Predicting the Uncertain Future of Aptamer-Based Diagnostics and Therapeutics. (Q38443249)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25913927%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

review article

3 references

8 September 2020

14 October 2020

Predicting the Uncertain Future of Aptamer-Based Diagnostics and Therapeutics (English)

1 reference

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6 March 2020

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8 September 2020

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14 October 2020

John G Bruno

1

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language of work or name

English

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publication date

16 April 2015

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6 March 2020

8 September 2020

14 October 2020

3 references

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6 March 2020

8 September 2020

14 October 2020

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issue

4

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6 March 2020

page(s)

6866-6887

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Creative Commons Attribution

6 March 2020

copyright license

2 references

8 September 2020

14 October 2020

0 references

Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscan™) platform.

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Current approaches in SELEX: An update to aptamer selection technology.

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Nucleic Acid aptamers: new methods for selection, stabilization, and application in biomedical science

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Efficient HIV-1 inhibition by a 16 nt-long RNA aptamer designed by combining in vitro selection and in silico optimisation strategies.

21 January 2018

1 reference

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Simultaneous improvement of specificity and affinity of aptamers against Streptococcus mutans by in silico maturation for biosensor development.

21 January 2018

1 reference

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In silico maturation of binding-specificity of DNA aptamers against Proteus mirabilis

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1 reference

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Competitive FRET-aptamer-based detection of methylphosphonic acid, a common nerve agent metabolite

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1 reference

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DNA aptamers developed against a soman derivative cross-react with the methylphosphonic acid core but not with flanking hydrophobic groups

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1 reference

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Development of aptamer beacons for rapid presumptive detection of Bacillus spores

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An aptamer beacon responsive to botulinum toxins

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Aptamer-based technology for food analysis

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Plastic-adherent DNA aptamer-magnetic bead and quantum dot sandwich assay for Campylobacter detection

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Selection and characterization of DNA aptamers with binding selectivity to Campylobacter jejuni using whole-cell SELEX.

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A novel screening method for competitive FRET-aptamers applied to E. coli assay development

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Evanescent wave DNA-aptamer biosensor based on long period gratings for the specific recognition of E. coli outer membrane proteins

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Application of DNA Aptamers and Quantum Dots to Lateral Flow Test Strips for Detection of Foodborne Pathogens with Improved Sensitivity versus Colloidal Gold

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Development of ssDNA aptamers for the sensitive detection of Salmonella typhimurium and Salmonella enteritidis

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Identification of Salmonella Typhimurium-specific DNA aptamers developed using whole-cell SELEX and FACS analysis

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Selection of DNA aptamers for capture and detection of Salmonella Typhimurium using a whole-cell SELEX approach in conjunction with cell sorting

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Selection and characterization of aptamers against Salmonella typhimurium using whole-bacterium Systemic Evolution of Ligands by Exponential Enrichment (SELEX).

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1 reference

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Selection, characterization, and application of DNA aptamers for the capture and detection of Salmonella enterica serovars

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Selection, characterization and application of nucleic acid aptamers for the capture and detection of human norovirus strains

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Selection of a DNA aptamer against norovirus capsid protein VP1.

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Ultrasensitive norovirus detection using DNA aptasensor technology

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A single-stranded DNA aptamer that selectively binds to Staphylococcus aureus enterotoxin B.

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DNA-aptamers binding aminoglycoside antibiotics

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Development of a single aptamer-based surface enhanced Raman scattering method for rapid detection of multiple pesticides

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1 reference

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Selection of DNA aptamers that bind to four organophosphorus pesticides

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1 reference

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Identification of environmental reservoirs of nontyphoidal salmonellosis: aptamer-assisted bioconcentration and subsequent detection of salmonella typhimurium by quantitative polymerase chain reaction

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Bio-capture of S. Typhimurium from surface water by aptamer for culture-free quantification.

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Nucleic acid aptamers for capture and detection of Listeria spp.

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Therapeutic RNA aptamers in clinical trials

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Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy

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Improving antisense oligonucleotide binding to human serum albumin: dramatic effect of ibuprofen conjugation

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Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood

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Aptamers as therapeutics.

