Metabolic and nutritional support of critically ill patients: consensus and controversies. (Q38426589)

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5 March 2020

review article

2 references

28 October 2022

Metabolic and nutritional support of critically ill patients: consensus and controversies (English)

1 reference

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23 July 2019

Arthur R H van Zanten

2

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Gianni Biolo

4

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Michael P Casaer

5

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Greet Van den Berghe

14

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Jean-Louis Vincent

17

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author name string

Jean-Charles Preiser

1

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Mette M Berger

3

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Gordon S Doig

6

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Richard D Griffiths

7

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Daren K Heyland

8

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Michael Hiesmayr

9

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Gaetano Iapichino

10

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Alessandro Laviano

11

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Claude Pichard

12

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Pierre Singer

13

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Jan Wernerman

15

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Paul Wischmeyer

16

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publication date

29 January 2015

4 references

25 June 2019

23 July 2019

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5 March 2020

28 October 2022

4 references

25 June 2019

23 July 2019

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5 March 2020

28 October 2022

19

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5 March 2020

page(s)

35

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Creative Commons Attribution

5 March 2020

copyright license

3 references

25 June 2019

23 July 2019

28 October 2022

0 references

Modulation of Dietary Lipid Composition During Acute Respiratory Distress Syndrome: Systematic Review and Meta-Analysis

1 reference

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High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial

6 September 2017

1 reference

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Metabolic response to the stress of critical illness

6 September 2017

1 reference

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Parenteral glutamine supplementation in critical illness: a systematic review

6 September 2017

1 reference

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Calorie intake and patient outcomes in severe acute kidney injury: findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial

6 September 2017

1 reference

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Enteral omega-3 fatty acid supplementation in adult patients with acute respiratory distress syndrome: a systematic review of randomized controlled trials with meta-analysis and trial sequential analysis

6 September 2017

1 reference

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Whole body protein turnover in critically ill patients with multiple organ failure

6 September 2017

1 reference

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Metabolomic derangements are associated with mortality in critically ill adult patients

6 September 2017

1 reference

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Nutritional-risk scoring systems in the intensive care unit

6 September 2017

1 reference

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The effect of glutamine therapy on outcomes in critically ill patients: a meta-analysis of randomized controlled trials

6 September 2017

1 reference

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Energy estimation and measurement in critically ill patients

6 September 2017

1 reference

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Update on antioxidant micronutrients in the critically ill.

6 September 2017

1 reference

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Bedside ultrasound is a practical and reliable measurement tool for assessing quadriceps muscle layer thickness

6 September 2017

1 reference

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Whole body protein kinetics during hypocaloric and normocaloric feeding in critically ill patients

6 September 2017

1 reference

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Use of gastric residual volume to guide enteral nutrition in critically ill patients: a brief systematic review of clinical studies

6 September 2017

1 reference

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Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a randomized controlled trial

6 September 2017

1 reference

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Parenteral fish oil lipid emulsions in the critically ill: a systematic review and meta-analysis

6 September 2017

1 reference

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Impact of the administration of probiotics on mortality in critically ill adult patients: a meta-analysis of randomized controlled trials

6 September 2017

1 reference

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Reconciling divergent results of the latest parenteral nutrition studies in the ICU.

6 September 2017

1 reference

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Does artificial nutrition improve outcome of critical illness?

6 September 2017

1 reference

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Effect of not monitoring residual gastric volume on risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a randomized controlled trial

6 September 2017

1 reference

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A systematic literature review and meta-analysis of randomized clinical trials of parenteral glutamine supplementation

6 September 2017

1 reference

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The role of ω-3 fatty acid supplemented parenteral nutrition in critical illness in adults: a systematic review and meta-analysis.

6 September 2017

1 reference

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The stress response and critical illness: a review

6 September 2017

1 reference

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Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

6 September 2017

1 reference

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Appropriate protein provision in critical illness: a systematic and narrative review

6 September 2017

1 reference

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Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis

6 September 2017

1 reference

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Antioxidant micronutrients in the critically ill: a systematic review and meta-analysis

6 September 2017

1 reference

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A double-blind, randomized clinical trial comparing soybean oil-based versus olive oil-based lipid emulsions in adult medical-surgical intensive care unit patients requiring parenteral nutrition

6 September 2017

1 reference

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Selenium and human health.

