Teratoma: from spontaneous tumors to the pluripotency/malignancy assay (Q38677423)

5 September 2017

title

Teratoma: from spontaneous tumors to the pluripotency/malignancy assay (English)

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5 September 2017

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Floriana Bulic-Jakus

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5 September 2017

Ana Katusic Bojanac

2

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5 September 2017

Gordana Juric-Lekic

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5 September 2017

Maja Vlahovic

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5 September 2017

Nino Sincic

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5 September 2017

publication date

23 December 2015

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Wiley interdisciplinary reviews. Developmental biology

5 September 2017

published in

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5 September 2017

volume

5

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5 September 2017

issue

2

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5 September 2017

page(s)

186-209

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Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

5 September 2017

cites work

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Spontaneous Testicular Teratomas in an Inbred Strain of Mice

21 January 2018

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Ovarian neoplasms in F344 rats and B6C3F1 mice

21 January 2018

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The development of teratomas from parthenogenetically activated ovarian mouse eggs

21 January 2018

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The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours

21 January 2018

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Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice

21 January 2018

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Lessons from human teratomas to guide development of safe stem cell therapies.

21 January 2018

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Prenatal assessment and management of sacrococcygeal teratoma

21 January 2018

1 reference

Teratomas in infancy and childhood. A 54-year experience at the Children's Hospital Medical Center

21 January 2018

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Retroperitoneal teratoma with somatic malignant transformation: a papillary renal cell carcinoma in a testicular germ cell tumour metastasis following platinum-based chemotherapy

21 January 2018

1 reference

Biology of childhood germ cell tumours, focussing on the significance of microRNAs

21 January 2018

1 reference

Characterization of a human ovarian teratocarcinoma-derived cell line

21 January 2018

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Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

21 January 2018

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Human stem cell therapy in ischaemic stroke: a review

21 January 2018

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5-azacytidine enhances proliferation in transplanted rat fetal epiglottis

21 January 2018

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Epiblast-derived stem cells in embryonic and adult tissues.

21 January 2018

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An in vivo model of human small intestine using pluripotent stem cells

21 January 2018

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Chemically defined protein-free in vitro culture of mammalian embryo does not restrict its developmental potential for differentiation of skin appendages.

21 January 2018

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The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos

21 January 2018

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Development of teratomas from the ectoderm of mouse egg cylinders

21 January 2018

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Angiogenesis and vascular network of teratocarcinoma from embryonic stem cell transplant into seminiferous tubules.

21 January 2018

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Extrauterine growth of mouse egg-cylinders results in malignant teratoma.

21 January 2018

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Embryo-derived teratocarcinomas elicit splenomegaly in syngeneic host.

21 January 2018

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Development of Teratocarcinomas and Teratomas in Severely Immunodeficient NOD.Cg-Prkdc(scid) Il2rg(tm1Wjl)/Szj (NSG) Mice

21 January 2018

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Teratocarcinomas rarely develop from embryos transplanted into athymic mice

21 January 2018

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DNA methylation and cancer: ghosts and angels above the genes

21 January 2018

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Cancer epigenomics: beyond genomics

21 January 2018

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The effect of cells transferred into the mouse blastocyst on subsequent development

21 January 2018

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Successive generations of mice produced from an established culture line of euploid teratocarcinoma cells

21 January 2018

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Consensus guidance for banking and supply of human embryonic stem cell lines for research purposes

21 January 2018

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From naïve pluripotency to chimeras: a new ethical challenge?

21 January 2018

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Derivation of novel human ground state naive pluripotent stem cells

21 January 2018

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Systematic identification of culture conditions for induction and maintenance of naive human pluripotency

21 January 2018

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Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells

21 January 2018

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Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine

21 January 2018

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The tumorigenicity of human embryonic and induced pluripotent stem cells

21 January 2018

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Reconsidering pluripotency tests: do we still need teratoma assays?

21 January 2018

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The teratoma assay: an in vivo assessment of pluripotency

21 January 2018

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Induction of pluripotency by defined factors

21 January 2018

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Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

21 January 2018

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Immunosurgery of mouse blastocyst

21 January 2018

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Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

21 January 2018

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The ability of EK cells to form chimeras after selection of clones in G418 and some observations on the integration of retroviral vector proviral DNA into EK cells.

21 January 2018

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

21 January 2018

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Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

21 January 2018

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Gene targeting in the rat: advances and opportunities

21 January 2018

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A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo.

21 January 2018

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Mapping the route from naive pluripotency to lineage specification.

21 January 2018

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Naive pluripotency is associated with global DNA hypomethylation

21 January 2018

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FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency

21 January 2018

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The ground state of embryonic stem cell self-renewal

21 January 2018

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Capture of authentic embryonic stem cells from rat blastocysts

21 January 2018

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Production of p53 gene knockout rats by homologous recombination in embryonic stem cells

21 January 2018

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Regulatory principles of pluripotency: from the ground state up.

21 January 2018

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Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells

21 January 2018

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Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice

21 January 2018

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How to make a primordial germ cell

21 January 2018

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Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.

