A randomized phase I study of the safety and immunogenicity of three ascending dose levels of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults. (Q38415816)

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scientific article published on 21 February 2015

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English	A randomized phase I study of the safety and immunogenicity of three ascending dose levels of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults.	scientific article published on 21 February 2015

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1 March 2020

A randomized phase I study of the safety and immunogenicity of three ascending dose levels of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults (English)

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Staphylococcus aureus

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William C. Gruber

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William Gruber

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Kathrin U Jansen

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David Cooper

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Edward T Zito

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Annaliesa S Anderson

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Annaliesa S Anderson

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Sepehr Shakib

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Denise Rill

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James Baber

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Douglas Girgenti

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Douglas Girgenti

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Michael Nissen

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Qin Jiang

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Joseph Eiden

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Emilio A Emini

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21 February 2015

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1846-1854

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1 March 2020

Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance

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Update on infective endocarditis

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Increase in community-acquired methicillin-resistant Staphylococcus aureus in children

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Invasive methicillin-resistant Staphylococcus aureus infections in the United States

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National trends in Staphylococcus aureus infection rates: impact on economic burden and mortality over a 6-year period (1998-2003).

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Laboratory-based surveillance of current antimicrobial resistance patterns and trends among Staphylococcus aureus: 2005 status in the United States

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Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections

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NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007

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Population-based incidence and characteristics of community-onset Staphylococcus aureus infections with bacteremia in 4 metropolitan Connecticut areas, 1998.

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Use of a Staphylococcus aureus conjugate vaccine in patients receiving hemodialysis.

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Prospects for active and passive immunization against Staphylococcus aureus

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Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery: a randomized trial

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Vaccine review: "Staphyloccocus aureus vaccines: problems and prospects".

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Naturally occurring IgG antibody levels to the Staphylococcus aureus protein IsdB in humans

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Staphylococcus aureus manganese transport protein C is a highly conserved cell surface protein that elicits protective immunity against S. aureus and Staphylococcus epidermidis

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7 January 2021

Staphylococcus aureus capsular polysaccharides

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Challenges for the evaluation of Staphylococcus aureus protein based vaccines: monitoring antigenic diversity

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Heterogeneous in vivo expression of clumping factor A and capsular polysaccharide by Staphylococcus aureus: implications for vaccine design.

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Immunofluorescence microscopy for the detection of surface antigens in methicillin-resistant Staphylococcus aureus (MRSA).

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Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors ClfA and ClfB, the serine-aspartate repeat protein SdrE and protein A.

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Regulation of Staphylococcus aureus MntC expression and its role in response to oxidative stress

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A recombinant clumping factor A-containing vaccine induces functional antibodies to Staphylococcus aureus that are not observed after natural exposure

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Capsular polysaccharides are an important immune evasion mechanism for Staphylococcus aureus

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Age-related decline in immunity: implications for vaccine responsiveness

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Evaluation of approaches to monitor Staphylococcus aureus virulence factor expression during human disease.

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Progress toward a Staphylococcus aureus vaccine

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Protective immunity against recurrent Staphylococcus aureus skin infection requires antibody and interleukin-17A.

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Infections associated with chronic granulomatous disease: linking genetics to phenotypic expression

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Identification of in vivo-expressed antigens of Staphylococcus aureus and their use in vaccinations for protection against nasal carriage

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Comparison of antibody repertoires against Staphylococcus aureus in healthy individuals and in acutely infected patients

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Natural antibodies in normal human serum inhibit Staphylococcus aureus capsular polysaccharide vaccine efficacy

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Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia

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Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non-carriers

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Characterization of novel LPXTG-containing proteins of Staphylococcus aureus identified from genome sequences

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