6 September 2017

1 reference

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Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial

6 September 2017

1 reference

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Glutamine and glutathione at ICU admission in relation to outcome

6 September 2017

1 reference

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Micronutrient supplementation for critically ill adults: a systematic review and meta-analysis

6 September 2017

1 reference

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Perioperative use of arginine-supplemented diets: a systematic review of the evidence

6 September 2017

1 reference

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Randomized trial of initial trophic versus full-energy enteral nutrition in mechanically ventilated patients with acute respiratory failure

6 September 2017

1 reference

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Intensive insulin therapy in severely burned pediatric patients: a prospective randomized trial

6 September 2017

1 reference

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An overview of evidence from systematic reviews evaluating early enteral nutrition in critically ill patients: more convincing evidence is needed.

6 September 2017

1 reference

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Early enteral nutrition, provided within 24 h of injury or intensive care unit admission, significantly reduces mortality in critically ill patients: a meta-analysis of randomised controlled trials

6 September 2017

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Effects of inflammation and/or inactivity on the need for dietary protein.

6 September 2017

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Parenteral nutrition in the critically ill patient

6 September 2017

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Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition: Executive Summary

6 September 2017

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Gastric residual volume and aspiration in critically ill patients receiving gastric feedings

6 September 2017

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The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data

6 September 2017

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Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients

6 September 2017

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Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial

6 September 2017

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Reduction of nosocomial pneumonia after major burns by trace element supplementation: aggregation of two randomised trials

6 September 2017

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Omega-3 fatty acids improve the diagnosis-related clinical outcome

6 September 2017

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Intensive insulin therapy protects the endothelium of critically ill patients

6 September 2017

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Acute hyperglycemia and the innate immune system: clinical, cellular, and molecular aspects

6 September 2017

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The pathobiology of diabetic complications: a unifying mechanism

6 September 2017

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Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient

6 September 2017

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The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals

6 September 2017

1 reference

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Antioxidant therapy in intensive care

6 September 2017

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Influence of the critically ill state on host-pathogen interactions within the intestine: gut-derived sepsis redefined

6 September 2017

1 reference

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Cysteine supplementation improves the erythrocyte glutathione synthesis rate in children with severe edematous malnutrition

6 September 2017

1 reference

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Intensive insulin therapy in critically ill patients

6 September 2017

1 reference

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Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues

6 September 2017

1 reference

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Refeeding hypophosphatemia in critically ill patients in an intensive care unit. A prospective study

6 September 2017

1 reference

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Ventilatory response to high caloric loads in critically ill patients.

6 September 2017

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Perioperative total parenteral nutrition in surgical patients

27 September 2017

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A randomized trial of glutamine and antioxidants in critically ill patients

27 September 2017

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Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients

23 June 2018

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Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: A prospective, controlled, randomized clinical trial*

23 June 2018

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Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma

23 June 2018

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Overfeeding macronutrients to critically ill adults: metabolic complications

23 June 2018

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Implementing the PEP uP Protocol in Critical Care Units in Canada: Results of a Multicenter, Quality Improvement Study.

23 June 2018

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Evaluation of three indirect calorimetry devices in mechanically ventilated patients: which device compares best with the Deltatrac II(®)? A prospective observational study

31 August 2018

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Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial.

31 August 2018

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Metabolic profiling of serum samples by 1H nuclear magnetic resonance spectroscopy as a potential diagnostic approach for septic shock.

31 August 2018

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Acute skeletal muscle wasting in critical illness.

31 August 2018

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Enhanced protein-energy provision via the enteral route feeding protocol in critically ill patients: results of a cluster randomized trial

31 August 2018

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Glutamine and antioxidants in critically ill patients

31 August 2018

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Impact of early parenteral nutrition on muscle and adipose tissue compartments during critical illness.

31 August 2018

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Avoiding underfeeding in severely ill patients

31 August 2018

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Insufficient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness.

