the normal-appearing white matter in multiple sclerosis

21 January 2018

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M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

21 January 2018

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Electron microscopic features of multiple sclerosis lesions

21 January 2018

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Remyelination is extensive in a subset of multiple sclerosis patients.

21 January 2018

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Remyelination can be extensive in multiple sclerosis despite a long disease course

21 January 2018

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Demyelination versus remyelination in progressive multiple sclerosis.

21 January 2018

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Extensive cortical remyelination in patients with chronic multiple sclerosis.

21 January 2018

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Remyelination capacity of the MS brain decreases with disease chronicity

21 January 2018

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Oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination

21 January 2018

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Multiple sclerosis. Pathology of recurrent lesions.

21 January 2018

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Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial

21 January 2018

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Targeted ablation of oligodendrocytes triggers axonal damage

21 January 2018

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Axonal swellings and degeneration in mice lacking the major proteolipid of myelin.

21 January 2018

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Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination

21 January 2018

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Remyelination protects axons from demyelination-associated axon degeneration

21 January 2018

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Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis.

21 January 2018

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Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).

21 January 2018

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Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

21 January 2018

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LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

21 January 2018

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Human remyelination promoting antibody inhibits apoptotic signaling and differentiation through Lyn kinase in primary rat oligodendrocytes

21 January 2018

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Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis

21 January 2018

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A regenerative approach to the treatment of multiple sclerosis

21 January 2018

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Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

21 January 2018

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Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

21 January 2018

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FTY720 modulates human oligodendrocyte progenitor process extension and survival.

21 January 2018

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Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices.

21 January 2018

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Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model

21 January 2018

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Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide.

21 January 2018

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Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis

21 January 2018

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Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

21 January 2018

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Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions.

21 January 2018

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Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse

21 January 2018

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Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis

21 January 2018

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Modulation of autoimmune demyelination by laquinimod via induction of brain-derived neurotrophic factor.

21 January 2018

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Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination

21 January 2018

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CNS axons retain their competence for myelination throughout life.

21 January 2018

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Intracerebral human regulatory T cells: analysis of CD4+ CD25+ FOXP3+ T cells in brain lesions and cerebrospinal fluid of multiple sclerosis patients.

21 January 2018

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Curing CNS autoimmune disease with myelin-reactive Foxp3+ Treg

21 January 2018

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Astrocytes--friends or foes in multiple sclerosis?

21 January 2018

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White matter astrocytes in health and disease

21 January 2018

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Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor

21 January 2018

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Astrocyte-derived endothelin-1 inhibits remyelination through notch activation

21 January 2018

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Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

21 January 2018

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Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease

21 January 2018

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Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system

21 January 2018

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Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects

21 January 2018

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Derivation of oligodendrocyte progenitor cells from human embryonic stem cells

21 January 2018

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High yields of oligodendrocyte lineage cells from human embryonic stem cells at physiological oxygen tensions for evaluation of translational biology.

21 January 2018

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Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination

21 January 2018

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Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis.

21 January 2018

1 reference

The therapeutic plasticity of neural stem/precursor cells in multiple sclerosis

21 January 2018

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Mesenchymal stem cells in health and disease

21 January 2018

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Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

21 January 2018

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Retinoid X receptor gamma signaling accelerates CNS remyelination

21 January 2018

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Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.

21 January 2018

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Intranasal delivery of cells to the brain.

21 January 2018

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Intranasal Delivery of Neural Stem Cells: A CNS-specific, Non-invasive Cell-based Therapy for Experimental Autoimmune Encephalomyelitis

21 January 2018

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Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain

21 January 2018

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Primary progressive multiple sclerosis: progress and challenges.

21 January 2018

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LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

21 January 2018

1 reference

NIR-labeled nanoparticles engineered for brain targeting: in vivo optical imaging application and fluorescent microscopy evidences

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/NMT.14.40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25711454%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference