Targeting local vascular and systemic consequences of inflammation on vascular and cardiac valve calcification (Q38703771)

5 September 2017

Targeting local vascular and systemic consequences of inflammation on vascular and cardiac valve calcification (English)

1 reference

5 September 2017

Ana B Sanz

4

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Alberto Ortiz

object named as

Alberto Ortiz

5

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author name string

Lucie Hénaut

1

1 reference

5 September 2017

Maria Dolores Sanchez-Nino

2

1 reference

5 September 2017

Gonzalo Aldamiz-Echevarría Castillo

3

1 reference

5 September 2017

language of work or name

English

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publication date

7 September 2015

1 reference

Expert Opinion on Therapeutic Targets

5 September 2017

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5 September 2017

20

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5 September 2017

1

1 reference

5 September 2017

89-105

1 reference

Vascular calcifications as a marker of increased cardiovascular risk: a meta-analysis

5 September 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Peripheral vascular calcification in long-haemodialysis patients: associated factors and survival consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Basic calcium phosphate crystals induce monocyte/macrophage IL-1β secretion through the NLRP3 inflammasome in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Prevalence of CKD and comorbid illness in elderly patients in the United States: results from the Kidney Early Evaluation Program (KEEP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Large artery calcification on dialysis patients is located in the intima and related to atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Arterial calcification in chronic kidney disease: key roles for calcium and phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Monocyte/macrophage regulation of vascular calcification in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Induction of bone-type alkaline phosphatase in human vascular smooth muscle cells: roles of tumor necrosis factor-alpha and oncostatin M derived from macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

PERK-eIF2α-ATF4-CHOP signaling contributes to TNFα-induced vascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/- mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Tumor necrosis factor-alpha increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Adiponectin antagonizes stimulatory effect of tumor necrosis factor-alpha on vascular smooth muscle cell calcification: regulation of growth arrest-specific gene 6-mediated survival pathway by adenosine 5'-monophosphate-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

TNFR1-activated reactive oxidative species signals up-regulate osteogenic Msx2 programs in aortic myofibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Cell-specific effects of TNF-α and IL-1β on alkaline phosphatase: implication for syndesmophyte formation and vascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Association between plasma LDL particle size, valvular accumulation of oxidized LDL, and inflammation in patients with aortic stenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Klotho deficiency causes vascular calcification in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Bone marrow- or vessel wall-derived osteoprotegerin is sufficient to reduce atherosclerotic lesion size and vascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Enhanced mineralization potential of vascular cells from SM22α-Rankl (tg) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Increased calcification in osteoprotegerin-deficient smooth muscle cells: Dependence on receptor activator of NF-κB ligand and interleukin 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Osteoprotegerin and kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Osteoprotegerin inhibits aortic valve calcification and preserves valve function in hypercholesterolemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kappaB and induction of insulin-like growth factor-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 phosphorylation-, and NFkappaB-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Differential expression of TRAIL and its receptors relative to calcification in AAA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Aortic valvular interstitial cells apoptosis and calcification are mediated by TNF-related apoptosis-inducing ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

The involvement of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

TRAIL-deficiency accelerates vascular calcification in atherosclerosis via modulation of RANKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Nalp3 inflammasome is activated and required for vascular smooth muscle cell calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Interleukin-1 beta promotes matrix metalloproteinase expression and cell proliferation in calcific aortic valve stenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Biomarkers associated with vascular and valvular calcification in chronic hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Oncostatin M is expressed in atherosclerotic lesions: a role for Oncostatin M in the pathogenesis of atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

CTRP family: linking immunity to metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Effects of the new adiponectin paralogous protein CTRP-3 and of LPS on cytokine release from monocytes of patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Viral and bacterial patterns induce TLR-mediated sustained inflammation and calcification in aortic valve interstitial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Liver x receptor agonists inhibit cytokine-induced osteopontin expression in macrophages through interference with activator protein-1 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Angiotensin II-induced osteopontin expression in vascular smooth muscle cells involves Gq/11, Ras, ERK, Src and Ets-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Osteopontin-hydroxyapatite interactions in vitro: inhibition of hydroxyapatite formation and growth in a gelatin-gel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Vascular calcification and aortic fibrosis: a bifunctional role for osteopontin in diabetic arteriosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

HMGB1 and RAGE in inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

RANKL-OPG and RAGE modulation in vascular calcification and diabetes: novel targets for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Advanced glycation of beta 2-microglobulin in the pathogenesis of bone lesions in dialysis-associated amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

RAGE: therapeutic target and biomarker of the inflammatory response--the evidence mounts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

High mobility group box 1 (HMGB1) mediates high-glucose-induced calcification in vascular smooth muscle cells of saphenous veins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Circulating levels of soluble receptor for advanced glycation end product are inversely associated with vascular calcification in patients on haemodialysis independent of S100A12 (EN-RAGE) levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Fetuin-A-containing calciprotein particles reduce mineral stress in the macrophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Inflamm-aging. An evolutionary perspective on immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Proinflammation: the key to arterial aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Calpain-1 regulation of matrix metalloproteinase 2 activity in vascular smooth muscle cells facilitates age-associated aortic wall calcification and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Klotho suppresses RIG-I-mediated senescence-associated inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Endothelial microparticles mediate inflammation-induced vascular calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Aerobic exercise reverses arterial inflammation with aging in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Regulation of oxidative stress by the anti-aging hormone klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Fibroblast growth factor 23 accelerates phosphate-induced vascular calcification in the absence of Klotho deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Paricalcitol effects on activities and metabolism of platelet activating factor and on inflammatory cytokines in hemodialysis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Cholecalciferol supplementation alters calcitriol-responsive monocyte proteins and decreases inflammatory cytokines in ESRD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

RANKL inhibition with denosumab does not influence 3-year progression of aortic calcification or incidence of adverse cardiovascular events in postmenopausal women with osteoporosis and high cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Estrogen therapy and coronary-artery calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Estrogen inhibits vascular calcification via vascular RANKL system: common mechanism of osteoporosis and vascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Phosphate: a stealthier killer than previously thought?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

Effects of phosphate binders in moderate CKD

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2015.1081685

10.1517/14728222.2015.1081685

21 January 2018

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DOI

1 reference

5 September 2017

1 reference