Aptamer-conjugated polymeric nanoparticles for targeted cancer therapy (Q38383216)

2 September 2017

title

Aptamer-conjugated polymeric nanoparticles for targeted cancer therapy (English)

1 reference

2 September 2017

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Athulya Aravind

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Yasuhiko Yoshida

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Toru Maekawa

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

1 December 2012

1 reference

Drug delivery and translational research

2 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

418-436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25787323%20AND%20SRC:MED&resulttype=core&format=json

Nanotechnology and aptamers: applications in drug delivery

6 June 2020

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A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA.

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21 January 2018

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Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys

21 January 2018

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Developing aptamers into therapeutics

21 January 2018

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Crystal structure of NF- B (p50)2 complexed to a high-affinity RNA aptamer

21 January 2018

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AGRO100 inhibits activation of nuclear factor-kappaB (NF-kappaB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin.

21 January 2018

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Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates

21 January 2018

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Aptamers against extracellular targets for in vivo applications

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Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells.

21 January 2018

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A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165

21 January 2018

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Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor

21 January 2018

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Pegaptanib for neovascular age-related macular degeneration

21 January 2018

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Pegaptanib: the first antiangiogenic agent approved for neovascular macular degeneration

21 January 2018

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In vitro selection of RNA molecules that bind specific ligands

21 January 2018

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Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

21 January 2018

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Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes.

21 January 2018

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Discovery and development of therapeutic aptamers.

21 January 2018

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Application of locked nucleic acids to improve aptamer in vivo stability and targeting function

21 January 2018

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Anti-HER2 immunoliposomes for targeted drug delivery

21 January 2018

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Selective targeting of immunoliposomal doxorubicin against human multiple myeloma in vitro and ex vivo

21 January 2018

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Controlled drug release from hydrogel nanoparticle networks

21 January 2018

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A polycaprolactone nanoparticle formulation of cyclosporin-A improves the prediction of area under the curve using a limited sampling strategy.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Biodegradable microspheres as controlled-release tetanus toxoid delivery systems.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Characterization of nanoparticle uptake by endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

In vitro characterization of polyorthoester microparticles containing bupivacaine

21 January 2018

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Biodegradation and biocompatibility of PLA and PLGA microspheres

21 January 2018

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Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Surface functionalization of PLGA nanoparticles by non-covalent insertion of a homo-bifunctional spacer for active targeting in cancer therapy.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Nanoparticles in cancer therapy and diagnosis

21 January 2018

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Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment

21 January 2018

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Exploiting the hallmarks of cancer: the future conquest of breast cancer

21 January 2018

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Molecular targets and cancer therapeutics: discovery, development and clinical validation

21 January 2018

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Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

21 January 2018

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Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes

21 January 2018

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Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis

21 January 2018

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Size of IgG-opsonized particles determines macrophage response during internalization

21 January 2018

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Endocytosis of nanomedicines.

21 January 2018

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Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

21 January 2018

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Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells

21 January 2018

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Polymers for the sustained release of proteins and other macromolecules

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Polysaccharide-decorated nanoparticles

21 January 2018

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Influence of polysaccharide coating on the interactions of nanoparticles with biological systems

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Cell-specific targeting of nanoparticles by multivalent attachment of small molecules

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies

21 January 2018

1 reference

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Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Biodegradable long-circulating polymeric nanospheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Aptamer conjugated magnetic nanoparticles as nanosurgeons.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Current advances in research and clinical applications of PLGA-based nanotechnology

21 January 2018

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A simple synthetic route to the formation of a block copolymer of poly(lactic-co-glycolic acid) and polylysine for the fabrication of functionalized, degradable structures for biomedical applications

21 January 2018

1 reference

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Microparticles of novel branched copolymers of lactic acid and amino acids: preparation and characterization

21 January 2018

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Ligand-specific targeting of microspheres to phagocytes by surface modification with poly(L-lysine)-grafted poly(ethylene glycol) conjugate

21 January 2018

1 reference

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Production of microspheres with surface amino groups from blends of Poly(Lactide-co-glycolide) and Poly(epsilon-CBZ-L-lysine) and use for encapsulation

21 January 2018

1 reference

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Surface modification of PLGA microspheres.

21 January 2018

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Integration of surface modification and 3D fabrication techniques to prepare patterned poly(L-lactide) substrates allowing regionally selective cell adhesion

21 January 2018

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Controllable surface modification of poly(lactic-co-glycolic acid) (PLGA) by hydrolysis or aminolysis I: physical, chemical, and theoretical aspects.

