Ascochlorin suppresses TGF-β1-induced PAI-1 expression through the inhibition of phospho-EGFR in rat kidney fibroblast cells (Q38470130)

3 September 2017

title

Ascochlorin suppresses TGF-β1-induced PAI-1 expression through the inhibition of phospho-EGFR in rat kidney fibroblast cells (English)

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3 September 2017

Hyun-Ji Cho

1

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3 September 2017

Jeong-Han Kang

2

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3 September 2017

Ji-Hak Jeong

3

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3 September 2017

Yun-Jeong Jeong

4

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3 September 2017

Kwan-Kyu Park

5

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3 September 2017

Yoon-Yub Park

6

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3 September 2017

Yong-Suk Moon

7

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3 September 2017

Hong-Tae Kim

8

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3 September 2017

Il-Kyung Chung

9

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3 September 2017

Cheorl-Ho Kim

10

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3 September 2017

Hyeun-Wook Chang

11

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3 September 2017

Young-Chae Chang

12

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3 September 2017

publication date

23 September 2011

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Molecular Biology Reports

3 September 2017

published in

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3 September 2017

volume

39

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3 September 2017

issue

4

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3 September 2017

page(s)

4597-4603

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https://scigraph.springernature.com/pub.10.1007/s11033-011-1251-y

3 September 2017

exact match

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Upregulation of PAI-1 is mediated through TGF-beta/Smad pathway in transplant arteriopathy

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Suppression of PAI-1 expression through inhibition of the EGFR-mediated signaling cascade in rat kidney fibroblast by ascofuranone

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Plasminogen activator inhibitor type 1 is a potential target in renal fibrogenesis

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Epithelial monolayer wounding stimulates binding of USF-1 to an E-box motif in the plasminogen activator inhibitor type 1 gene

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Antitumor and antimetastatic activity of an antibiotic, ascofuranone, and activation of phagocytes

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Transcription factor decoy for AP-1 reduces mesangial cell proliferation and extracellular matrix production in vitro and in vivo

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Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms

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Ascochlorin inhibits matrix metalloproteinase-9 expression by suppressing activator protein-1-mediated gene expression through the ERK1/2 signaling pathway: inhibitory effects of ascochlorin on the invasion of renal carcinoma cells

21 January 2018

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Ascochlorin suppresses oxLDL-induced MMP-9 expression by inhibiting the MEK/ERK signaling pathway in human THP-1 macrophages

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent

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Plasminogen activator inhibitor-1 and diabetic nephropathy.

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12 December 2020

p53-independent induction of G1 arrest and p21WAF1/CIP1 expression by ascofuranone, an isoprenoid antibiotic, through downregulation of c-Myc

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12 December 2020

In vitro effects of an antitumor antibiotic, ascofuranone, on the murine immune system

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12 December 2020

Alteration of cholesterol metabolism by 4‐0‐methylascochlorin in rats

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12 December 2020

Effect of plasminogen activator inhibitor-1 in diabetes mellitus and cardiovascular disease

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12 December 2020

TGF-beta1 activates MAP kinase in human mesangial cells: a possible role in collagen expression

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12 December 2020

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

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12 December 2020

Expression of urokinase-type plasminogen activator, urokinase-type plasminogen activator receptor and plasminogen activator inhibitors in patients with renal cell carcinoma: correlation with tumor associated macrophage and prognosis

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12 December 2020

Ascochlorin, an isoprenoid antibiotic, induces G1 arrest via downregulation of c-Myc in a p53-independent manner

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12 December 2020

An ascochlorin derivative, AS-6, reduces insulin resistance in the genetically obese diabetic mouse, db/db.

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12 December 2020

Isolation and structure of ascofuranone and ascofranol, antibiotics with hypolipidemic activity.

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12 December 2020

Hypolipidemic property of ascofuranone

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12 December 2020

Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression

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12 December 2020

A quantifiable in vitro model to assess effects of PAI-1 gene targeting on epithelial cell motility

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12 December 2020

10.1007/S11033-011-1251-Y

Identifiers

DOI

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Dimensions Publication ID

3 September 2017

1044496371

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