The role of neuroinflammation in dementias (Q38365247)

2 September 2017

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title

The role of neuroinflammation in dementias (English)

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2 September 2017

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Giuseppe Pasqualetti

1

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2 September 2017

David J Brooks

series ordinal

2

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2 September 2017

Paul Edison

series ordinal

3

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2 September 2017

1 April 2015

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Current Neurology and Neuroscience Reports

2 September 2017

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2 September 2017

15

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2 September 2017

4

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2 September 2017

17

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https://scigraph.springernature.com/pub.10.1007/s11910-015-0531-7

2 September 2017

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Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

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Inflammatory risk factors and pathologies associated with Alzheimer's disease

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Expression of the histocompatibility glycoprotein HLA-DR in neurological disease

21 January 2018

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Cytokine production of activated microglia and decrease in neurotrophic factors of neurons in the hippocampus of Lewy body disease brains.

21 January 2018

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Common inflammatory mechanisms in Lewy body disease and Alzheimer disease

21 January 2018

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Microglia: active sensor and versatile effector cells in the normal and pathologic brain

21 January 2018

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Microglia: a sensor for pathological events in the CNS

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Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation.

21 January 2018

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M-1/M-2 macrophages and the Th1/Th2 paradigm

21 January 2018

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Microglia and neurodegeneration: the role of systemic inflammation.

21 January 2018

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Neuroinflammation: the role and consequences

21 January 2018

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Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.

21 January 2018

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Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation and learning and memory deficits.

21 January 2018

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Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice

21 January 2018

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NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

21 January 2018

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Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.

21 January 2018

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Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease

21 January 2018

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Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

21 January 2018

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Systemic Inflammation Modulates Fc Receptor Expression on Microglia during Chronic Neurodegeneration

21 January 2018

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Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

21 January 2018

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Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

The alpha-synuclein burden hypothesis of Parkinson disease and its relationship to Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

21 January 2018

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Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1beta in the substantia nigra.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Neuroinflammation and neuronal loss precede Aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Cyclooxygenase-1-dependent prostaglandins mediate susceptibility to systemic inflammation-induced acute cognitive dysfunction

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

p38 kinase is activated in the Alzheimer's disease brain.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Insulin reverses the high-fat diet-induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model

21 January 2018

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Peripheral administration of an anti-TNF-α receptor fusion protein counteracts the amyloid induced elevation of hippocampal TNF-α levels and memory deficits in mice.

21 January 2018

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Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.

21 January 2018

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Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

21 January 2018

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Neuroinflammation in Parkinson's disease: a target for neuroprotection?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Glia: initiators and progressors of pathology in Parkinson's disease

21 January 2018

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Alpha-synuclein stimulation of astrocytes: Potential role for neuroinflammation and neuroprotection

21 January 2018

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Progranulin is a mediator of the wound response

21 January 2018

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The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Inflammatory proteins in plasma and the risk of dementia: the rotterdam study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

TREM2 Variants in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Genome-wide association study of Alzheimer's disease with psychotic symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Toll-like receptor 9 promoter polymorphism is associated with decreased risk of Alzheimer's disease in Han Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Immune and behavioral consequences of microglial reactivity in the aged brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Metabolic syndrome, mild cognitive impairment and Alzheimer's disease--the emerging role of systemic low-grade inflammation and adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

The relationship between body mass index and incidental mild cognitive impairment, Alzheimer's disease and vascular dementia in elderly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Obesity is linked with lower brain volume in 700 AD and MCI patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Cognitive decline and oral health in middle-aged adults in the ARIC study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Periodontitis is associated with cognitive impairment among older adults: analysis of NHANES-III

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Long-term efficacy and safety of celecoxib in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Extended results of the Alzheimer's disease anti-inflammatory prevention trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Neuroinflammation in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Quantitive cytokine mRNA expression profiles in the colonic mucosa of patients with steroid naïve ulcerative colitis during active and quiescent disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Colonic inflammation in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Microglia activation mediates fibrillar amyloid-β toxicity in the aged primate cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

In vivo imaging of neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Imaging of microglia in patients with neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Increased binding of peripheral benzodiazepine receptor in mild cognitive impairment-dementia converters measured by positron emission tomography with [¹¹C]DAA1106.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

In vivo detection of microglial activation in frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Microglia in degenerative neurological disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Patterns of microglial cell activation in frontotemporal lobar degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Fully automated synthesis of PET TSPO radioligands [11C]DAA1106 and [18F]FEDAA1106.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Molecular imaging of microglia/macrophages in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Influence of TSPO genotype on 11C-PBR28 standardized uptake values

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-015-0531-7

Increased plasma TACE activity in subjects with mild cognitive impairment and patients with Alzheimer's disease

21 January 2018

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12 December 2020

[Abstracts of the 9th Conference on Alzheimer Disease, Kecskemet, Hungary, September 21-23, 2005]

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12 December 2020

Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches

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12 December 2020

Rheumatoid arthritis and Alzheimer's disease: genetic and epigenetic links in inflammatory regulation

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12 December 2020

Microglial response to amyloid plaques in APPsw transgenic mice.

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12 December 2020

FTDP-17: phenotypical heterogeneity within P301S

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12 December 2020

The triggering receptor expressed on myeloid cells 2: "TREM-ming" the inflammatory component associated with Alzheimer's disease

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12 December 2020

Inflammatory processes in Alzheimer's disease

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12 December 2020

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

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12 December 2020

Etiology and pathogenesis of Parkinson's disease

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12 December 2020

GM-CSF upregulated in rheumatoid arthritis reverses cognitive impairment and amyloidosis in Alzheimer mice.

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12 December 2020

Rivastigmine in dementia associated with Parkinson's disease and Alzheimer's disease: similarities and differences

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12 December 2020

Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial

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12 December 2020

10.1007/S11910-015-0531-7

Identifiers

DOI

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Dimensions Publication ID

2 September 2017

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