Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays. (Q38407621)

2 September 2017

Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays (English)

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13 May 2020

1

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13 May 2020

Robert E Boer

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13 May 2020

John S Schneekloth

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13 May 2020

author name string

Michelle H Moon

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13 May 2020

Peter Gareiss

4

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13 May 2020

publication date

13 December 2016

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2 September 2017

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13 May 2020

volume

12

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issue

2

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13 May 2020

page(s)

435-443

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describes a project that uses

13 May 2020

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

Relationship between internucleotide linkage geometry and the stability of RNA.

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12 December 2020

miR-21-mediated tumor growth

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12 December 2020

A pipeline for ligand discovery using small-molecule microarrays

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12 December 2020

A method for the covalent capture and screening of diverse small molecules in a microarray format

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12 December 2020

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

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12 December 2020

A small molecule microarray platform to select RNA internal loop-ligand interactions

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12 December 2020

Targeting RNA with small molecules

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12 December 2020

MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators

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12 December 2020

Small-molecule inhibitors of microrna miR-21 function

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12 December 2020

Discovering ligands for a microRNA precursor with peptoid microarrays

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12 December 2020

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

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12 December 2020

The art of the chemical probe

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12 December 2020

MicroRNA-21: from cancer to cardiovascular disease

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12 December 2020

Discovery of a proneurogenic, neuroprotective chemical

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12 December 2020

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.

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12 December 2020

Development of proneurogenic, neuroprotective small molecules

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12 December 2020

Small molecule microarrays: the first decade and beyond.

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12 December 2020

MicroRNA-21: a ubiquitously expressed pro-survival factor in cancer and other diseases

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12 December 2020

The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR-21 function by directly targeting its precursor.

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12 December 2020

Recent advances in developing small molecules targeting RNA.

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12 December 2020

Long noncoding RNAs and the genetics of cancer.

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12 December 2020

Diversifying microRNA sequence and function

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12 December 2020

Association of a peptoid ligand with the apical loop of pri-miR-21 inhibits cleavage by Drosha

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12 December 2020

Recent discoveries and applications involving small-molecule microarrays

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12 December 2020

Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties

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12 December 2020

Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays

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12 December 2020

MicroRNAs in cancer: biomarkers, functions and therapy

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12 December 2020

P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage

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12 December 2020

The expanding view of RNA and DNA function

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12 December 2020

High-throughput platform assay technology for the discovery of pre-microrna-selective small molecule probes.

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12 December 2020

Targeting the HIV RNA genome: high-hanging fruit only needs a longer ladder

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12 December 2020

Anti-miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network Deregulation.

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12 December 2020

Aryl amide small-molecule inhibitors of microRNA miR-21 function.

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12 December 2020

Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression

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12 December 2020

Long noncoding RNAs in cancer: from function to translation

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12 December 2020

Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins

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12 December 2020

The Emerging Role of RNA as a Therapeutic Target for Small Molecules.

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12 December 2020

10.1021/ACSCHEMBIO.6B00945

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6341489&resulttype=core&format=json

13 May 2020

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13 May 2020

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