Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges. (Q38560476)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

review article

1 reference

title

Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

main subject

inflammation

0 references

myocardial infarction

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Nikolaos G Frangogiannis

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Amit Saxena

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

publication date

17 July 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

published in

Translational Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

167

1 reference

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20 February 2020

issue

1

1 reference

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20 February 2020

page(s)

152-166

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

Necrotic myocardial cells release damage-associated molecular patterns that provoke fibroblast activation in vitro and trigger myocardial inflammation and fibrosis in vivo.

20 February 2020

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6 September 2017

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23 June 2018

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Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction

23 June 2018

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Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction.

23 June 2018

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Factors modifying protective effect of anti-CD18 antibodies on myocardial reperfusion injury in dogs.

23 June 2018

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The alpha-smooth muscle actin-positive cells in healing human myocardial scars

23 June 2018

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Neutrophil accumulation in experimental myocardial infarcts: relation with extent of injury and effect of reperfusion.

23 June 2018

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The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis. The MILIS Study Group

23 June 2018

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Deleterious effects of methylprednisolone in patients with myocardial infarction

23 June 2018

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The reparative function of cardiomyocytes in the infarcted myocardium.

23 June 2018

1 reference

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Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot studies).

31 August 2018

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Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.

31 August 2018

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Foxp3+ CD4+ T cells improve healing after myocardial infarction by modulating monocyte/macrophage differentiation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Regeneration of chronic myocardial infarction by injectable hydrogels containing stem cell homing factor SDF-1 and angiogenic peptide Ac-SDKP.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Macrophage subpopulations are essential for infarct repair with and without stem cell therapy.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Effects of the P-selectin antagonist inclacumab on myocardial damage after percutaneous coronary intervention for non-ST-segment elevation myocardial infarction: results of the SELECT-ACS trial

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Interleukin-1β blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouse

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Detrimental effect of fractalkine on myocardial ischaemia and heart failure.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

CC chemokine CCL5 plays a central role impacting infarct size and post-infarction heart failure in mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Lowering interleukin-1 activity with anakinra improves myocardial deformation in rheumatoid arthritis.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Inhibition of interleukin-1 by anakinra improves vascular and left ventricular function in patients with rheumatoid arthritis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Antagonism of stromal cell-derived factor-1alpha reduces infarct size and improves ventricular function after myocardial infarction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Monocyte chemotactic protein-3 is a myocardial mesenchymal stem cell homing factor.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

31 August 2018

Yin and yang of MCP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

CCL2/Monocyte Chemoattractant Protein-1 regulates inflammatory responses critical to healing myocardial infarcts.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Anti-Monocyte Chemoattractant Protein-1 Gene Therapy Attenuates Left Ventricular Remodeling and Failure After Experimental Myocardial Infarction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: the results of the HALT-MI study

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Inhibition of interleukin-8 blocks myocardial ischemia-reperfusion injury.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

An anti-CD18 antibody limits infarct size and preserves left ventricular function in dogs with ischemia and 48-hour reperfusion.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

A chimeric IgG4 monoclonal antibody directed against CD18 reduces infarct size in a primate model of myocardial ischemia and reperfusion.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Induction of interleukin-6 synthesis in the myocardium. Potential role in postreperfusion inflammatory injury.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Ibuprofen-mediated infarct size reduction: effects on regional myocardial function in canine myocardial infarction in canine myocardial infarction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Ibuprofen inhibits granulocyte responses to inflammatory mediators. A proposed mechanism for reduction of experimental myocardial infarct size

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Mummification of the infarcted myocardium by high dose corticosteroids

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myoc

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

A New Monocyte Chemotactic Protein-1/Chemokine CC Motif Ligand-2 Competitor Limiting Neointima Formation and Myocardial Ischemia/Reperfusion Injury in Mice

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

Single Administration of the CXC Chemokine-Binding Protein Evasin-3 During Ischemia Prevents Myocardial Reperfusion Injury in Mice

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4684426

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

3 December 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Chemokines in ischemia and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Myofibroblasts in reperfused myocardial infarcts express the embryonic form of smooth muscle myosin heavy chain (SMemb)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Critical role of endogenous thrombospondin-1 in preventing expansion of healing myocardial infarcts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Indomethacin-induced scar thinning after experimental myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Relation between use of anti-inflammatory agents and left ventricular free wall rupture during acute myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Cardioprotective actions of a monoclonal antibody against CD-18 in myocardial ischemia-reperfusion injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Sustained limitation of myocardial reperfusion injury by a monoclonal antibody that alters leukocyte function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

An anti-CD11/CD18 monoclonal antibody in patients with acute myocardial infarction having percutaneous transluminal coronary angioplasty (the FESTIVAL study)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Stem cell factor induction is associated with mast cell accumulation after canine myocardial ischemia and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Ischemia-reperfusion of rat myocardium activates nuclear factor-KappaB and induces neutrophil infiltration via lipopolysaccharide-induced CXC chemokine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

The stromal cell-derived factor-1/CXCR4 axis in cardiac injury and repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

Impact of diastolic dysfunction on the development of heart failure in diabetic patients after acute myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2015.07.002

VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26241027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TRSL.2015.07.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26241027%20AND%20SRC:MED&resulttype=core&format=json