Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism (Q38743892)

5 July 2018

title

Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism (English)

1 reference

5 July 2018

author

Yi Yang

17

1 reference

5 July 2018

Joseph Loscalzo

16

object named as

Joseph Loscalzo

1 reference

5 July 2018

Rongkun Tao

1

1 reference

5 July 2018

Yuzheng Zhao

2

1 reference

5 July 2018

Huanyu Chu

3

1 reference

5 July 2018

Aoxue Wang

4

1 reference

5 July 2018

Jiahuan Zhu

5

1 reference

5 July 2018

Xianjun Chen

6

1 reference

5 July 2018

Yejun Zou

7

1 reference

5 July 2018

Mei Shi

8

1 reference

5 July 2018

Renmei Liu

9

1 reference

5 July 2018

Ni Su

10

1 reference

5 July 2018

Jiulin Du

11

1 reference

5 July 2018

Hai-Meng Zhou

12

1 reference

5 July 2018

Linyong Zhu

13

1 reference

5 July 2018

Xuhong Qian

14

1 reference

5 July 2018

Haiyan Liu

15

1 reference

5 July 2018

publication date

5 June 2017

1 reference

5 July 2018

published in

Nature Methods

1 reference

5 July 2018

volume

14

1 reference

5 July 2018

issue

7

1 reference

5 July 2018

page(s)

720-728

1 reference

5 July 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5555402/fullTextXML

inferred from PubMed Central ID database lookup

cites work

In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD(+)/NADH redox state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Real-time and high-throughput analysis of mitochondrial metabolic states in living cells using genetically encoded NAD+/NADH sensors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

G6PD protects from oxidative damage and improves healthspan in mice.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

The Emerging Hallmarks of Cancer Metabolism

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Separating NADH and NADPH fluorescence in live cells and tissues using FLIM

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

AMPK at the nexus of energetics and aging.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Modulation of oxidative stress as an anticancer strategy

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Genetically encoded fluorescent indicator for imaging NAD(+)/NADH ratio changes in different cellular compartments

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Identification and characterization of a human mitochondrial NAD kinase

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

How cancer metabolism is tuned for proliferation and vulnerable to disruption

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Genetically encoded fluorescent sensors for intracellular NADH detection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

An expanded palette of genetically encoded Ca²⁺ indicators

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

A fluorescent reporter of AMPK activity and cellular energy stress

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

GLUT1 and GLUT9 as major contributors to glucose influx in HepG2 cells identified by a high sensitivity intramolecular FRET glucose sensor

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

NAD kinase levels control the NADPH concentration in human cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Blocking NO synthesis: how, where and why?

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Circularly permuted green fluorescent proteins engineered to sense Ca2+.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Importance of glucose-6-phosphate dehydrogenase activity for cell growth

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Differences in nitric oxide synthase activity in a macrophage-like cell line, RAW264.7 cells, treated with lipopolysaccharide (LPS) in the presence or absence of interferon-gamma (IFN-gamma): possible heterogeneity of iNOS activity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

The redox state of free nicotinamide-adenine dinucleotide phosphate in the cytoplasm of rat liver

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Biosensor reveals multiple sources for mitochondrial NAD⁺.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(+).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Method for accurate determination of dissociation constants of optical ratiometric systems: chemical probes, genetically encoded sensors, and interacting molecules.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

AMPK is a direct adenylate charge-regulated protein kinase.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

A genetically encoded fluorescent reporter of ATP:ADP ratio

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Comparison of protein active site structures for functional annotation of proteins and drug design

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5555402

Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.4306

7 January 2021

inferred from DOI database lookup

Repression of the E coli recA gene requires at least two LexA protein monomers

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.4306

7 January 2021

inferred from DOI database lookup

Single extraction method for the spectrophotometric quantification of oxidized and reduced pyridine nucleotides in erythrocytes

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.4306

7 January 2021

inferred from DOI database lookup

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28581494

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NMETH.4306

1 reference

5 July 2018

Dimensions Publication ID

0 references

1 reference

5 July 2018

PubMed publication ID

28581494

1 reference

5 July 2018