21 January 2018

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Plasma‐treated, collagen‐anchored polylactone: Its cell affinity evaluation under shear or shear‐free conditions

21 January 2018

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Characterization of surface property of poly(lactide-co-glycolide) after oxygen plasma treatment

21 January 2018

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Delivering cargoes into cancer cells using DNA aptamers targeting internalized surface portals

21 January 2018

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Phototoxic aptamers selectively enter and kill epithelial cancer cells

21 January 2018

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Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells

21 January 2018

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Aptamer:toxin conjugates that specifically target prostate tumor cells

21 January 2018

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Aptamer-based biosensor arrays for detection and quantification of biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Aptamer-targeted cell-specific RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Smart multifunctional nanostructure for targeted cancer chemotherapy and magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Liposome-anchored vascular endothelial growth factor aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Nanoparticle-aptamer conjugates for cancer cell targeting and detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Multifunctional plasmonic shell-magnetic core nanoparticles for targeted diagnostics, isolation, and photothermal destruction of tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Peptide- and aptamer-functionalized nanovectors for targeted delivery of therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Aptamer therapeutics advance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Microfluidic system for studying the interaction of nanoparticles and microparticles with cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imaging applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Combination of local, nonviral IL12 gene therapy and systemic paclitaxel treatment in a metastatic breast cancer model

21 January 2018

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Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug

21 January 2018

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siRNA inhibition of telomerase enhances the anti-cancer effect of doxorubicin in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Cisplatin incorporated in microspheres: development and fundamental studies for its clinical application

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Characterization of cisplatin cytotoxicity delivered from PLGA-systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Anticancer activity of cisplatin-loaded PLGA-mPEG nanoparticles on LNCaP prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

ChemoRad nanoparticles: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

DNA aptamers that bind to MUC1 tumour marker: design and characterization of MUC1-binding single-stranded DNA aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Novel aptamer-nanoparticle bioconjugates enhances delivery of anticancer drug to MUC1-positive cancer cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Angiogenesis in cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

In vitro selection of the RNA aptamer against the Sialyl Lewis X and its inhibition of the cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Aptamers evolved from live cells as effective molecular probes for cancer study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Cell-specific internalization study of an aptamer from whole cell selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Tenascin-C aptamers are generated using tumor cells and purified protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels. selective targeting of endothelial regulatory protein pigpen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Inhibitory DNA ligands to platelet-derived growth factor B-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Detection of oncoprotein platelet-derived growth factor using a fluorescent signaling complex of an aptamer and TOTO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Layer-by-Layer Surface Modification and Patterned Electrostatic Deposition of Quantum Dots

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Emerging Technologies of Polymeric Nanoparticles in Cancer Drug Delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-012-0104-0

Production and surface modification of polylactide-based polymeric scaffolds for soft-tissue engineering.

21 January 2018

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12 December 2020

Aptamer-labeled PLGA nanoparticles for targeting cancer cells.

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12 December 2020

Nucleic Acid Selection and the Challenge of Combinatorial Chemistry

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12 December 2020

Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma

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12 December 2020

Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor.

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12 December 2020

Early intervention in cancer using monoclonal antibodies and other biological ligands: micropharmacology and the "binding site barrier"

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12 December 2020

Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen

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12 December 2020

Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors

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Toward third-generation aptamers: Spiegelmers and their therapeutic prospects

1 reference

12 December 2020

Current evaluation of the tissue localization and diagnostic utility of prostate specific membrane antigen

1 reference

12 December 2020

A method for the high efficiency of water-soluble carbodiimide-mediated amidation

1 reference

12 December 2020

In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma.

1 reference

12 December 2020

In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase

1 reference

12 December 2020

Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: a novel mechanism of tumor angiogenesis

1 reference

12 December 2020

PLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties

1 reference

12 December 2020

Polylactide-poly(ethylene glycol) micellar-like particles as potential drug carriers: production, colloidal properties and biological performance

1 reference

12 December 2020

Tissue reaction of bioabsorbable ultra high strength poly (L-lactide) rod. A long-term study in rabbits

1 reference

12 December 2020

‘Stealth’ corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption

1 reference

12 December 2020

Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery

1 reference

12 December 2020

Poly(ethylene glycol)-coated nanospheres: potential carriers for intravenous drug administration

1 reference

12 December 2020

Nanotechnology-Based Cancer Therapeutics—Promise and Challenge—Lessons Learned Through the NCI Alliance for Nanotechnology in Cancer

1 reference

12 December 2020

(6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin

1 reference

12 December 2020

Transport of molecules in the tumor interstitium: a review

1 reference

12 December 2020

Long-term stability of PBCA nanoparticle suspensions

1 reference

12 December 2020

Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA-mPEG nanoparticles

1 reference

12 December 2020

Spiegelmers: Biostable Aptamers

1 reference

12 December 2020

An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform

1 reference

12 December 2020

Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions

1 reference

12 December 2020

Surface modification of polyanhydride microspheres

1 reference

12 December 2020

Determinants of tumor blood flow: a review

1 reference

12 December 2020

Label-free protein biosensor based on aptamer-modified carbon nanotube field-effect transistors

1 reference

12 December 2020

Technology evaluation: pegaptanib, Eyetech/Pfizer.

1 reference

12 December 2020

Tumor targeting by an aptamer

1 reference

12 December 2020

Tissue perfusion inhomogeneity during early tumor growth in rats

1 reference

12 December 2020

Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity

1 reference

12 December 2020

Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide-aptamer (NX1838) in rhesus monkeys

1 reference

12 December 2020

Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size

1 reference

12 December 2020

Aptamers as therapeutic and diagnostic reagents: problems and prospects

1 reference

12 December 2020