Bat-to-human: spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond (Q38553361)

4 September 2017

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22 October 2022

Bat-to-human: spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond (English)

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Middle East respiratory syndrome coronavirus

4 September 2017

main subject

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3

George F Gao

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4 September 2017

Guangwen Lu

1

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4 September 2017

Qihui Wang

series ordinal

2

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4 September 2017

publication date

21 July 2015

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4 September 2017

1 August 2015

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22 October 2022

Trends in Microbiology

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4 September 2017

22 October 2022

23

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4 September 2017

issue

8

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4 September 2017

page(s)

468-478

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Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

4 September 2017

cites work

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12 December 2020

Hospital outbreak of Middle East respiratory syndrome coronavirus

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Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission

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Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome Coronavirus

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Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection

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Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study.

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Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation

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Pathways of cross-species transmission of synthetically reconstructed zoonotic severe acute respiratory syndrome coronavirus

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Angiotensin-converting enzyme 2 (ACE2) from raccoon dog can serve as an efficient receptor for the spike protein of severe acute respiratory syndrome coronavirus.

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12 December 2020

CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes.

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12 December 2020

Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study

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12 December 2020

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein

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12 December 2020

Middle East respiratory syndrome coronavirus (MERS-CoV) RNA and neutralising antibodies in milk collected according to local customs from dromedary camels, Qatar, April 2014.

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12 December 2020

Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4.

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12 December 2020

Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirus

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12 December 2020

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

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12 December 2020

Proteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.

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12 December 2020

Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor

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12 December 2020

Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-CoV entry

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12 December 2020

Point mutations in the S protein connect the sialic acid binding activity with the enteropathogenicity of transmissible gastroenteritis coronavirus

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Structural biology. Adaptation of SARS coronavirus to humans

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Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China

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Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.

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12 December 2020

Structural Analysis of Major Species Barriers between Humans and Palm Civets for Severe Acute Respiratory Syndrome Coronavirus Infections

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12 December 2020

Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26

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12 December 2020

Family cluster of Middle East respiratory syndrome coronavirus infections

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12 December 2020

Adaptive evolution of bat dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus

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12 December 2020

Molecular diversity of coronaviruses in bats.

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12 December 2020

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

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12 December 2020

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

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12 December 2020

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

1 reference

12 December 2020

Rooting the phylogenetic tree of middle East respiratory syndrome coronavirus by characterization of a conspecific virus from an African bat

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12 December 2020

Receptor for mouse hepatitis virus is a member of the carcinoembryonic antigen family of glycoproteins

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12 December 2020

Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

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12 December 2020

Evidence for a common evolutionary origin of coronavirus spike protein receptor-binding subunits

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12 December 2020

Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus

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12 December 2020

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

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12 December 2020

Conformational reorganization of the SARS coronavirus spike following receptor binding: implications for membrane fusion

1 reference

12 December 2020

Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2.

1 reference

12 December 2020

Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites

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12 December 2020

Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

1 reference

12 December 2020

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

1 reference

12 December 2020

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

1 reference

12 December 2020

The molecular biology of coronaviruses

1 reference

12 December 2020

Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion peptide

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12 December 2020

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

1 reference

12 December 2020

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

1 reference

12 December 2020

Crystal Structure of the Receptor-Binding Domain from Newly Emerged Middle East Respiratory Syndrome Coronavirus

1 reference

12 December 2020

Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa

1 reference

12 December 2020

Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus in bats, Saudi Arabia

1 reference

12 December 2020

SARS-CoV and emergent coronaviruses: viral determinants of interspecies transmission

1 reference

12 December 2020

Molecular architecture of the bipartite fusion loops of vesicular stomatitis virus glycoprotein G, a class III viral fusion protein.

1 reference

12 December 2020

The S protein of bovine coronavirus is a hemagglutinin recognizing 9-O-acetylated sialic acid as a receptor determinant

1 reference

12 December 2020

Architecture of the SARS coronavirus prefusion spike

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus quasispecies that include homologues of human isolates revealed through whole-genome analysis and virus cultured from dromedary camels in Saudi Arabia

1 reference

12 December 2020

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor

1 reference

12 December 2020

Infection with MERS-CoV causes lethal pneumonia in the common marmoset

1 reference

12 December 2020

Protease inhibitors targeting coronavirus and filovirus entry

1 reference

12 December 2020

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

1 reference

12 December 2020

Structural and functional analysis of the surface protein of human coronavirus OC43.

