Pooled Analysis of CNS Response to Alectinib in Two Studies of Pretreated Patients With ALK-Positive Non-Small-Cell Lung Cancer (Q38384492)

2 September 2017

title

Pooled Analysis of CNS Response to Alectinib in Two Studies of Pretreated Patients With ALK-Positive Non-Small-Cell Lung Cancer (English)

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2 September 2017

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5 June 2020

James Chih-Hsin Yang

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5 June 2020

author name string

Shirish M Gadgeel

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Alice T Shaw

2

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Ramaswamy Govindan

3

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Leena Gandhi

4

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Mark A Socinski

5

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D Ross Camidge

6

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Luigi De Petris

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Dong-Wan Kim

8

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5 June 2020

Alberto Chiappori

9

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5 June 2020

Michael Duruisseaux

11

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Lucio Crino

12

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Tommaso De Pas

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Eric Dansin

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5 June 2020

Antje Tessmer

15

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5 June 2020

Ji-Youn Han

17

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5 June 2020

Walter Bordogna

18

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Sophie Golding

19

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Ali Zeaiter

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Sai-Hong Ignatius Ou

21

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language of work or name

English

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publication date

31 October 2016

1 reference

Journal of Clinical Oncology

2 September 2017

published in

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5 June 2020

volume

34

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5 June 2020

issue

34

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5 June 2020

page(s)

4079-4085

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Irradiation of brain metastases from lung cancer: a retrospective study

5 June 2020

cites work

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12 December 2020

Drug delivery to the central nervous system: a review

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12 December 2020

CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib.

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12 December 2020

Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study

1 reference

12 December 2020

CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): a single-arm, open-label, phase 1-2 study

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12 December 2020

Characteristics of long-term survivors of brain metastases from lung cancer

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12 December 2020

Clinical benefit of continuing ALK inhibition with crizotinib beyond initial disease progression in patients with advanced ALK-positive NSCLC.

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12 December 2020

Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study.

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12 December 2020

Clinical characteristics of brain metastases from lung cancer according to histological type: Pretreatment evaluation and survival following whole-brain radiotherapy

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12 December 2020

Molecular pathways: resistance to kinase inhibitors and implications for therapeutic strategies

1 reference

12 December 2020

Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study.

1 reference

12 December 2020

Antitumor activity of the selective ALK inhibitor alectinib in models of intracranial metastases

1 reference

12 December 2020

Alectinib: a review of its use in advanced ALK-rearranged non-small cell lung cancer

1 reference

12 December 2020

First-line crizotinib versus chemotherapy in ALK-positive lung cancer

1 reference

12 December 2020

Alectinib salvages CNS relapses in ALK-positive lung cancer patients previously treated with crizotinib and ceritinib

1 reference

12 December 2020

Alectinib induces a durable (>15 months) complete response in an ALK-positive non-small cell lung cancer patient who progressed on crizotinib with diffuse leptomeningeal carcinomatosis

1 reference

12 December 2020

Clinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastases

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12 December 2020

FDA approval: ceritinib for the treatment of metastatic anaplastic lymphoma kinase-positive non-small cell lung cancer.

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12 December 2020

Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2).

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12 December 2020

Alectinib in Crizotinib-Refractory ALK-Rearranged Non-Small-Cell Lung Cancer: A Phase II Global Study.

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12 December 2020

Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial

1 reference

12 December 2020