A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells (Q38704022)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells (English)

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

transmembrane protein

0 references

author name string

Megan M Varnum

1

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Kevin A Clayton

2

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Asuka Yoshii-Kitahara

3

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Grant Yonemoto

4

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Lacin Koro

5

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Seiko Ikezu

6

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Tsuneya Ikezu

7

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

language of work or name

0 references

publication date

10 May 2017

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Journal of Biological Chemistry

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

292

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

25

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

10651-10663

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Heterozygous TREM2 mutations in frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Essential role of MFG-E8 for phagocytic properties of microglial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2 Variants in Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Application of a split luciferase complementation assay for the detection of viral protein-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Mechanisms of function of tapasin, a critical major histocompatibility complex class I assembly factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

MFG-E8 regulates microglial phagocytosis of apoptotic neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

The TREM receptor family and signal integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Nasu-Hakola disease (polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy--PLOSL): a dementia associated with bone cystic lesions. From clinical to genetic and molecular aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Role of the cytoskeleton during leukocyte responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

TREMs in the immune system and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Monitoring Protein−Protein Interactions Using Split Synthetic Renilla Luciferase Protein-Fragment-Assisted Complementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Heterogeneity of presenile dementia with bone cysts (Nasu-Hakola disease): three genetic forms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Identification of a factor that links apoptotic cells to phagocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Purification and properties of Renilla reniformis luciferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

30 June 2018

Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

31 August 2018

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

31 August 2018

Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

31 August 2018

Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

31 August 2018

Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5481570

31 August 2018

Cutting Edge: TREM-2 Attenuates Macrophage Activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.759159

21 January 2018

Pustular psoriasis (Zumbusch) treated with 8-methoxypsoralen phototherapy (author's transl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/28490631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Split luciferase complementation assay to study protein-protein interactions in Arabidopsis protoplasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/28490631

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M116.759159

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

1 reference

Europe PubMed Central

26 June 2018

http://europepmc.org/abstract/PMC/5481570

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38704022&oldid=1778869644"