Structural biological study of self-resistance determinants in antibiotic-producing actinomycetes (Q38420859)

2 September 2017

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title

Structural biological study of self-resistance determinants in antibiotic-producing actinomycetes (English)

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2 September 2017

Masanori Sugiyama

1

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2 September 2017

publication date

15 April 2015

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The Journal of Antibiotics

2 September 2017

published in

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2 September 2017

volume

68

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2 September 2017

issue

9

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2 September 2017

page(s)

543-550

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2 September 2017

cites work

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Transposition of R factor genes to bacteriophage lambda

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Completion of the nucleotide sequence of the central region of Tn5 confirms the presence of three resistance genes

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Crystallization and preliminary X-ray diffraction studies of bleomycin-binding protein encoded on the transposon Tn5.

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Characterization of the bleomycin resistance determinant encoded on the transposon Tn5.

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Catalytic Mechanism of Bleomycin N-Acetyltransferase Proposed on the Basis of Its Crystal Structure

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DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus.

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Overexpression of the thiostrepton-resistance gene from Streptomyces azureus in Escherichia coli and characterization of recognition sites of the 23S rRNA A1067 2'-methyltransferase in the guanosine triphosphatase center of 23S ribosomal RNA.

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Secondary aminoglycoside resistance in aminoglycoside-producing strains of Streptomyces

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21 January 2018

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Inhibition of cell wall biosynthesis by analogues and alanine

21 January 2018

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A Side Reaction of Alanine Racemase: Transamination of Cycloserine,

21 January 2018

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Crystallographic study of steps along the reaction pathway of D-amino acid aminotransferase

21 January 2018

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Suicide substrates for the alanine racemase of Escherichia coli B

21 January 2018

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Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

21 January 2018

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Self-protection mechanism in D-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization, and kinetics of its alanine racemase and D-alanyl-D-alanine ligase, which are target enzymes of D-cycloserine

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Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product

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Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae

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The transposon Tn5 carries a bleomycin-resistance determinant

21 January 2018

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Characterization of a quinone reductase activity for the mitomycin C binding protein (MRD): Functional switching from a drug-activating enzyme to a drug-binding protein

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12 December 2020

[Self-protection mechanisms of antibiotic-producing microorganisms]

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12 December 2020

Mechanism of d -Cycloserine Action: Alanine Racemase from Escherichia coli W

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12 December 2020

Molecular cloning of a D-cycloserine resistance gene from D-cycloserine-producing Streptomyces garyphalus.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Chemistry and mechanism of action of bleomycin

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12 December 2020

The enzymatic synthesis of D-alanyl-D-alanine. I. Purification and properties of D-alanyl-D-alanine synthetase

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12 December 2020

Effects of Ethidium Bromide on Growth and on Loss of the Penicillinase Plasmid of Staphylococcus aureus

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12 December 2020

New antibiotics, bleomycin A and B

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12 December 2020

Site of action of a ribosomal RNA methylase conferring resistance to thiostrepton

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12 December 2020

Molecular cloning and expression in Escherichia coli of bleomycin-resistance gene from a methicillin-resistant Staphylococcus aureus and its association with IS431 mec.

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12 December 2020

Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein

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12 December 2020

IS431mec-mediated integration of a bleomycin-resistance gene into the chromosome of a methicillin-resistant Staphylococcus aureus strain isolated in Japan

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12 December 2020

Inactivation of bleomycin by anN-acetyltransferase in the bleomycin-producing strainStreptomyces verticillus

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12 December 2020

Susceptibility of protein synthesis to streptomycin in streptomycin-producingStreptomyces griseus

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12 December 2020

Individualized therapy versus standard regimens in the treatment of Mycobacterium avium infections

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12 December 2020

Enzymes in the D-alanine branch of bacterial cell wall peptidoglycan assembly

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12 December 2020

Identifiers

DOI

10.1038/JA.2015.32

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Dimensions Publication ID

2 September 2017

1001674309

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