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Pharmacokinetics and biodistribution of novel aptamer compositions

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High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication

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Selection of DNA aptamers that bind to influenza A viruses with high affinity and broad subtype specificity.

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Designing anti-influenza aptamers: novel quantitative structure activity relationship approach gives insights into aptamer-virus interaction

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Aptamers that bind to the hemagglutinin of the recent pandemic influenza virus H1N1 and efficiently inhibit agglutination

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1 reference

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Development, screening, and analysis of DNA aptamer libraries potentially useful for diagnosis and passive immunity of arboviruses

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A multifunctional bispecific antibody protects against Pseudomonas aeruginosa

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Anti-bacterial monoclonal antibodies: back to the future?

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Monoclonal antibody-based therapies for microbial diseases

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Development of bacteriostatic DNA aptamers for salmonella

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1 reference

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In vitro antibacterial effects of antilipopolysaccharide DNA aptamer-C1qrs complexes

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1 reference

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Aptamer–biotin–streptavidin–C1q complexes can trigger the classical complement pathway to kill cancer cells

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1 reference

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Commandeering a biological pathway using aptamer-derived molecular adaptors

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1 reference

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Preliminary development of DNA aptamer-Fc conjugate opsonins

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1 reference

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Neutralization of staphylococcal enterotoxin B by an aptamer antagonist

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1 reference

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DNA aptamers as a novel approach to neutralize Staphylococcus aureus α-toxin

21 January 2018

1 reference

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Recognition of Bungarus multicinctus venom by a DNA aptamer against β-bungarotoxin

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1 reference

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Rapid one-step selection method for generating nucleic acid aptamers: development of a DNA aptamer against α-bungarotoxin

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1 reference

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In vitro selection of DNA to chloroaromatics using magnetic microbead-based affinity separation and fluorescence detection

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Microfluidic approaches to rapid and efficient aptamer selection

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Influenza A virus-specific aptamers screened by using an integrated microfluidic system.

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Improving aptamer selection efficiency through volume dilution, magnetic concentration, and continuous washing in microfluidic channels

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Probing the limits of aptamer affinity with a microfluidic SELEX platform

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1 reference

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One-staged aptamer-based isolation and application of endothelial progenitor cells in a porcine myocardial infarction model.

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Immobilization of DNA aptamers via plasma polymerized allylamine film to construct an endothelial progenitor cell-capture surface

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Immobilized DNA aptamers used as potent attractors for porcine endothelial precursor cells

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A new technique for the isolation and surface immobilization of mesenchymal stem cells from whole bone marrow using high-specific DNA aptamers

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Aptamer antagonists of myelin-derived inhibitors promote axon growth

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Directing stem cell differentiation with antibodies.

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Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells

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Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections

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Novel therapeutic approaches for haemophilia

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Modifying cellular properties using artificial aptamer-lipid receptors

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In vitro selection of DNA aptamers to anthrax spores with electrochemiluminescence detection

21 January 2018

1 reference

12 December 2020

Comparative safety profiles of intravitreal bevacizumab, ranibizumab and pegaptanib: the analysis of the WHO database of adverse drug reactions

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Where are all the aptamers?

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A direct competitive assay-based aptasensor for sensitive determination of tetracycline residue in honey

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FDA announces plans to regulate LDTs

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First report of in vitro selection of RNA aptamers targeted to recombinant Loxosceles laeta spider toxins

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Aptamer-conjugated magnetic nanoparticles for extraction of adenosine from urine followed by electrospray ion mobility spectrometry

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Reusable light-emitting-diode induced chemiluminescence aptasensor for highly sensitive and selective detection of riboflavin

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Duplicative and unnecessary regulation of LDTs will hamper diagnostic innovation

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Use of magnetic beads in selection and detection of biotoxin aptamers by electrochemiluminescence and enzymatic methods

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A single DNA aptamer functions as a biosensor for ricin

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Dynamics and visualization of MCF7 adenocarcinoma cell death by aptamer-C1q-mediated membrane attack

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Aptamers: an emerging class of molecules that rival antibodies in diagnostics

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12 December 2020

10.3390/MOLECULES20046866

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25913927%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25913927%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

25913927

1 reference