31 August 2018

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Indirect calorimetry in mechanically ventilated patients. A systematic comparison of three instruments

31 August 2018

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Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Scandinavian glutamine trial: a pragmatic multi-centre randomised clinical trial of intensive care unit patients

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Randomised trial of glutamine, selenium, or both, to supplement parenteral nutrition for critically ill patients

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Early enteral nutrition and outcomes of critically ill patients treated with vasopressors and mechanical ventilation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

The relationship between nutritional intake and clinical outcomes in critically ill patients: results of an international multicenter observational study.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

The effect of strict blood glucose control on biliary sludge and cholestasis in critically ill patients

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Evaluation of the effect of prospective patient diaries on emotional well-being in intensive care unit survivors: a randomized controlled trial.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

High-dose insulin therapy attenuates systemic inflammatory response in coronary artery bypass grafting patients

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Nitrogen balance, protein loss, and the open abdomen.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Frequency of under- and overfeeding in mechanically ventilated ICU patients: causes and possible consequences

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Computerized energy balance and complications in critically ill patients: an observational study

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Clinical outcome of immunonutrition in a heterogeneous intensive care population

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Extremity hyperinsulinemia stimulates muscle protein synthesis in severely injured patients

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Early enteral immunonutrition in patients with severe sepsis: results of an interim analysis of a randomized multicentre clinical trial

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

A randomized controlled trial of preoperative oral supplementation with a specialized diet in patients with gastrointestinal cancer

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Fatty infiltration of the liver in severely burned pediatric patients: autopsy findings and clinical implications

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Plasma glutamine depletion and patient outcome in acute ICU admissions

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Are patients fed appropriately according to their caloric requirements?

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310041

Early versus Late Parenteral Nutrition in Critically Ill Adults

31 August 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13054-015-0737-8

Intensive Insulin Therapy Exerts Antiinflammatory Effects in Critically Ill Patients and Counteracts the Adverse Effect of Low Mannose-Binding Lectin Levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13054-015-0737-8

Survival Benefits of Intensive Insulin Therapy in Critical Illness: Impact of Maintaining Normoglycemia Versus Glycemia-Independent Actions of Insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13054-015-0737-8

Procalcitonin for reduced antibiotic exposure in the critical care setting: a systematic review and an economic evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13054-015-0737-8

ESPEN Guidelines on Parenteral Nutrition: Intensive care

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13054-015-0737-8

Role of Disease and Macronutrient Dose in the Randomized Controlled EPaNIC Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13054-015-0737-8

The relationship between labour cost per patient and the size of intensive care units: a multicentre prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13054-015-0737-8

Temporal trend of short-term mortality in severely ill patients receiving parenteral glutamine supplementation

21 January 2018

1 reference

12 December 2020

Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle

1 reference

12 December 2020

REDOXs: important answers, many more questions raised!

1 reference

12 December 2020

Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial

1 reference

12 December 2020

When should we add parenteral to enteral nutrition?

1 reference

12 December 2020

Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans

1 reference

12 December 2020

An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein

1 reference

12 December 2020

Optimal protein requirements during the first 2 weeks after the onset of critical illness

1 reference

12 December 2020

Selenium, systemic immune response syndrome, sepsis, and outcome in critically ill patients

1 reference

12 December 2020

The metabolic consequences of critical illness: acute effects on glutamine and protein metabolism

1 reference

12 December 2020

Inactivity amplifies the catabolic response of skeletal muscle to cortisol

1 reference

12 December 2020

Impact of a computerized information system on quality of nutritional support in the ICU

1 reference

12 December 2020

Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock

1 reference

12 December 2020

Trace element supplementation after major burns modulates antioxidant status and clinical course by way of increased tissue trace element concentrations

1 reference

12 December 2020

Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial

1 reference

12 December 2020

Calorie restriction accelerates the catabolism of lean body mass during 2 wk of bed rest

1 reference

12 December 2020

Permissive underfeeding and intensive insulin therapy in critically ill patients: a randomized controlled trial

1 reference

12 December 2020

The tight calorie control study (TICACOS): a prospective, randomized, controlled pilot study of nutritional support in critically ill patients

1 reference

12 December 2020

Optimal amount of calories for critically ill patients: depends on how you slice the cake!

1 reference

12 December 2020

Optimal protein and energy nutrition decreases mortality in mechanically ventilated, critically ill patients: a prospective observational cohort study

1 reference

12 December 2020

Nutrition for critically ill patients: how much is enough?

1 reference

12 December 2020

Intensive care diaries and relatives' symptoms of posttraumatic stress disorder after critical illness: a pilot study

1 reference

12 December 2020

Provision of protein and energy in relation to measured requirements in intensive care patients

1 reference

12 December 2020

Evaluation of over- and underfeeding following the introduction of a protocol for weaning from parenteral to enteral nutrition in the intensive care unit

1 reference

12 December 2020

10.1186/S13054-015-0737-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25886997%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25886997%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

25886997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25886997%20AND%20SRC:MED&resulttype=core&format=json