Pathological role of large intestinal IL-12p40 for the induction of Th2-type allergic diarrhea (Q38730445)

5 September 2017

Pathological role of large intestinal IL-12p40 for the induction of Th2-type allergic diarrhea (English)

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5 September 2017

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Ayako Hino

1

1 reference

5 September 2017

Mi-Na Kweon

2

1 reference

5 September 2017

Kohtaro Fujihashi

3

1 reference

5 September 2017

Jerry R McGhee

4

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5 September 2017

Hiroshi Kiyono

5

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5 September 2017

language of work or name

English

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publication date

1 April 2004

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The American Journal of Pathology

5 September 2017

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5 September 2017

164

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5 September 2017

4

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5 September 2017

1327-1335

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Chronic helminth infection induces alternatively activated macrophages expressing high levels of CCR5 with low interleukin-12 production and Th2-biasing ability.

5 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Shear-dependent eosinophil transmigration on interleukin 4-stimulated endothelial cells: a role for endothelium-associated eotaxin-3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

IL-12 and Th1 immune responses in human Peyer's patches

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Interleukin 12 p40 production by barrier epithelial cells during airway inflammation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Double immunolabeling of neuropeptides in the human hypothalamus as analyzed by confocal laser scanning fluorescence microscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Autocrine IL-15 mediates intestinal epithelial cell death via the activation of neighboring intraepithelial NK cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Systemically derived large intestinal CD4(+) Th2 cells play a central role in STAT6-mediated allergic diarrhea

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Molecular cloning and characterization of murine IL-12 genes.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Reduced T helper 1 responses in IL-12 p40 transgenic mice.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

In vivo production and function of IL-12 p40 homodimers.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

The inverse association between tuberculin responses and atopic disorder.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Suppression of IL-12 production by soluble CD40 ligand: evidence for involvement of the p44/42 mitogen-activated protein kinase pathway

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Contrasting roles of IL-12p40 and IL-12p35 in the development of hapten-induced colitis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Dynamics of antigen-specific helper T cells at the initiation of airway eosinophilic inflammation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1615363

A pathological function for eotaxin and eosinophils in eosinophilic gastrointestinal inflammation

31 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

Negative feedback mechanism suppresses interleukin-12 production by antigen-presenting cells interacting with T helper 2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

INTERFERON γ PRIMING IS NOT CRITICAL FOR IL-12 PRODUCTION OF MURINE SPLEEN CELLS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

Immune monitoring in whole blood using real-time PCR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

The antigen dose determines T helper subset development by regulation of CD40 ligand

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

IL-12-dependent vascular cell adhesion molecule-1 expression contributes to airway eosinophilic inflammation in a mouse model of asthma-like reaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

CD40 and epithelial cells: across the great divide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963219-1

Peyer's patch eosinophils: identification, characterization, and regulation by mucosal allergen exposure, interleukin-5, and eotaxin

7 January 2021

1 reference

12 December 2020

Differential effects of IL-12 receptor blockade with IL-12 p40 homodimer on the induction of CD4+ and CD8+ IFN-gamma-producing cells

1 reference

12 December 2020

CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions

1 reference

12 December 2020

Lack of orally induced systemic unresponsiveness in IFN-gamma knockout mice

1 reference

12 December 2020

10.1016/S0002-9440(10)63219-1

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DOI

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5 September 2017

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5 September 2017

1 reference