MicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer (Q38550157)

4 September 2017

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title

MicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer (English)

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4 September 2017

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2

Syed Kashif Zaidi

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4 September 2017

Mohammad Alam Jafri

1

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4 September 2017

Shakeel Ahmed Ansari

series ordinal

3

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4 September 2017

Mohammed Hussein Al-Qahtani

series ordinal

4

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4 September 2017

Jerry W Shay

series ordinal

5

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4 September 2017

language of work or name

English

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publication date

18 July 2015

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Expert Opinion on Therapeutic Targets

4 September 2017

published in

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4 September 2017

volume

19

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4 September 2017

issue

12

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4 September 2017

page(s)

1705-1723

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4 September 2017

cites work

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MicroRNA genes are transcribed by RNA polymerase II

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Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

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Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

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MicroRNA: function, detection, and bioanalysis.

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Three classes of genes mutated in colorectal cancers with chromosomal instability

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miRNA expression in colon polyps provides evidence for a multihit model of colon cancer

21 January 2018

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Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types

21 January 2018

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MicroRNA-145: a potent tumour suppressor that regulates multiple cellular pathways

21 January 2018

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MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1

21 January 2018

1 reference

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MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1.

21 January 2018

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Lessons from miR-143/145: the importance of cell-type localization of miRNAs

21 January 2018

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Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer

21 January 2018

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An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration

21 January 2018

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MicroRNA-455 inhibits proliferation and invasion of colorectal cancer by targeting RAF proto-oncogene serine/threonine-protein kinase

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway

21 January 2018

1 reference

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MiR-378 is an independent prognostic factor and inhibits cell growth and invasion in colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-378 is associated with non-small cell lung cancer brain metastasis by promoting cell migration, invasion and tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Identification and functional screening of microRNAs highly deregulated in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

p53 represses c-Myc through induction of the tumor suppressor miR-145

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Epigenetic regulation of microRNA expression in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Up-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-330 regulates the proliferation of colorectal cancer cells by targeting Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Role of miR-143 targeting KRAS in colorectal tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-21: a small multi-faceted RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-149 suppresses colorectal cancer cell migration and invasion by directly targeting forkhead box transcription factor FOXM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Role of microRNA-30c targeting ADAM19 in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Down-regulation of miR-126 is associated with colorectal cancer cells proliferation, migration and invasion by targeting IRS-1 via the AKT and ERK1/2 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-574-5p negatively regulates Qki6/7 to impact β-catenin/Wnt signalling and the development of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA regulation network in colorectal cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

The Regulatory Role of MicroRNAs in EMT and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MiR-34, SIRT1 and p53: the feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-34a repression of SIRT1 regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MiR-194 deregulation contributes to colorectal carcinogenesis via targeting AKT2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Elevated expression of miR-210 predicts poor survival of cancer patients: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miRNA-27b targets vascular endothelial growth factor C to inhibit tumor progression and angiogenesis in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Role of miRNA-146a in the regulation of the innate immune response and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-146a and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MiR-146a in Immunity and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNAs and inflammation in the pathogenesis and progression of colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Modulation of tumorigenesis by the pro-inflammatory microRNA miR-301a in mouse models of lung cancer and colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Circulating miR‐221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Recurrence of early stage colon cancer predicted by expression pattern of circulating microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

The expression of microRNA-375 in plasma and tissue is matched in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Serum microRNA panel as biomarkers for early diagnosis of colorectal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Circulating exosomal microRNAs as biomarkers of colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA Expression Profiling of Exfoliated Colonocytes Isolated from Feces for Colorectal Cancer Screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Targeting microRNAs in cancer: rationale, strategies and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA silencing in primates: towards development of novel therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

The Promise of MicroRNA Replacement Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

let-7 microRNA functions as a potential growth suppressor in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-133b regulates the MET proto-oncogene and inhibits the growth of colorectal cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Putative tumor suppressor miR‐145 inhibits colon cancer cell growth by targeting oncogene friend leukemia virus integration 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

In vivo delivery of miRNAs for cancer therapy: challenges and strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Systemic delivery of microRNA-34a for cancer stem cell therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Systemic delivery of miR-126 by miRNA-loaded Bubble liposomes for the treatment of hindlimb ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

MicroRNA-141 regulates Smad interacting protein 1 (SIP1) and inhibits migration and invasion of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

Prognostic significance of miR-215 in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1069816

10.1517/14728222.2015.1069816

21 January 2018

Identifiers

DOI

1 reference

4 September 2017

1 reference