Sepsis-induced immune alterations monitoring by flow cytometry as a promising tool for individualized therapy (Q38541110)

4 September 2017

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title

Sepsis-induced immune alterations monitoring by flow cytometry as a promising tool for individualized therapy (English)

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4 September 2017

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2

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author name string

Guillaume Monneret

series ordinal

1

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4 September 2017

publication date

30 June 2015

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Cytometry Part B: Clinical Cytometry

4 September 2017

published in

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4 September 2017

volume

90

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4 September 2017

issue

4

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4 September 2017

page(s)

376-386

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describes a project that uses

4 September 2017

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Sepsis: current dogma and new perspectives

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Critical care and the global burden of critical illness in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Epidemiology and economic evaluation of severe sepsis in France: age, severity, infection site, and place of acquisition (community, hospital, or intensive care unit) as determinants of workload and cost.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

The new normal: immunomodulatory agents against sepsis immune suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Sepsis definitions: time for change

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony

21 January 2018

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Disease tolerance as a defense strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Monitoring the immune response in sepsis: a rational approach to administration of immunoadjuvant therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

The late phase of sepsis is characterized by an increased microbiological burden and death rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Normal responses to injury prevent systemic inflammation and can be immunosuppressive

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

21 January 2018

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Immunotherapy for sepsis--a new approach against an ancient foe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

A genomic storm in critically injured humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Macroscopic postmortem findings in 235 surgical intensive care patients with sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

ICU-acquired immunosuppression and the risk for secondary fungal infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Reactivation of multiple viruses in patients with sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Persistent lymphopenia after diagnosis of sepsis predicts mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Long-term outcomes from sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Long-term mortality after community-acquired sepsis: a longitudinal population-based cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Sepsis affects most routine and cell population data (CPD) obtained using the Sysmex XN-2000 blood cell analyzer: neutrophil-related CPD NE-SFL and NE-WY provide useful information for detecting sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Fraction of immature granulocytes reflects severity but not mortality in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Circulating Immature Granulocytes With T-Cell Killing Functions Predict Sepsis Deterioration*

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Changes in dendritic cell function in the immune response to sepsis. Cell- & tissue-based therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Bench-to-bedside review: endotoxin tolerance as a model of leukocyte reprogramming in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Determining the degree of immunodysregulation in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Endotoxin tolerance: new mechanisms, molecules and clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Decreased expression of the fractalkine receptor CX3CR1 on circulating monocytes as new feature of sepsis-induced immunosuppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Immunosuppression in patients who die of sepsis and multiple organ failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Immunoparalysis in patients with severe trauma and the effect of inhaled interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Dysfunction of alveolar macrophages after cardiac surgery and postoperative pneumonia?--An observational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Monitoring temporary immunodepression by flow cytometric measurement of monocytic HLA-DR expression: a multicenter standardized study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Preliminary results in quantitation of HLA-DRA by real-time PCR: a promising approach to identify immunosuppression in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Monocyte HLA-DR in sepsis: shall we stop following the flow?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Susceptibility to programmed cell death in T-lymphocytes from septic patients: a mechanism for lymphopenia and Th2 predominance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Depressed interleukin-12-producing activity by monocytes correlates with adverse clinical course and a shift toward Th2-type lymphocyte pattern in severely injured male trauma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Prevention of lymphocyte apoptosis--a potential treatment of sepsis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Early assessment of leukocyte alterations at diagnosis of septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Increased MerTK expression in circulating innate immune cells of patients with septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Decreased T-cell repertoire diversity in sepsis: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Reduction of immunocompetent T cells followed by prolonged lymphopenia in severe sepsis in the elderly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Severe lymphopenia is associated with elevated plasma interleukin-15 levels and increased mortality during severe sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

The role of natural killer cells in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Natural killer (NK) cells in antibacterial innate immunity: angels or devils?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Phenotype and functions of natural killer cells in critically-ill septic patients