1 reference

12 December 2020

Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core

1 reference

12 December 2020

Modulation of TNF-alpha-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-alpha production and facilitates viral entry

1 reference

12 December 2020

Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus

1 reference

12 December 2020

Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe

1 reference

12 December 2020

A review of studies on animal reservoirs of the SARS coronavirus

1 reference

12 December 2020

Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors

1 reference

12 December 2020

Rapid generation of a mouse model for Middle East respiratory syndrome

1 reference

12 December 2020

Tropism and replication of Middle East respiratory syndrome coronavirus from dromedary camels in the human respiratory tract: an in-vitro and ex-vivo study.

1 reference

12 December 2020

Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro

1 reference

12 December 2020

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12 December 2020

Planning for epidemics--the lessons of SARS.

1 reference

12 December 2020

Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines

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12 December 2020

NMR structures and localization of the potential fusion peptides and the pre-transmembrane region of SARS-CoV: Implications in membrane fusion.

1 reference

12 December 2020

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

1 reference

12 December 2020

Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection

1 reference

12 December 2020

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

1 reference

12 December 2020

Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.

1 reference

12 December 2020

Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2012)

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12 December 2020

Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.

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12 December 2020

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

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12 December 2020

Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.

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12 December 2020

Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolution

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12 December 2020

Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

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12 December 2020

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

1 reference

12 December 2020

Structure of SARS coronavirus spike receptor-binding domain complexed with receptor

1 reference

12 December 2020

Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface

1 reference

12 December 2020

SARS-like virus in the Middle East: a truly bat-related coronavirus causing human diseases

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution

1 reference

12 December 2020

Protease-mediated enhancement of severe acute respiratory syndrome coronavirus infection

1 reference

12 December 2020

Membrane insertion of the three main membranotropic sequences from SARS-CoV S2 glycoprotein.

1 reference

12 December 2020

ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis

1 reference

12 December 2020

Virology: SARS virus infection of cats and ferrets

1 reference

12 December 2020

Viral fusion proteins: multiple regions contribute to membrane fusion

1 reference

12 December 2020

Sialic acids as receptor determinants for coronaviruses

1 reference

12 December 2020

Evidence for camel-to-human transmission of MERS coronavirus

1 reference

12 December 2020

The Middle East respiratory syndrome coronavirus (MERS-CoV) does not replicate in Syrian hamsters

1 reference

12 December 2020

Type II transmembrane serine proteases in cancer and viral infections.

1 reference

12 December 2020

Atomic structure of a thermostable subdomain of HIV-1 gp41

1 reference

12 December 2020

Interspecies transmission and emergence of novel viruses: lessons from bats and birds

1 reference

12 December 2020

A structural view of coronavirus-receptor interactions

1 reference

12 December 2020

Identification of two critical amino acid residues of the severe acute respiratory syndrome coronavirus spike protein for its variation in zoonotic tropism transition via a double substitution strategy.

1 reference

12 December 2020

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

1 reference

12 December 2020

Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation

1 reference

12 December 2020

Mechanisms of viral membrane fusion and its inhibition

1 reference

12 December 2020

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease

1 reference

12 December 2020

Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion

1 reference

12 December 2020

Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013.

1 reference

12 December 2020

Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

1 reference

12 December 2020

Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide

1 reference

12 December 2020

Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013.

1 reference

12 December 2020

Bats are natural reservoirs of SARS-like coronaviruses

1 reference

12 December 2020

Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.

1 reference

12 December 2020

Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

1 reference

12 December 2020

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

1 reference

12 December 2020

Fusion peptides and the mechanism of viral fusion

1 reference

12 December 2020

Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium

1 reference

12 December 2020

10.1016/J.TIM.2015.06.003

Identifiers

DOI

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4 September 2017

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