p62 is a key regulator of nutrient sensing in the mTORC1 pathway. (Q38666713)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21981924%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

p62 is a key regulator of nutrient sensing in the mTORC1 pathway (English)

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14 February 2020

2

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14 February 2020

Aleksey Porollo

6

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14 February 2020

author name string

Angeles Duran

1

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14 February 2020

Juan F Linares

3

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14 February 2020

Jayashree Joshi

4

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14 February 2020

Shadi Abu-Baker

5

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14 February 2020

Malene Hansen

7

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14 February 2020

Jorge Moscat

8

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14 February 2020

Maria T Diaz-Meco

9

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publication date

1 October 2011

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14 February 2020

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14 February 2020

volume

44

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14 February 2020

issue

1

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14 February 2020

page(s)

134-146

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Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

14 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E

6 September 2017

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A functional role for the p62-ERK1 axis in the control of energy homeostasis and adipogenesis

6 September 2017

1 reference

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Methods in mammalian autophagy research

6 September 2017

1 reference

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mTOR signaling at a glance

6 September 2017

1 reference

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Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex

6 September 2017

1 reference

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Scaffolds: interaction platforms for cellular signalling circuits.

6 September 2017

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p62 at the crossroads of autophagy, apoptosis, and cancer

6 September 2017

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A role for ubiquitin in selective autophagy

6 September 2017

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Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

6 September 2017

1 reference

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

6 September 2017

1 reference

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Regulation of TORC1 by Rag GTPases in nutrient response

6 September 2017

1 reference

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

6 September 2017

1 reference

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A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

6 September 2017

1 reference

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Defining the role of mTOR in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

Cell signaling and function organized by PB1 domain interactions.

6 September 2017

1 reference

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mTOR and cancer: insights into a complex relationship

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

Growing roles for the mTOR pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

Upstream and downstream of mTOR

6 September 2017

1 reference

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ONCOMINE: a cancer microarray database and integrated data-mining platform

6 September 2017

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190169

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

6 September 2017

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Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B

6 September 2017

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The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

6 September 2017

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Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.

6 September 2017

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RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway

6 September 2017

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Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases

6 September 2017

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To aggregate or not to aggregate? A new role for p62.

6 September 2017

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Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

23 June 2018

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23 June 2018

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31 August 2018

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The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis.

31 August 2018

1 reference

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10.1016/J.MOLCEL.2011.06.038

31 August 2018

Identifiers

DOI

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14 February 2020

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14 February 2020

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