21 January 2018

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Androgenetic haploid embryonic stem cells produce live transgenic mice.

21 January 2018

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Genetic modification and screening in rat using haploid embryonic stem cells

21 January 2018

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Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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Generation of germline-competent induced pluripotent stem cells

21 January 2018

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Direct reprogramming of rat neural precursor cells and fibroblasts into pluripotent stem cells

21 January 2018

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Generation of rat induced pluripotent stem cells using a plasmid vector and possible application of a keratan sulfate glycan recognizing antibody in discriminating teratoma formation phenotypes.

21 January 2018

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Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells

21 January 2018

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Genome-wide functional analysis reveals factors needed at the transition steps of induced reprogramming.

21 January 2018

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Deterministic direct reprogramming of somatic cells to pluripotency

21 January 2018

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Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells

21 January 2018

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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

21 January 2018

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Reprogramming in vivo produces teratomas and iPS cells with totipotency features.

21 January 2018

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An operational definition of epigenetics

21 January 2018

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Syncytiotrophoblastic giant cells in teratocarcinoma-like tumors derived from Parp-disrupted mouse embryonic stem cells.

21 January 2018

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PARP-1 activation in the ERK signaling pathway

21 January 2018

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Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast.

21 January 2018

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Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

21 January 2018

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Generation of pluripotent stem cells via protein transduction

21 January 2018

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Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

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Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds

21 January 2018

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Divergent reprogramming routes lead to alternative stem-cell states

21 January 2018

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Embryonic stem cell lines derived from human blastocysts

21 January 2018

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Derivation of pluripotent stem cells from cultured human primordial germ cells

21 January 2018

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Human embryonic stem cell lines derived from single blastomeres

21 January 2018

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A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes

21 January 2018

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Human embryonic stem cells derived by somatic cell nuclear transfer.

21 January 2018

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Human somatic cell nuclear transfer using adult cells.

21 January 2018

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Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells

21 January 2018

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Towards germline gene therapy of inherited mitochondrial diseases

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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New lessons learned from disease modeling with induced pluripotent stem cells

21 January 2018

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Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.

21 January 2018

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Reprogramming of cell fate: epigenetic memory and the erasure of memories past

21 January 2018

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Kinome-wide functional analysis highlights the role of cytoskeletal remodeling in somatic cell reprogramming.

21 January 2018

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Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

21 January 2018

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Abnormalities in human pluripotent cells due to reprogramming mechanisms

21 January 2018

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Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells

21 January 2018

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BCL-XL mediates the strong selective advantage of a 20q11.21 amplification commonly found in human embryonic stem cell cultures.

21 January 2018

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The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response

21 January 2018

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Human embryonic stem cells are prone to generate primitive, undifferentiated tumors in engrafted human fetal tissues in severe combined immunodeficient mice

21 January 2018

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Immunogenicity of induced pluripotent stem cells

21 January 2018

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Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells

21 January 2018

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Disparate hypervariable region-1 of mitochondrial DNA did not induce skin allograft rejection in cloned porcine models

21 January 2018

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Acute rejection after swine leukocyte antigen-matched kidney allo-transplantation in cloned miniature pigs with different mitochondrial DNA-encoded minor histocompatibility antigen.

21 January 2018

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Reduced immunogenicity of induced pluripotent stem cells derived from Sertoli cells

21 January 2018

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The immunogenicity of cells derived from induced pluripotent stem cells

21 January 2018

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Induction of macrophage-like immunosuppressive cells from mouse ES cells that contribute to prolong allogeneic graft survival

21 January 2018

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Improved safety of hematopoietic transplantation with monkey embryonic stem cells in the allogeneic setting.

21 January 2018

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Concise review: The evolution of human pluripotent stem cell culture: from feeder cells to synthetic coatings

21 January 2018

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A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs

21 January 2018

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Aneuploidy in pluripotent stem cells and implications for cancerous transformation

21 January 2018

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Teratoma formation by human embryonic stem cells is site dependent and enhanced by the presence of Matrigel.

21 January 2018

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Matrigel: a complex protein mixture required for optimal growth of cell culture.

21 January 2018

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Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies.

21 January 2018

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Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny

21 January 2018

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In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium

21 January 2018

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Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection

21 January 2018

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Genetic and epigenetic variations in iPSCs: potential causes and implications for application

21 January 2018

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Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration

21 January 2018

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Embryonic stem cell trials for macular degeneration: a preliminary report

21 January 2018

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Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies

21 January 2018

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Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patients

21 January 2018

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Inhibition of pluripotent stem cell-derived teratoma formation by small molecules

21 January 2018

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CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation

21 January 2018

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Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinson's disease

21 January 2018

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Identification of aneuploidy-selective antiproliferation compounds

21 January 2018

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Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein

21 January 2018

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Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation

21 January 2018

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Inducible apoptosis as a safety switch for adoptive cell therapy

21 January 2018

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Development of an inducible caspase-9 safety switch for pluripotent stem cell-based therapies

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WDEV.219

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5 September 2017

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