Telomere dysfunction drives chromosomal instability in human mammary epithelial cells. (Q38472856)

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4 January 2020

title

Telomere dysfunction drives chromosomal instability in human mammary epithelial cells (English)

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4 January 2020

5

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4 January 2020

Anna Genesca

2

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4 January 2020

Josep Egozcue i Cuixart

4

object named as

Josep Egozcue

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4 January 2020

author name string

David Soler

1

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4 January 2020

Gema Arnedo

3

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publication date

1 December 2005

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Genes, Chromosomes and Cancer

4 January 2020

published in

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4 January 2020

volume

44

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issue

4

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4 January 2020

page(s)

339-350

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Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

4 January 2020

cites work

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Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

21 January 2018

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Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

21 January 2018

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7 January 2021

Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells

1 reference

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

7 January 2021

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation

1 reference

7 January 2021

In situ analyses of genome instability in breast cancer

1 reference

7 January 2021

Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program

1 reference

7 January 2021

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

7 January 2021

Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines.

1 reference

7 January 2021

The shortest telomeres drive karyotype evolution in transformed cells

1 reference

7 January 2021

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres

1 reference

7 January 2021

Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors

1 reference

7 January 2021

Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity

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7 January 2021

Telomere dysfunction increases mutation rate and genomic instability

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7 January 2021

Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

7 January 2021

The telomere hypothesis of cellular aging

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7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

7 January 2021

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

1 reference

7 January 2021

Alternative lengthening of telomeres in mammalian cells

1 reference

7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1 reference

7 January 2021

Heterogeneity in telomere length of human chromosomes.

1 reference

7 January 2021

Shortened telomeres join to DNA breaks interfering with their correct repair.

1 reference

7 January 2021

Radiation-induced chromosome breaks in ataxia-telangiectasia cells remain open.

1 reference

7 January 2021

Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis

1 reference

7 January 2021

Regulation of vimentin expression in cultured human mammary epithelial cells

1 reference

7 January 2021

Telomere dysfunction provokes regional amplification and deletion in cancer genomes.

1 reference

7 January 2021

Non-disjunction and Chromosome Loss in Gamma-Irradiated Human Lymphocytes: A FluorescenceIn SituHybridization Analysis Using Centromere-Specific Probes

1 reference

7 January 2021

Detection of chromosomal imbalances in papillary bladder tumors by comparative genomic hybridization

1 reference

7 January 2021

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

1 reference

7 January 2021

A survey of telomerase activity in human cancer

1 reference

7 January 2021

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

1 reference

7 January 2021

Isolation and growth of human mammary epithelial cells

1 reference

7 January 2021

Cytogenetic clues to breast carcinogenesis

1 reference

7 January 2021

Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism?

1 reference

7 January 2021

Identifiers

DOI

10.1002/GCC.20244

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4 January 2020

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