21 January 2018

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Lymphocyte subset numbers depend on the bacterial origin of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Early changes of CD4-positive lymphocytes and NK cells in patients with severe Gram-negative sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Viral infections in the ICU.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Cytomegalovirus reactivation in critically ill immunocompetent hosts: a decade of progress and remaining challenges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Both percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Characterisation of gamma delta (γδ) T cell populations in patients with sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Impact of sepsis on CD4 T cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Flow cytometric evaluation of lymphocyte transformation test based on 5-ethynyl-2'deoxyuridine incorporation as a clinical alternative to tritiated thymidine uptake measurement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

STAT5 phosphorylation in T cell subsets from septic patients in response to recombinant human interleukin-7: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Marked elevation of human circulating CD4+CD25+ regulatory T cells in sepsis-induced immunoparalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Up-regulation of programmed cell death 1 ligand 1 on neutrophils may be involved in sepsis-induced immunosuppression: an animal study and a prospective case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Blockade of the T cell immunoglobulin and mucin domain protein 3 pathway exacerbates sepsis-induced immune deviation and immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

B and T lymphocyte attenuator expression on CD4+ T-cells associates with sepsis and subsequent infections in ICU patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Prognostic value of CD4(+)CD25(+) Tregs as a valuable biomarker for patients with sepsis in ICU.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

High circulating CD39(+) regulatory T cells predict poor survival for sepsis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

IL-7 modulates in vitro and in vivo human memory T regulatory cell functions through the CD39/ATP axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Postoperative immunosuppression after open and laparoscopic liver resection: assessment of cellular immune function and monocytic HLA-DR expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Blockade of PD1 and TIM3 restores innate and adaptive immunity in patients with acute alcoholic hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Surgical and physical stress increases circulating blood dendritic cell counts independently of monocyte counts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

CD4+ T-lymphocyte alterations in trauma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Increased regulatory T cells in patients with liver cirrhosis correlated with hyperbilirubinemia and predict bacterial complications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Percentages of CD4+ T regulatory cells and HLA-DR expressing monocytes in severe intra-abdominal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Subsequent infections in survivors of sepsis: epidemiology and outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Immunosuppressive CD14+HLA-DR(low)/- monocytes in B-cell non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Human leukocyte antigen-DR expression on peripheral blood monocytes and the risk of pneumonia in pediatric lung transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Patterns of monocyte subpopulations and their surface expression of HLA-DR during adverse events after hematopoietic stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Variation in the human immune system is largely driven by non-heritable influences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

Decreased response to recall antigens is associated with depressed costimulatory receptor expression in septic critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

A model to compute the medical cost of patients in intensive care

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Nosocomial infection after septic shock among intensive care unit patients

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Long-term (10-year) mortality of younger previously healthy patients with severe sepsis/septic shock is worse than that of patients with nonseptic critical illness and of the general population

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

TLR3 agonist improves survival to secondary pneumonia in a double injury model

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Depletion of dendritic cells, but not macrophages, in patients with sepsis

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https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Decrease in circulating dendritic cells predicts fatal outcome in septic shock

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Flow cytometric analysis of peripheral blood dendritic cells in patients with severe sepsis

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Immune monitoring of patients with septic shock by measurement of intraleukocyte cytokines

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Expression of MHC class II molecules contributes to lipopolysaccharide responsiveness

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Increased IL-10 production and HLA-DR suppression in the lungs of injured patients precede the development of nosocomial pneumonia

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Reversal of immunoparalysis by recombinant human granulocyte-macrophage colony-stimulating factor in patients with severe sepsis

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Inter-laboratory assessment of flow cytometric monocyte HLA-DR expression in clinical samples

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD25- lymphocytes.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Circulating dendritic cells following burn

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Monocyte HLA-DR expression as predictor of poor outcome in neonates with late onset neonatal sepsis

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Impairment of monocyte functions in advanced head and neck cancer

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.B.21270

7 January 2021

Identifiers

DOI

10.1002/CYTO.B.21270

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4 September 2017

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