Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays (Q38688677)

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English	Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays	scientific article

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9 March 2020

Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays (English)

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9 March 2020

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9 March 2020

Alejandro Giorgetti

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Mirko Busato

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Francesca Gasparini

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Erica Diani

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Maria Grazia Romanelli

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Scientific Reports

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Lipid metabolism in patients infected with Nef-deficient HIV-1 strain

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6 September 2017

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6 September 2017

HLA-C and HIV-1: friends or foes?

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6 September 2017

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6 September 2017

Lipids and membrane microdomains in HIV-1 replication

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6 September 2017

HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells

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6 September 2017

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6 September 2017

The assessment of methods for protein structure prediction.

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6 September 2017

HADDOCK versus HADDOCK: new features and performance of HADDOCK2.0 on the CAPRI targets

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6 September 2017

Dynamin 2 is required for the enhancement of HIV-1 infectivity by Nef.

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6 September 2017

Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor.

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6 September 2017

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6 September 2017

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6 September 2017

HADDOCK: a protein-protein docking approach based on biochemical or biophysical information

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6 September 2017

Characterization of an acyl-coA thioesterase that functions as a major regulator of peroxisomal lipid metabolism

1 reference

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6 September 2017

Protein structure prediction and structural genomics

1 reference

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6 September 2017

Electrostatics of nanosystems: application to microtubules and the ribosome

1 reference

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6 September 2017

Crystal structure of the Escherichia coli thioesterase II, a homolog of the human Nef binding enzyme

1 reference

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6 September 2017

The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation

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6 September 2017

Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions

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6 September 2017

Cytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes

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6 September 2017

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

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6 September 2017

The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

1 reference

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6 September 2017

Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

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6 September 2017

Identification of peroxisomal acyl-CoA thioesterases in yeast and humans

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6 September 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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6 September 2017

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4772117

6 September 2017

A novel acyl-CoA thioesterase enhances its enzymatic activity by direct binding with HIV Nef

1 reference

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6 September 2017

Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation

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6 September 2017

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

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6 September 2017

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

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6 September 2017

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

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6 September 2017

Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

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6 September 2017

Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.

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6 September 2017

The palmitoylated cysteine of the cytoplasmic tail of alpha 2A-adrenergic receptors confers subtype-specific agonist-promoted downregulation

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6 September 2017

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6 September 2017

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

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6 September 2017

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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6 September 2017

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6 September 2017

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

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6 September 2017

Antiviral activity of the proteasome on incoming human immunodeficiency virus type 1.

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14 September 2017

Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor

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14 September 2017

AP-2 Is the Crucial Clathrin Adaptor Protein for CD4 Downmodulation by HIV-1 Nef in Infected Primary CD4+ T Cells

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25 September 2017

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

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25 September 2017

Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

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25 September 2017

Inhibition of the receptor-mediated endocytosis of diferric transferrin is associated with the covalent modification of the transferrin receptor with palmitic acid.

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25 September 2017

The low affinity neurotrophin receptor, p75LNTR, is palmitoylated by thioester formation through cysteine 279.

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25 September 2017

HTLV-1 Tax protein recruitment into IKKε and TBK1 kinase complexes enhances IFN-I expression.

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23 June 2018

Conservation of cytotoxic T lymphocyte (CTL) epitopes as a host strategy to constrain parasite adaptation: evidence from the nef gene of human immunodeficiency virus 1 (HIV-1).

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23 June 2018

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1 reference

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23 June 2018

Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase

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31 August 2018

Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein

1 reference

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31 August 2018

Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.

1 reference

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31 August 2018

Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein

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31 August 2018

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

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31 August 2018

Oligomerization of the Nef protein from human immunodeficiency virus (HIV) type 1.

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31 August 2018

The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin.

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21 January 2018

Carboxyl-terminal consensus Ser-Lys-Leu-related tripeptide of peroxisomal proteins functions in vitro as a minimal peroxisome-targeting signal

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https://pubmed.ncbi.nlm.nih.gov/26927806

12 December 2020

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