Effects of Histone Deacetylase Inhibitor (Valproic Acid) on the Expression of Hypoxia-inducible Factor-1 Alpha in Human Retinal Müller Cells (Q38714570)

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scientific article published on 2 February 2017

Language	Label	Description	Also known as
English	Effects of Histone Deacetylase Inhibitor (Valproic Acid) on the Expression of Hypoxia-inducible Factor-1 Alpha in Human Retinal Müller Cells	scientific article published on 2 February 2017

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

Effects of Histone Deacetylase Inhibitor (Valproic Acid) on the Expression of Hypoxia-inducible Factor-1 Alpha in Human Retinal Müller Cells (English)

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

author name string

Young Jun Kim

1

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

Sang Jun Park

2

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Europe PubMed Central

PMC publication ID

5 September 2017

Na Rae Kim

3

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Europe PubMed Central

PMC publication ID

5 September 2017

Hee Seung Chin

4

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

publication date

2 February 2017

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Europe PubMed Central

PMC publication ID

5 September 2017

Korean Journal of Ophthalmology

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Europe PubMed Central

PMC publication ID

5 September 2017

31

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Europe PubMed Central

PMC publication ID

5 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

80-85

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

copyright license

Creative Commons Attribution-NonCommercial 3.0 Unported

1 January 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Valproic acid inhibits tumor angiogenesis in mice transplanted with Kasumi‑1 leukemia cells

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6 September 2017

Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation

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6 September 2017

HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia

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6 September 2017

Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage

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6 September 2017

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

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6 September 2017

Targeting the hypoxia-inducible factor (HIF) pathway in cancer.

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HIF-1: a key mediator in hypoxia.

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Hypoxia: a key regulator of angiogenesis in cancer

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Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha

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Clinical development of histone deacetylase inhibitors as anticancer agents

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Exploiting tumour hypoxia in cancer treatment

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Hypoxia inducible factor-1alpha as a cancer drug target

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Hypoxia inducible factor as a cancer drug target

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Important Causes of Visual Impairment in the World Today

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6 September 2017

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

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6 September 2017

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

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Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

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6 September 2017

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

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Histone deacetylase inhibitors as new cancer drugs

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6 September 2017

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

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Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy

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Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

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Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

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Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha

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Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia

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Valproic acid regulates antioxidant enzymes and prevents ischemia/reperfusion injury in the rat retina.

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Müller cell-derived VEGF is a significant contributor to retinal neovascularization

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Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells.

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1 reference

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31 August 2018

Is HIF-1 alpha a valid therapeutic target?

1 reference

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31 August 2018

Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1alpha activity

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Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis

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31 August 2018

Hypoxic regulation of vascular endothelial growth factor in retinal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28243027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of valproic acid on proliferation, apoptosis, angiogenesis and metastasis of ovarian cancer in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/28243027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of vascular endothelial growth factor and astrocyte degeneration in the genesis of retinopathy of prematurity

1 reference

https://pubmed.ncbi.nlm.nih.gov/28243027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischaemia-induced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Müller cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28243027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-Inducible Factor-1 (HIF-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/28243027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3341/KJO.2017.31.1.80

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 September 2017

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