In vitro studies of the genotoxicity of ionizing radiation in human G(0) T lymphocytes (Q38474141)

3 September 2017

title

In vitro studies of the genotoxicity of ionizing radiation in human G(0) T lymphocytes (English)

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3 September 2017

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Patrick O'Neill

1

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3 September 2017

Janice Nicklas

2

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3 September 2017

Betsy Hirsch

3

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3 September 2017

Rick Jostes

4

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3 September 2017

Timothy Hunter

5

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3 September 2017

Linda Sullivan

6

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3 September 2017

Richard Albertini

7

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3 September 2017

publication date

1 December 2005

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Environmental and Molecular Mutagenesis

3 September 2017

published in

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3 September 2017

volume

46

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3 September 2017

issue

4

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3 September 2017

page(s)

207-220

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Genetic instability in human T-lymphocytes

3 September 2017

cites work

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Molecular analysis of hypoxanthine phosphoribosyltransferase gene deletions induced by alpha- and X-radiation in human lymphoblastoid cells

21 January 2018

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International Commission for Protection Against Environmental Mutagens and Carcinogens. Working paper no. 3. Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo

21 January 2018

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Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age.

21 January 2018

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An explanation of interspecific differences in sensitivity to X-ray-induced chromosome aberrations and a consideration of dose-response curves

21 January 2018

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The effect of cytosine arabinoside on the frequency of single-strand breaks in DNA of mammalian cells following irradiation or chemical treatment

21 January 2018

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Analysis of mutational effects at the HPRT locus in human G(0) phase lymphocytes irradiated in vitro with gamma rays

21 January 2018

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In vivo ionizing irradiations produce deletions in the hprt gene of human T-lymphocytes

21 January 2018

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X-ray induction of 6-thioguanine-resistant mutants in division arrested, G0/G1 phase Chinese hamster ovary cells.

21 January 2018

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An analysis of in vivo hprt mutant frequency in circulating T-lymphocytes in the normal human population: a comparison of four datasets

21 January 2018

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Ionizing radiation and genetic risks. XIII. Summary and synthesis of papers VI to XII and estimates of genetic risks in the year 2000.

21 January 2018

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Chromosome aberrations induced in human lymphocytes by in vitro and in vivo X-rays.

21 January 2018

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Enumeration of 6-thioguanine-resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo

21 January 2018

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T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood

21 January 2018

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7 January 2021

Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes.

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7 January 2021

Identification of potential mRNA biomarkers in peripheral blood lymphocytes for human exposure to ionizing radiation.

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7 January 2021

Monitoring human radiation exposure by gene expression profiling: possibilities and pitfalls.

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7 January 2021

M-FISH analysis shows that complex chromosome aberrations induced by alpha -particle tracks are cumulative products of localized rearrangements

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7 January 2021

Types and rates of x-ray-induced chromosome aberrations in human blood irradiated in vitro

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7 January 2021

Ionizing radiation-induced 6-thioguanine-resistant clones in synchronous CHO cells.

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7 January 2021

Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

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7 January 2021

Emergence of genetic instability in children treated for leukemia.

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7 January 2021

Identification of a duplication of Xq28 associated with bilateral periventricular nodular heterotopia

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7 January 2021

Identification of mutations leading to the Lesch-Nyhan syndrome by automated direct DNA sequencing of in vitro amplified cDNA.

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7 January 2021

Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families

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7 January 2021

Expression of the oxidative base excision repair enzymes is not induced in TK6 human lymphoblastoid cells after low doses of ionizing radiation.

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7 January 2021

Total gene deletions and mutant frequency of the HPRT gene as indicators of radiation exposure in Chernobyl liquidators

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7 January 2021

X-ray induction of 8-azaguanine-resistant mutants in synchronous Chinese hamster ovary cells.

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7 January 2021

In vitro exposure of mammalian cells to radon: dosimetric considerations

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7 January 2021

A chromosome study of 6-thioguanine-resistant mutants in T lymphocytes of Hiroshima atomic bomb survivors.

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7 January 2021

Fluorescence in situ hybridization of YAC clones after Alu-PCR amplification

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7 January 2021

Physical mapping of the human hprt chromosomal region (Xq26)

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7 January 2021

Pulsed field analysis of hprt T-cell large deletions: telomeric region breakpoint spectrum

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7 January 2021

DNA repair capacity after gamma-irradiation and expression profiles of DNA repair genes in resting and proliferating human peripheral blood lymphocytes.

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7 January 2021

Genetic damage induced by in vitro irradiation of human G0 lymphocytes with low-energy protons (28 keV/microm): HPRT mutations and chromosome aberrations

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7 January 2021

Measurement of in vivo mutations in human lymphocytes

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7 January 2021

Molecular analyses of in vivo hprt mutations in human T-lymphocytes. I. Studies of low frequency 'spontaneous' mutants by Southern blots

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7 January 2021

Molecular analyses of in vivo hprt mutations in human T-lymphocytes. III. Longitudinal study of hprt gene structural alterations and T-cell clonal origins

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7 January 2021

Molecular analysis of in vivo hprt mutations in human T lymphocytes. V. Effects of total body irradiation secondary to radioimmunoglobulin therapy (RIT)

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7 January 2021

Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans.

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7 January 2021

In vitro induction, expression and selection of thioguanine-resistant mutants with human T-lymphocytes.

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7 January 2021

Southern-blot analyses of human T-lymphocyte mutants induced in vitro by gamma-irradiation.

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7 January 2021

Cytosine arabinoside enhancement of gamma irradiation induced mutations in human T-lymphocytes

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7 January 2021

The effect of T-lymphocyte ‘clonality’ on the calculated hprt mutation frequency occurring in vivo in humans

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7 January 2021

The effect of cytosine arabinoside on the frequency of X-ray-induced chromosome aberrations in normal human leukocytes

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7 January 2021

Mechanisms of induction of specific chromosomal alterations

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7 January 2021

Breakpoints and junctional regions of intragenic deletions in the HPRT gene in human T-Cells

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7 January 2021

hprt mutant frequencies, nonpulmonary malignancies, and domestic radon exposure: "postmortem" analysis of an interesting hypothesis

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7 January 2021

High-resolution cytogenetic analysis of X-ray induced mutations of the HPRT gene of primary human fibroblasts

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7 January 2021

Recovery from lethal and mutagenic damage during postirradiation holding and low-dose-rate irradiations of cultured hamster cells.

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7 January 2021

Induction and decline of HPRT mutants and deletions following a low dose radiation exposure at Chernobyl

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7 January 2021

Use of inverse PCR to amplify and sequence breakpoints of HPRT deletion and translocation mutations.

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7 January 2021

Molecular analysis and comparison of radiation-induced large deletions of the HPRT locus in primary human skin fibroblasts

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7 January 2021

Identifiers

DOI

10.1002/EM.20143

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3 September 2017

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