Biology of p62/sequestosome-1 in Age-Related Macular Degeneration (AMD). (Q38596839)

4 September 2017

title

Biology of p62/sequestosome-1 in Age-Related Macular Degeneration (AMD). (English)

1 reference

4 September 2017

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26427388%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Katayoon B Ebrahimi

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26427388%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Michelle Chyn

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26427388%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Marisol Cano

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26427388%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

James T Handa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26427388%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

1 January 2016

1 reference

Advances in Experimental Medicine and Biology

4 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26427388%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

854

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4 June 2020

page(s)

17-22

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

4 June 2020

cites work

1 reference

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Nerve cells immunoreactive for p62 in select hypothalamic and brainstem nuclei of controls and Parkinson's disease cases

31 March 2020

1 reference

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Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration

31 March 2020

1 reference

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Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells.

31 March 2020

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ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2

31 March 2020

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A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice.

31 March 2020

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Oxidative damage to the promoter region of SQSTM1/p62 is common to neurodegenerative disease

31 March 2020

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Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease

31 March 2020

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Mechanisms underlying inflammation in neurodegeneration

31 March 2020

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Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2

31 March 2020

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Mutations in the gene encoding p62 in Japanese patients with amyotrophic lateral sclerosis

31 March 2020

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Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy

31 March 2020

1 reference

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p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

31 March 2020

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31 March 2020

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

31 March 2020

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

31 March 2020

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Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation.

31 March 2020

1 reference

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Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins

31 March 2020

1 reference

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PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation

31 March 2020

1 reference

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p62/SQSTM1 enhances NOD2-mediated signaling and cytokine production through stabilizing NOD2 oligomerization

31 March 2020

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Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

31 March 2020

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Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration.

31 March 2020

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A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype.

31 March 2020

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Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease

31 March 2020

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Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

31 March 2020

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Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.

31 March 2020

1 reference

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Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling

31 March 2020

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SIRT1 inactivation induces inflammation through the dysregulation of autophagy in human THP-1 cells

31 March 2020

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Smoking mice: a potential model for studying accumulation of drusen-like material on Bruch's membrane

31 March 2020

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p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium

31 March 2020

1 reference

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