A sexually dimorphic hypothalamic response to chronic high-fat diet consumption (Q38527551)

3 September 2017

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title

A sexually dimorphic hypothalamic response to chronic high-fat diet consumption (English)

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3 September 2017

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E Morselli

1

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3 September 2017

A P Frank

2

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3 September 2017

B F Palmer

3

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3 September 2017

C Rodriguez-Navas

4

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3 September 2017

A Criollo

5

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3 September 2017

D J Clegg

6

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3 September 2017

language of work or name

English

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publication date

15 June 2015

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International Journal of Obesity

3 September 2017

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3 September 2017

40

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3 September 2017

2

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3 September 2017

206-209

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https://scigraph.springernature.com/pub.10.1038/ijo.2015.114

3 September 2017

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cites work

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Increased adipose tissue in male and female estrogen receptor-alpha knockout mice

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Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man

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Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction

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Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome.

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Diet-induced metabolic disturbances as modulators of brain homeostasis

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Inflammation and metabolic disorders

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Obesity is associated with hypothalamic injury in rodents and humans

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Brain-derived estrogen exerts anti-inflammatory and neuroprotective actions in the rat hippocampus

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17β-Oestradiol anti-inflammatory effects in primary astrocytes require oestrogen receptor β-mediated neuroglobin up-regulation

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Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα.

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Ceramides in insulin resistance and lipotoxicity

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An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

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Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance

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Consumption of a high-fat diet, but not regular endurance exercise training, regulates hypothalamic lipid accumulation in mice.

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Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

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The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis

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Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

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The nuclear receptor coactivator PGC-1alpha exhibits modes of interaction with the estrogen receptor distinct from those of SRC-1.

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Cognitive enhancement by omega-3 fatty acids from child-hood to old age: findings from animal and clinical studies

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Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment

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Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease

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Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study.

21 January 2018

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Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults

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17β-estradiol and inflammation: implications for ischemic stroke

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PubMed

https://pubmed.ncbi.nlm.nih.gov/26073655

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sex differences in lipid metabolism and metabolic disease risk

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26073655

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26073655

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/IJO.2015.114

1 reference

Dimensions Publication ID

3 September 2017

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1 reference